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The map label for this gene is purL [H]

Identifier: 197104476

GI number: 197104476

Start: 1121052

End: 1123247

Strand: Reverse

Name: purL [H]

Synonym: PHZ_c1010

Alternate gene names: 197104476

Gene position: 1123247-1121052 (Counterclockwise)

Preceding gene: 197104478

Following gene: 197104475

Centisome position: 28.11

GC content: 71.17

Gene sequence:

>2196_bases
ATGAGCGCCCAGCCCGCAAAGACCATGGCCGAGAAGGCCGCCGAGTACGGCCTGAAGCCCGAGGAATACGACCTCATCGT
CAAGCGCCTGAACCGCGAGCCCAACGACGTGGAGCTGGGCGTGTTCTCGGTGATGTGGTCCGAGCACTGCTCGTACAAGA
GCTCGCGCAAGCACCTGGTGAAGTTCCCGACCAAGGGGCCGCGCGTGATCCAGGGGCCGGGCGAGAACGCCGGGGTCATC
GACATCGGCGACGGACAAGCCTGCATCTTCAAGATGGAGAGCCACAACCACCCGTCCTACATCGAGCCCTACCAGGGCGC
GGCGACGGGCGTCGGCGGCATCATGCGCGACGTCTTCACCATGGGCGCGCGGCCGGTGGCGCTGCTGAACGCCCTGCGGT
TCGGCGATCCCGCGCATCCGAAGACGAAGCGCCTGGTCTCGGGCGTGGTCTCCGGCATCGGCGGCTACGGCAACTGCGTG
GGCGTGCCCACCGTCGCGGGCGAGACCAACTTCCACCGCGGCTACGACGGCAACATCCTGGTCAACGCCATGTGCGTGGG
CCTGGCCGACGCCGACAAGATCTTCTACTCGGCCGCCCCCGCGCCCGGCCTGCCGGTGGTCTACTTCGGCTCCAAGACCG
GCCGCGACGGCATCCACGGCGCGACCATGGCCTCGGCCGAGTTCGACGACGCCTCGGAAGAGAAGCGCCCCACCGTCCAG
GTGGGCGACCCCTTCGCCGAGAAGCTGCTGATCGAGGCCACGCTGGAGTTGATGGCCTCGGGCGCCGTGGCCGCGATCCA
GGACATGGGCGCGGCCGGCCTCACCTCCTCGTCGGTCGAGATGGCCGGCAAGGGCGGCGTCGGCATCGAGCTCGACCTCG
ACGCCGTGCCCCAGCGCGAGGAGGGCATGACCGCCTACGAGATGATGCTGTCCGAGAGCCAGGAGCGCATGCTGGCGATC
CTGAAGCCCGGCCGCGAGGCCGATGGCCACCGCATCTTCCAGAAGTGGGGCCTGGACGCCGCGGTGATCGGCAGGACCAC
CGACACCGGCCACATCGTGCTGAAGCACCAGGGCCAGGTAGTCTGCGACGTGCCGCTCGCCCCGCTGTCGGACGACGCCC
CGCTCTACGACCGCCCCTGGGTCGCCCCCGAGGCCGCGCCCCGGCTCGACCCGGCCGACGTCCCGGCCCCCGGCGACTGG
AAGGCCGCGGTGCTCAAGCTGATGAGCGCCCCCGACATGGCCTCCAAGCGCTGGATCTGGGAACAGTACGACCGCCACGT
CATGGCCGACACGCTGGAGGATTCGGCCACCGGCGCCGACGCCGGCATCGTGCGCGTCCACGGGACCCGCAAGGCGTTGG
CCGTCACCTCCGACTGCACGCCCCGCTACGTCCAGAACGACCCCTACGAGGGCGGCAAGCAGGCCGTCGCCGAGGCCTGG
CGCAACGTCACCGCCGTGGGCGCCCTGCCGATCGCCATCACCGACAACCTGAACTTCGGCAACCCCGAGCGGCCCGAGAT
CATGGGCCAGATCGTGCGCGCCATCGAAGGCATGGCCGAGGCCTGCCGCGAGCTGGACTTCCCGGTCGTGAGCGGCAACG
TCAGCCTCTACAACGAGACCAACGGCGTCGCCATTCCCCCCACCCCCACCGTGGGCGGCGTCGGCCTGATCGAGGACTAC
GCCCACCGCGCCGACTTCTCGAACCTGGCGGCCGGCGAGGCCCTGGTGCTGGTCGGCGAGACCCAGGGCGAACTCGGCGC
CTCCATGTACCTGCGCGAGATGCTGGGCCGCGAGGACGGCGCCCCGCCACCGGTGGACCTGGCCGTCGAGCGCCGCCACG
GCGCCTTCGTGCGCGAACTGATCCGCACGGACCGGGCCCGGACCGTCCACGACCTCTCCGACGGCGGCCTGATCGCCGCG
GCCGCCGAGATGGCCCTGGCCTCGAACGTCGGCGTCACTCTCACCATCGACGGCGCGCCCCACGCGGCCCTCTTCGGCGA
GGACCAGGCCCGCTACCTGATCGGGACGGCCGATCCCGAGGCGATCCTCTCGGCGGCGAAGAAGGCCGGCGTGCCGGCCG
CCGTCGTGGGTAGGGCCGGCGGCGAGGCCGTGGCGGTCGAGGGCCTCTTCACCCTGCCCCTCGCCGAGCTGCGCCAGGCC
CACGAAGGCTGGATGCCGGCCTATATGGGCGACTAG

Upstream 100 bases:

>100_bases
CGGGCGCCGGGCGGGCGCCCTCGCCCCGGACCAACCGGGCGGACCGGCCGGATGTTCCCCCCTATCGCGCTCCCGGCAGA
GTCCCGCTAGAAGGCGCCCC

Downstream 100 bases:

>100_bases
CCGCCCTCCTCCCCCATCGGGGGAGGGCGCAGCCCGACGATCGGCGCCCGGCAAAAAGGGCGCCGTCGGGTCGGGAGGGC
GGCAGCCCGACGATCGGCGC

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MSAQPAKTMAEKAAEYGLKPEEYDLIVKRLNREPNDVELGVFSVMWSEHCSYKSSRKHLVKFPTKGPRVIQGPGENAGVI
DIGDGQACIFKMESHNHPSYIEPYQGAATGVGGIMRDVFTMGARPVALLNALRFGDPAHPKTKRLVSGVVSGIGGYGNCV
GVPTVAGETNFHRGYDGNILVNAMCVGLADADKIFYSAAPAPGLPVVYFGSKTGRDGIHGATMASAEFDDASEEKRPTVQ
VGDPFAEKLLIEATLELMASGAVAAIQDMGAAGLTSSSVEMAGKGGVGIELDLDAVPQREEGMTAYEMMLSESQERMLAI
LKPGREADGHRIFQKWGLDAAVIGRTTDTGHIVLKHQGQVVCDVPLAPLSDDAPLYDRPWVAPEAAPRLDPADVPAPGDW
KAAVLKLMSAPDMASKRWIWEQYDRHVMADTLEDSATGADAGIVRVHGTRKALAVTSDCTPRYVQNDPYEGGKQAVAEAW
RNVTAVGALPIAITDNLNFGNPERPEIMGQIVRAIEGMAEACRELDFPVVSGNVSLYNETNGVAIPPTPTVGGVGLIEDY
AHRADFSNLAAGEALVLVGETQGELGASMYLREMLGREDGAPPPVDLAVERRHGAFVRELIRTDRARTVHDLSDGGLIAA
AAEMALASNVGVTLTIDGAPHAALFGEDQARYLIGTADPEAILSAAKKAGVPAAVVGRAGGEAVAVEGLFTLPLAELRQA
HEGWMPAYMGD

Sequences:

>Translated_731_residues
MSAQPAKTMAEKAAEYGLKPEEYDLIVKRLNREPNDVELGVFSVMWSEHCSYKSSRKHLVKFPTKGPRVIQGPGENAGVI
DIGDGQACIFKMESHNHPSYIEPYQGAATGVGGIMRDVFTMGARPVALLNALRFGDPAHPKTKRLVSGVVSGIGGYGNCV
GVPTVAGETNFHRGYDGNILVNAMCVGLADADKIFYSAAPAPGLPVVYFGSKTGRDGIHGATMASAEFDDASEEKRPTVQ
VGDPFAEKLLIEATLELMASGAVAAIQDMGAAGLTSSSVEMAGKGGVGIELDLDAVPQREEGMTAYEMMLSESQERMLAI
LKPGREADGHRIFQKWGLDAAVIGRTTDTGHIVLKHQGQVVCDVPLAPLSDDAPLYDRPWVAPEAAPRLDPADVPAPGDW
KAAVLKLMSAPDMASKRWIWEQYDRHVMADTLEDSATGADAGIVRVHGTRKALAVTSDCTPRYVQNDPYEGGKQAVAEAW
RNVTAVGALPIAITDNLNFGNPERPEIMGQIVRAIEGMAEACRELDFPVVSGNVSLYNETNGVAIPPTPTVGGVGLIEDY
AHRADFSNLAAGEALVLVGETQGELGASMYLREMLGREDGAPPPVDLAVERRHGAFVRELIRTDRARTVHDLSDGGLIAA
AAEMALASNVGVTLTIDGAPHAALFGEDQARYLIGTADPEAILSAAKKAGVPAAVVGRAGGEAVAVEGLFTLPLAELRQA
HEGWMPAYMGD
>Mature_730_residues
SAQPAKTMAEKAAEYGLKPEEYDLIVKRLNREPNDVELGVFSVMWSEHCSYKSSRKHLVKFPTKGPRVIQGPGENAGVID
IGDGQACIFKMESHNHPSYIEPYQGAATGVGGIMRDVFTMGARPVALLNALRFGDPAHPKTKRLVSGVVSGIGGYGNCVG
VPTVAGETNFHRGYDGNILVNAMCVGLADADKIFYSAAPAPGLPVVYFGSKTGRDGIHGATMASAEFDDASEEKRPTVQV
GDPFAEKLLIEATLELMASGAVAAIQDMGAAGLTSSSVEMAGKGGVGIELDLDAVPQREEGMTAYEMMLSESQERMLAIL
KPGREADGHRIFQKWGLDAAVIGRTTDTGHIVLKHQGQVVCDVPLAPLSDDAPLYDRPWVAPEAAPRLDPADVPAPGDWK
AAVLKLMSAPDMASKRWIWEQYDRHVMADTLEDSATGADAGIVRVHGTRKALAVTSDCTPRYVQNDPYEGGKQAVAEAWR
NVTAVGALPIAITDNLNFGNPERPEIMGQIVRAIEGMAEACRELDFPVVSGNVSLYNETNGVAIPPTPTVGGVGLIEDYA
HRADFSNLAAGEALVLVGETQGELGASMYLREMLGREDGAPPPVDLAVERRHGAFVRELIRTDRARTVHDLSDGGLIAAA
AEMALASNVGVTLTIDGAPHAALFGEDQARYLIGTADPEAILSAAKKAGVPAAVVGRAGGEAVAVEGLFTLPLAELRQAH
EGWMPAYMGD

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=800, Percent_Identity=25.75, Blast_Score=119, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17553022, Length=544, Percent_Identity=22.2426470588235, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 77460; Mature: 77328

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQPAKTMAEKAAEYGLKPEEYDLIVKRLNREPNDVELGVFSVMWSEHCSYKSSRKHLV
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCEE
KFPTKGPRVIQGPGENAGVIDIGDGQACIFKMESHNHPSYIEPYQGAATGVGGIMRDVFT
ECCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
MGARPVALLNALRFGDPAHPKTKRLVSGVVSGIGGYGNCVGVPTVAGETNFHRGYDGNIL
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEECCCEECCCCCCCCCCCCCEE
VNAMCVGLADADKIFYSAAPAPGLPVVYFGSKTGRDGIHGATMASAEFDDASEEKRPTVQ
EEEEEECCCCHHHHEEECCCCCCCEEEEECCCCCCCCCCCCEECCCCCCCCCHHCCCEEE
VGDPFAEKLLIEATLELMASGAVAAIQDMGAAGLTSSSVEMAGKGGVGIELDLDAVPQRE
ECCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHCCCCCCCEEEEECCCCCCCC
EGMTAYEMMLSESQERMLAILKPGREADGHRIFQKWGLDAAVIGRTTDTGHIVLKHQGQV
CCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEEECCCE
VCDVPLAPLSDDAPLYDRPWVAPEAAPRLDPADVPAPGDWKAAVLKLMSAPDMASKRWIW
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYDRHVMADTLEDSATGADAGIVRVHGTRKALAVTSDCTPRYVQNDPYEGGKQAVAEAW
HHHCCHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
RNVTAVGALPIAITDNLNFGNPERPEIMGQIVRAIEGMAEACRELDFPVVSGNVSLYNET
HCEEEECEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECC
NGVAIPPTPTVGGVGLIEDYAHRADFSNLAAGEALVLVGETQGELGASMYLREMLGREDG
CCEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
APPPVDLAVERRHGAFVRELIRTDRARTVHDLSDGGLIAAAAEMALASNVGVTLTIDGAP
CCCCCCEEEECCCCHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
HAALFGEDQARYLIGTADPEAILSAAKKAGVPAAVVGRAGGEAVAVEGLFTLPLAELRQA
CEEEECCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCEEEECCCHHCCHHHHHHH
HEGWMPAYMGD
HCCCCCCCCCC
>Mature Secondary Structure 
SAQPAKTMAEKAAEYGLKPEEYDLIVKRLNREPNDVELGVFSVMWSEHCSYKSSRKHLV
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCEE
KFPTKGPRVIQGPGENAGVIDIGDGQACIFKMESHNHPSYIEPYQGAATGVGGIMRDVFT
ECCCCCCEEEECCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
MGARPVALLNALRFGDPAHPKTKRLVSGVVSGIGGYGNCVGVPTVAGETNFHRGYDGNIL
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEECCCEECCCCCCCCCCCCCEE
VNAMCVGLADADKIFYSAAPAPGLPVVYFGSKTGRDGIHGATMASAEFDDASEEKRPTVQ
EEEEEECCCCHHHHEEECCCCCCCEEEEECCCCCCCCCCCCEECCCCCCCCCHHCCCEEE
VGDPFAEKLLIEATLELMASGAVAAIQDMGAAGLTSSSVEMAGKGGVGIELDLDAVPQRE
ECCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHCCCCCCCEEEEECCCCCCCC
EGMTAYEMMLSESQERMLAILKPGREADGHRIFQKWGLDAAVIGRTTDTGHIVLKHQGQV
CCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEEECCCE
VCDVPLAPLSDDAPLYDRPWVAPEAAPRLDPADVPAPGDWKAAVLKLMSAPDMASKRWIW
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYDRHVMADTLEDSATGADAGIVRVHGTRKALAVTSDCTPRYVQNDPYEGGKQAVAEAW
HHHCCHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
RNVTAVGALPIAITDNLNFGNPERPEIMGQIVRAIEGMAEACRELDFPVVSGNVSLYNET
HCEEEECEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECC
NGVAIPPTPTVGGVGLIEDYAHRADFSNLAAGEALVLVGETQGELGASMYLREMLGREDG
CCEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
APPPVDLAVERRHGAFVRELIRTDRARTVHDLSDGGLIAAAAEMALASNVGVTLTIDGAP
CCCCCCEEEECCCCHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
HAALFGEDQARYLIGTADPEAILSAAKKAGVPAAVVGRAGGEAVAVEGLFTLPLAELRQA
CEEEECCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCEEEECCCHHCCHHHHHHH
HEGWMPAYMGD
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]