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The map label for this gene is intZ [H]

Identifier: 197104884

GI number: 197104884

Start: 1607852

End: 1609036

Strand: Direct

Name: intZ [H]

Synonym: PHZ_c1418

Alternate gene names: 197104884

Gene position: 1607852-1609036 (Clockwise)

Preceding gene: 197104883

Following gene: 197104885

Centisome position: 40.23

GC content: 62.87

Gene sequence:

>1185_bases
ATGTACGTCCACGTCACGACCTCGGGATCGATCACCTTCCGGTACGACTACCGTCTGAATGGTCGGCGCGAGACGCTGAC
GATCGGCAAATACGGGCCATCAGGTCTGTCCCTCGCCCGAGCGCGTGAGAAGTGCCTCGACGCCCGTCGAGCGGTGGCCG
AGGGGCTTTCGCCTGCTCAGGAGAAGCAACGCGAGAAGCGGCGGGTCCTGGAAGCGAAGAGCTTCGGCGAGTTCGGTGAG
CGCTGGTTCAAAGAAGCGCCCATGGCGGACAGCACGAGGGCAATGCGGCGTTCGATCTTCGAACGCGATCTGCTTCCGGC
CTTTCGCAATCGCCTCTTGTCGGAGATCACGCCGGACGACCTGCGAGCCCTTTGCGCCAAGATCAAAGGCCGTGGCGCCC
CAGCTACCGCGATCCACGTCCGAGACATCCTCAAGCAGATTTACGGCTTCGCGATTCTTCATGGCGAGAAGATCCGAAAT
CCCGCCGACGAGGTCGGGCCGGCGTCGATCGCGACCTTCGTAGCGAAGGATCGCGCCCTATCGCCAACCGAGATCCGGAT
CATGCTGAAGCAGCTCGAGCATGTGCCGACGCTGCCGACTATCCGGCTCGGTCTAAAGCTGATCCTGCTCACGATGGTCC
GGAAGAGCGAGTTGCAGGACGCTACCTGGGATGAGGTCGACTTTGAGAACGCCGTCTGGTCCATCCCCAAGGAGCGGATG
AAGCGCTCGAAGGCCCACAACGTGTACCTGTCGGAGCAATCCCTCGACATCCTGATCGCACTGAAGACGTGCGCCGGCAA
TTCGCGGTTCCTGCTGCCATCGCGCTACGACGCCGATGCACCCATGTCCCGGGCTACGTTCAACCGCATCACGACGGCTG
TTGCGGAACGCGCGAAGAAGGAGGGGCTGCCACTCGAACCCTTCACGGTTCACGACCTGCGGCGGACCGGCTCAACCTTG
CTGAACGAGCTCGGCTTCAACCGAGACTGGATCGAGAAGGCTCTGGCCCACGAGGACAGCCGCTCGTCTCGGGGCGTCTA
CAACAAGGCCGAGTACGAGCCGCAGCGGCGGCACATGCTCCAAGAATGGGCCGACATGGTCGACGCATGGGTTGATGGCC
GGAAGCGGGCCCCGACGCTCTATCCGCCCAGCATGGAGCTCGGGCCTCTCGAAGCTACTGTCTGA

Upstream 100 bases:

>100_bases
TGGGTGACGGTATTCTCTGGAGCCGCCCGTGCTTACCGACACAGCTCTCAAGAACCTCAAGCCCAGGGAGAAGGCGTACA
AGGTCGCTGACCGCGACGGG

Downstream 100 bases:

>100_bases
CAGGTCGTGCGCGGCGCTGCCGAACGTCGGGAGATGGCGACCTAGCGATCAGGGACGCGTCTGAGGCCCGACGCCGCTCA
TCGATCCACGCCTCAACCTC

Product: integrase/recombinase, phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MYVHVTTSGSITFRYDYRLNGRRETLTIGKYGPSGLSLARAREKCLDARRAVAEGLSPAQEKQREKRRVLEAKSFGEFGE
RWFKEAPMADSTRAMRRSIFERDLLPAFRNRLLSEITPDDLRALCAKIKGRGAPATAIHVRDILKQIYGFAILHGEKIRN
PADEVGPASIATFVAKDRALSPTEIRIMLKQLEHVPTLPTIRLGLKLILLTMVRKSELQDATWDEVDFENAVWSIPKERM
KRSKAHNVYLSEQSLDILIALKTCAGNSRFLLPSRYDADAPMSRATFNRITTAVAERAKKEGLPLEPFTVHDLRRTGSTL
LNELGFNRDWIEKALAHEDSRSSRGVYNKAEYEPQRRHMLQEWADMVDAWVDGRKRAPTLYPPSMELGPLEATV

Sequences:

>Translated_394_residues
MYVHVTTSGSITFRYDYRLNGRRETLTIGKYGPSGLSLARAREKCLDARRAVAEGLSPAQEKQREKRRVLEAKSFGEFGE
RWFKEAPMADSTRAMRRSIFERDLLPAFRNRLLSEITPDDLRALCAKIKGRGAPATAIHVRDILKQIYGFAILHGEKIRN
PADEVGPASIATFVAKDRALSPTEIRIMLKQLEHVPTLPTIRLGLKLILLTMVRKSELQDATWDEVDFENAVWSIPKERM
KRSKAHNVYLSEQSLDILIALKTCAGNSRFLLPSRYDADAPMSRATFNRITTAVAERAKKEGLPLEPFTVHDLRRTGSTL
LNELGFNRDWIEKALAHEDSRSSRGVYNKAEYEPQRRHMLQEWADMVDAWVDGRKRAPTLYPPSMELGPLEATV
>Mature_394_residues
MYVHVTTSGSITFRYDYRLNGRRETLTIGKYGPSGLSLARAREKCLDARRAVAEGLSPAQEKQREKRRVLEAKSFGEFGE
RWFKEAPMADSTRAMRRSIFERDLLPAFRNRLLSEITPDDLRALCAKIKGRGAPATAIHVRDILKQIYGFAILHGEKIRN
PADEVGPASIATFVAKDRALSPTEIRIMLKQLEHVPTLPTIRLGLKLILLTMVRKSELQDATWDEVDFENAVWSIPKERM
KRSKAHNVYLSEQSLDILIALKTCAGNSRFLLPSRYDADAPMSRATFNRITTAVAERAKKEGLPLEPFTVHDLRRTGSTL
LNELGFNRDWIEKALAHEDSRSSRGVYNKAEYEPQRRHMLQEWADMVDAWVDGRKRAPTLYPPSMELGPLEATV

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=378, Percent_Identity=31.4814814814815, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788974, Length=376, Percent_Identity=32.4468085106383, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1788690, Length=372, Percent_Identity=27.4193548387097, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44789; Mature: 44789

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVHVTTSGSITFRYDYRLNGRRETLTIGKYGPSGLSLARAREKCLDARRAVAEGLSPAQ
CEEEEEECCEEEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
EKQREKRRVLEAKSFGEFGERWFKEAPMADSTRAMRRSIFERDLLPAFRNRLLSEITPDD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LRALCAKIKGRGAPATAIHVRDILKQIYGFAILHGEKIRNPADEVGPASIATFVAKDRAL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHCHHHHHHHHHHCCCC
SPTEIRIMLKQLEHVPTLPTIRLGLKLILLTMVRKSELQDATWDEVDFENAVWSIPKERM
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHH
KRSKAHNVYLSEQSLDILIALKTCAGNSRFLLPSRYDADAPMSRATFNRITTAVAERAKK
HHHHHCCEEEECCCCEEEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EGLPLEPFTVHDLRRTGSTLLNELGFNRDWIEKALAHEDSRSSRGVYNKAEYEPQRRHML
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
QEWADMVDAWVDGRKRAPTLYPPSMELGPLEATV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYVHVTTSGSITFRYDYRLNGRRETLTIGKYGPSGLSLARAREKCLDARRAVAEGLSPAQ
CEEEEEECCEEEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
EKQREKRRVLEAKSFGEFGERWFKEAPMADSTRAMRRSIFERDLLPAFRNRLLSEITPDD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LRALCAKIKGRGAPATAIHVRDILKQIYGFAILHGEKIRNPADEVGPASIATFVAKDRAL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHCHHHHHHHHHHCCCC
SPTEIRIMLKQLEHVPTLPTIRLGLKLILLTMVRKSELQDATWDEVDFENAVWSIPKERM
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHH
KRSKAHNVYLSEQSLDILIALKTCAGNSRFLLPSRYDADAPMSRATFNRITTAVAERAKK
HHHHHCCEEEECCCCEEEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EGLPLEPFTVHDLRRTGSTLLNELGFNRDWIEKALAHEDSRSSRGVYNKAEYEPQRRHML
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
QEWADMVDAWVDGRKRAPTLYPPSMELGPLEATV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]