| Definition | Phenylobacterium zucineum HLK1, complete genome. |
|---|---|
| Accession | NC_011144 |
| Length | 3,996,255 |
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The map label for this gene is gno [H]
Identifier: 197104545
GI number: 197104545
Start: 1220258
End: 1221037
Strand: Direct
Name: gno [H]
Synonym: PHZ_c1079
Alternate gene names: 197104545
Gene position: 1220258-1221037 (Clockwise)
Preceding gene: 197104544
Following gene: 197104546
Centisome position: 30.54
GC content: 70.64
Gene sequence:
>780_bases ATGGCCTTCAAACCGTTCGACCTGACCGGCAAGGTCGCGCTGGTGACCGGCGGCAACGGCGGCATCGGCCTCGGCATGGC CGAGGGCCTGGCCGCGGCCGGGGCCAAGGTGGCGATCTGGGGCCAGAACCCGGAGAAGAACGCCAAGGCCGAGGCGACGC TGAAGGGCTACGGCGTCGAGGTGCTGGTCCAGAAGGTGGACGTGGCCGACGAGCAGGCGGTGGTGGCCGGCGTCGCCGAG GCGCTGAAGACGTTCGGGCGACTGGACTTCGTGGCCGCCAACGCCGGCGTCGGCGGCGGCGCGCCGTTCCACGAGATGAC CACCGAGAAGTGGCGGCGGGTCACGACGGTGAACCTGGACGCGGTGTTCTGGACCTTCCGCGAGGCGGCCAAGCACATGA TCGAACGGGCCGAGGCGGGCGACCCCGGCGGCTCGATGGTGGTGACCTCGTCCACCTCGGCGATCCACGGCGCGCCGCGC AACCAGGCCTACGCCTCGACCAAGGCCGGGGTGATCGCCATGATCCGCGGGCTGGCGGTGGAGTACGCCCGCTACGGCAT CCGGGCCAACGCCATCCTGCCGGGCTGGATCGCCACCGACATGACCGCCGGCCTGCAGGCGTGGGACACCTTCAACGAGA AGGCCATCGGCCGGGTGCCGATGCGCCGCTGGGGCGAGGGCGAGGACTTCTCGGGCATCGCGGTGTACCTGGCCTCGGAC GCCTCGAAGTTCCACACCGGCGACAGCTTCGTCATCGACGGCGGCTACACGATCTTCTGA
Upstream 100 bases:
>100_bases GGCGGGGAGGCGGCCGCGCCCGCGCCGGCGGAATAGGGCCGCCTTGACCTCCCCTACGTCGCCCGCGCAAGTGGCGGGCA AGCAAAAGGGGAGAGACGAG
Downstream 100 bases:
>100_bases GGCCGGACTCGCCCAAGGCCGCCGCGCGCCCATGCTGACCGATCCCCTCTTCTACGTCCTCGCCGTGCCGGCGGTGACGA TGATGGGGCTGGCCAAGGGC
Product: 2-deoxy-D-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MAFKPFDLTGKVALVTGGNGGIGLGMAEGLAAAGAKVAIWGQNPEKNAKAEATLKGYGVEVLVQKVDVADEQAVVAGVAE ALKTFGRLDFVAANAGVGGGAPFHEMTTEKWRRVTTVNLDAVFWTFREAAKHMIERAEAGDPGGSMVVTSSTSAIHGAPR NQAYASTKAGVIAMIRGLAVEYARYGIRANAILPGWIATDMTAGLQAWDTFNEKAIGRVPMRRWGEGEDFSGIAVYLASD ASKFHTGDSFVIDGGYTIF
Sequences:
>Translated_259_residues MAFKPFDLTGKVALVTGGNGGIGLGMAEGLAAAGAKVAIWGQNPEKNAKAEATLKGYGVEVLVQKVDVADEQAVVAGVAE ALKTFGRLDFVAANAGVGGGAPFHEMTTEKWRRVTTVNLDAVFWTFREAAKHMIERAEAGDPGGSMVVTSSTSAIHGAPR NQAYASTKAGVIAMIRGLAVEYARYGIRANAILPGWIATDMTAGLQAWDTFNEKAIGRVPMRRWGEGEDFSGIAVYLASD ASKFHTGDSFVIDGGYTIF >Mature_258_residues AFKPFDLTGKVALVTGGNGGIGLGMAEGLAAAGAKVAIWGQNPEKNAKAEATLKGYGVEVLVQKVDVADEQAVVAGVAEA LKTFGRLDFVAANAGVGGGAPFHEMTTEKWRRVTTVNLDAVFWTFREAAKHMIERAEAGDPGGSMVVTSSTSAIHGAPRN QAYASTKAGVIAMIRGLAVEYARYGIRANAILPGWIATDMTAGLQAWDTFNEKAIGRVPMRRWGEGEDFSGIAVYLASDA SKFHTGDSFVIDGGYTIF
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=31.7460317460317, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=28.8973384030418, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=30.9236947791165, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=29.5719844357977, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=30.952380952381, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI4503301, Length=259, Percent_Identity=30.8880308880309, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=30.7392996108949, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=31.6326530612245, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=27.8625954198473, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=30.8080808080808, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=30.5676855895196, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI126723191, Length=212, Percent_Identity=30.6603773584906, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=27.0588235294118, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=28.1632653061224, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=28.6407766990291, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI226371731, Length=197, Percent_Identity=29.4416243654822, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI83715985, Length=200, Percent_Identity=29.5, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=30.4597701149425, Blast_Score=70, Evalue=2e-12, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=32.8063241106719, Blast_Score=140, Evalue=1e-34, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=33.203125, Blast_Score=137, Evalue=8e-34, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=33.201581027668, Blast_Score=134, Evalue=4e-33, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=34.2412451361868, Blast_Score=127, Evalue=7e-31, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=28.9156626506024, Blast_Score=120, Evalue=7e-29, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=32.8063241106719, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=31.2, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=31.8548387096774, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=26.9076305220884, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1789057, Length=268, Percent_Identity=26.1194029850746, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=27.7566539923954, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=28, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1787526, Length=261, Percent_Identity=28.735632183908, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1787545, Length=258, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=35.6862745098039, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=31.8725099601594, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=31.7647058823529, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=29.8892988929889, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=28.0155642023346, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=29.3436293436293, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=27.3408239700375, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=28.4132841328413, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=28.8888888888889, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=27.6363636363636, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=27.0676691729323, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=26.953125, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=26.5682656826568, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=27.6119402985075, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=30.5343511450382, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=26.4705882352941, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=26.6917293233083, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=27.2058823529412, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=28.8537549407115, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI72000259, Length=274, Percent_Identity=28.4671532846715, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=24.812030075188, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=27.0676691729323, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17568967, Length=198, Percent_Identity=31.3131313131313, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=28.0769230769231, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=25.3731343283582, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=26.8382352941176, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=25.5555555555556, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193203115, Length=209, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193203117, Length=209, Percent_Identity=24.8803827751196, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=24.8175182481752, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17564282, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=23.2323232323232, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=32.1705426356589, Blast_Score=119, Evalue=4e-28, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=35.2, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=29.5275590551181, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=29.5275590551181, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.6, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=31.25, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=29.9610894941634, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=29.2, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24665243, Length=220, Percent_Identity=35.4545454545455, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI221331218, Length=220, Percent_Identity=35.4545454545455, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI24665247, Length=221, Percent_Identity=35.7466063348416, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI221331216, Length=221, Percent_Identity=35.7466063348416, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI17737361, Length=263, Percent_Identity=31.1787072243346, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24640492, Length=200, Percent_Identity=27, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI18859837, Length=216, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24581726, Length=204, Percent_Identity=25.9803921568627, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24640442, Length=200, Percent_Identity=30, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27220; Mature: 27089
Theoretical pI: Translated: 6.53; Mature: 6.53
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAFKPFDLTGKVALVTGGNGGIGLGMAEGLAAAGAKVAIWGQNPEKNAKAEATLKGYGVE CCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCE VLVQKVDVADEQAVVAGVAEALKTFGRLDFVAANAGVGGGAPFHEMTTEKWRRVTTVNLD EEEEHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHEEEEEEHH AVFWTFREAAKHMIERAEAGDPGGSMVVTSSTSAIHGAPRNQAYASTKAGVIAMIRGLAV HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH EYARYGIRANAILPGWIATDMTAGLQAWDTFNEKAIGRVPMRRWGEGEDFSGIAVYLASD HHHHHCEEECCEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEEEEEECC ASKFHTGDSFVIDGGYTIF CCCCCCCCEEEECCCEEEC >Mature Secondary Structure AFKPFDLTGKVALVTGGNGGIGLGMAEGLAAAGAKVAIWGQNPEKNAKAEATLKGYGVE CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCE VLVQKVDVADEQAVVAGVAEALKTFGRLDFVAANAGVGGGAPFHEMTTEKWRRVTTVNLD EEEEHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHEEEEEEHH AVFWTFREAAKHMIERAEAGDPGGSMVVTSSTSAIHGAPRNQAYASTKAGVIAMIRGLAV HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH EYARYGIRANAILPGWIATDMTAGLQAWDTFNEKAIGRVPMRRWGEGEDFSGIAVYLASD HHHHHCEEECCEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEEEEEECC ASKFHTGDSFVIDGGYTIF CCCCCCCCEEEECCCEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]