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The map label for this gene is radA [H]

Identifier: 197105004

GI number: 197105004

Start: 1741595

End: 1742962

Strand: Reverse

Name: radA [H]

Synonym: PHZ_c1541

Alternate gene names: 197105004

Gene position: 1742962-1741595 (Counterclockwise)

Preceding gene: 197105006

Following gene: 197105003

Centisome position: 43.61

GC content: 73.68

Gene sequence:

>1368_bases
GTGGCCCGCGACGGCGCCGTCTATGCCTGCCAGTCCTGCGGCGCCGTGCAGACCCGCTGGTCCGGGCAGTGTCCCGCCTG
CGGGGCCTGGAACTCGCTGGTCGAGGAGCTGACCAGCCGCCCGCCGGGCGCCCTGAAGCCGTCCAAGGCGACCCGCGCCC
GGGGCCTGGCCTTCCAGGGCCTGGAGGACGCCACCCCTGCCCCTCCGCGCATCGCCACGGGCGTGGAGGAGTTCGACCGC
GTGTGCGGCGGCGGGGTCGTGCCGGGCTCGGCCATCCTGCTGGGCGGCGATCCCGGCGTGGGCAAGTCCACGCTCCTGCT
GCAGGTGGCCGCCAGCGCCGCCCGCCGGGGCGCCCGCTGCGCCTACATCTCTGGCGAAGAGGCCGTGGAGCAGGTTCGCG
GCCGTGCCCAGCGCATGGGCCTGGCCGACGCGCCGGTGAAGCTCGCCGCCGAGACCAGCCTGCGGGCCATCACCGACGGG
CTGAAGGCCGAGGACTTCGACCTGGTGGTGATCGATTCCATCCAGACCCTGTGGAGCGACGCCCACGAGGCAGGGCCGGG
CTCCGTCACCCAGGTGCGCGCCGCCGCAGGCGAGCTGGTGCGTCTGGCGAAGAAGCGGGGGCTGGCGGTGATCCTCGTCG
GCCACGTGACCAAGGAAGGCACGATCGCCGGTCCCCGGGTCGTGGAGCACATGGTGGACGCCGTCTTCGCCTTCGAGGGC
GAGCGCGGCTATCCCTTCCGCATCCTGCGCGGCGCCAAGAACCGCTTCGGCGCCACCGACGAGATCGGCGTGTTCGAGAT
GAACGACGCGGGCCTCTCCGAGGTGAAGAACCCCTCGGCGCTGTTCCTCAACACCTCGGGCGAGCGGGCGGCCGGCGCGG
CGGTGTTCGCGGGCATCGAGGGCTCGCGCCCCGTCCTGGTGGAGATCCAGGCGCTCGTCGCCCCCTCGGCCTACGGCACG
CCCCGAAGGGCGGTGGTCGGCTGGGATTCCGGGCGGCTGGCGATGGTGCTGGCGGTCCTGGAGGCCCGGTGCGGCCTTGG
TTTCGGGGACCGGGACGTCTATCTGAACGTGGCGGGGGGCCTTCGGATCACCGAGCCCGCCGCAGACCTCGCCGCCGCCG
CGGCGCTCGCCTCTTCCGCCTTCGACCAGGCCCTGCCGCAGGACTGCGTGGTCTTCGGCGAGATCAGCCTGTCGGGCGAG
GTGCGCTCGGTCAGCCGGATGGACGCCCGCCTGAAGGAGGCCGCAAAGCTCGGCTTCCGTCGCGGGCTCGGTCCCGCCGA
CGTCGAAGCCGCGGGCGGCATGACATTCACCGGGGTGAGCCGCCTCGCGGACGCCGTTCGCCGGATCGGCGACGGCGCAT
GGGACTAG

Upstream 100 bases:

>100_bases
CGAACAGCTCCCGGCATCTGACTAGCACGCGCCGCGTGGCCGCACAGACCCCGGCGCTGCGGTCGGCTAGACTTGGGATC
CCTCGAATCAGGAGCATCCC

Downstream 100 bases:

>100_bases
GAATGACGCAGTTCGATTTCATCGTCCTGGCGCTGCTGCTGATTTCGGCGGCGGTCGGCTTCGCCAGGGGCGCGGTGCGC
GAGATCGCGGCCCTCGTGGC

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MARDGAVYACQSCGAVQTRWSGQCPACGAWNSLVEELTSRPPGALKPSKATRARGLAFQGLEDATPAPPRIATGVEEFDR
VCGGGVVPGSAILLGGDPGVGKSTLLLQVAASAARRGARCAYISGEEAVEQVRGRAQRMGLADAPVKLAAETSLRAITDG
LKAEDFDLVVIDSIQTLWSDAHEAGPGSVTQVRAAAGELVRLAKKRGLAVILVGHVTKEGTIAGPRVVEHMVDAVFAFEG
ERGYPFRILRGAKNRFGATDEIGVFEMNDAGLSEVKNPSALFLNTSGERAAGAAVFAGIEGSRPVLVEIQALVAPSAYGT
PRRAVVGWDSGRLAMVLAVLEARCGLGFGDRDVYLNVAGGLRITEPAADLAAAAALASSAFDQALPQDCVVFGEISLSGE
VRSVSRMDARLKEAAKLGFRRGLGPADVEAAGGMTFTGVSRLADAVRRIGDGAWD

Sequences:

>Translated_455_residues
MARDGAVYACQSCGAVQTRWSGQCPACGAWNSLVEELTSRPPGALKPSKATRARGLAFQGLEDATPAPPRIATGVEEFDR
VCGGGVVPGSAILLGGDPGVGKSTLLLQVAASAARRGARCAYISGEEAVEQVRGRAQRMGLADAPVKLAAETSLRAITDG
LKAEDFDLVVIDSIQTLWSDAHEAGPGSVTQVRAAAGELVRLAKKRGLAVILVGHVTKEGTIAGPRVVEHMVDAVFAFEG
ERGYPFRILRGAKNRFGATDEIGVFEMNDAGLSEVKNPSALFLNTSGERAAGAAVFAGIEGSRPVLVEIQALVAPSAYGT
PRRAVVGWDSGRLAMVLAVLEARCGLGFGDRDVYLNVAGGLRITEPAADLAAAAALASSAFDQALPQDCVVFGEISLSGE
VRSVSRMDARLKEAAKLGFRRGLGPADVEAAGGMTFTGVSRLADAVRRIGDGAWD
>Mature_454_residues
ARDGAVYACQSCGAVQTRWSGQCPACGAWNSLVEELTSRPPGALKPSKATRARGLAFQGLEDATPAPPRIATGVEEFDRV
CGGGVVPGSAILLGGDPGVGKSTLLLQVAASAARRGARCAYISGEEAVEQVRGRAQRMGLADAPVKLAAETSLRAITDGL
KAEDFDLVVIDSIQTLWSDAHEAGPGSVTQVRAAAGELVRLAKKRGLAVILVGHVTKEGTIAGPRVVEHMVDAVFAFEGE
RGYPFRILRGAKNRFGATDEIGVFEMNDAGLSEVKNPSALFLNTSGERAAGAAVFAGIEGSRPVLVEIQALVAPSAYGTP
RRAVVGWDSGRLAMVLAVLEARCGLGFGDRDVYLNVAGGLRITEPAADLAAAAALASSAFDQALPQDCVVFGEISLSGEV
RSVSRMDARLKEAAKLGFRRGLGPADVEAAGGMTFTGVSRLADAVRRIGDGAWD

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=452, Percent_Identity=47.1238938053097, Blast_Score=397, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 47168; Mature: 47037

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDGAVYACQSCGAVQTRWSGQCPACGAWNSLVEELTSRPPGALKPSKATRARGLAFQG
CCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCEECC
LEDATPAPPRIATGVEEFDRVCGGGVVPGSAILLGGDPGVGKSTLLLQVAASAARRGARC
CCCCCCCCCHHHHCHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEE
AYISGEEAVEQVRGRAQRMGLADAPVKLAAETSLRAITDGLKAEDFDLVVIDSIQTLWSD
EEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHH
AHEAGPGSVTQVRAAAGELVRLAKKRGLAVILVGHVTKEGTIAGPRVVEHMVDAVFAFEG
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
ERGYPFRILRGAKNRFGATDEIGVFEMNDAGLSEVKNPSALFLNTSGERAAGAAVFAGIE
CCCCCCCEEECCHHCCCCCCCCEEEEECCCCHHHCCCCCEEEEECCCCCCCCEEEEECCC
GSRPVLVEIQALVAPSAYGTPRRAVVGWDSGRLAMVLAVLEARCGLGFGDRDVYLNVAGG
CCCCEEEEEEEHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECC
LRITEPAADLAAAAALASSAFDQALPQDCVVFGEISLSGEVRSVSRMDARLKEAAKLGFR
EEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
RGLGPADVEAAGGMTFTGVSRLADAVRRIGDGAWD
HCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ARDGAVYACQSCGAVQTRWSGQCPACGAWNSLVEELTSRPPGALKPSKATRARGLAFQG
CCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCEECC
LEDATPAPPRIATGVEEFDRVCGGGVVPGSAILLGGDPGVGKSTLLLQVAASAARRGARC
CCCCCCCCCHHHHCHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEE
AYISGEEAVEQVRGRAQRMGLADAPVKLAAETSLRAITDGLKAEDFDLVVIDSIQTLWSD
EEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHH
AHEAGPGSVTQVRAAAGELVRLAKKRGLAVILVGHVTKEGTIAGPRVVEHMVDAVFAFEG
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
ERGYPFRILRGAKNRFGATDEIGVFEMNDAGLSEVKNPSALFLNTSGERAAGAAVFAGIE
CCCCCCCEEECCHHCCCCCCCCEEEEECCCCHHHCCCCCEEEEECCCCCCCCEEEEECCC
GSRPVLVEIQALVAPSAYGTPRRAVVGWDSGRLAMVLAVLEARCGLGFGDRDVYLNVAGG
CCCCEEEEEEEHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECC
LRITEPAADLAAAAALASSAFDQALPQDCVVFGEISLSGEVRSVSRMDARLKEAAKLGFR
EEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
RGLGPADVEAAGGMTFTGVSRLADAVRRIGDGAWD
HCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]