Click here to switch to the map view.

The map label for this gene is hsdR [H]

Identifier: 197104450

GI number: 197104450

Start: 1089242

End: 1091689

Strand: Reverse

Name: hsdR [H]

Synonym: PHZ_c0984

Alternate gene names: 197104450

Gene position: 1091689-1089242 (Counterclockwise)

Preceding gene: 197104454

Following gene: 197104449

Centisome position: 27.32

GC content: 63.85

Gene sequence:

>2448_bases
GTGGATAAGCGCGCGCTGTCGGAGCGCGACATCTGCACGAAGTTCATCACGCCTGCGCTGCGTCGCGCCGGGTGGGATGA
GCAGACTCAGTTCCTTGAGGAAGTCTCCTTCACCAAGGGCCGCATCACGGTTCGCGGTAAGCTCGTCTCCCGGGGCAAGG
CCAAACGCGCCGACTACATCCTCTACATCAAGCCGAACGTTCCGATCGGCATCATCGAGGCCAAGGACAACCGGCACGCC
GTCGGCGACGGGATGCAACAGGCGCTGGAGTACGCCGACATCCTGAACCTGCCGTTCGCCTTCTCTTCCAATGGCGATGG
CTTCGTCTTCCATGACCGCACGGGCGCCGCCGACCAGAAGGAAACTGACGTCGCGCTGGACGCCTTCCCGACGCGAGCCG
AACTTTGGAGGCGCTACTGCGCCTGGAAAGGGCTGACGCCGGAGGCCGAGGAGGTCGTCCTTCAGGACTACTTCGACGAC
GGGAGCGGCAAGGCTCCTCGCTACTATCAGGTCAATGCGGTCAACGCGGCCGTCGAAGCCATCGCCAAGGGCCGCGACCG
CGTACTGCTCGTGATGGCGACCGGCACGGGCAAGACCTACACCGCCTTCCAGATCATCTGGCGGCTGTGGAAGGCCGGCC
AGAAGAAGCGGATCCTTTTCCTGGCCGACCGGAACATCCTGGTCGATCAGACCATGGTTAACGACTTCCGCCCATTCGGG
CCGGCGATGGCCAAGCTGTCCACCAAGTCCAAGACCATCGAGCGTGCGGACGGCACCGAGGTCGATCTCACGCTCGCGAT
GGACAAGCGCCGTCGCGTCGACACGGCTTTCGAAATCTACCTCGGCCTCTATCAGGCGATCACCGGACCCGAGGAGCGGC
AGAAGATCTTCAAGGACTTCTCCCCCGGCTTCTTCGATCTGATCGTGATCGACGAGTGTCATAGAGGCAGCGCAGCCGAC
GATGCGGCCTGGCGCGAAATCCTGGAGCACTTCTCGGGCGCCACCCAGATCGGCCTGACCGCCACGCCCAAGGAGACGAC
CTACGTCTCGAACAGCGCCTACTTCGGCGAGCCGGTCTACACCTACTCCCTGCGCCAAGGCATCGCCGACGGCTTCCTCG
CTCCCTACAAGGTGATCAAGGTCCACATCGACCGTGACGTCGAAGGCTACCGGCCCGAGAAGGGTCAGGTCGACCGCGAC
GGAAACGAGATCGAGGACCGAATCTACAATCGCCGGGACTTCGACCGAACTCTGGTGCTGGACGACCGGACCAAGCTGGT
CGCGGCCAAGGTCACCGAGTTCCTGAAGGAGAGCGGCGATCGCTTCCAGAAGACCATCGTCTTCTGCGTCGACGAGGAGC
ACGCGGCTCGCATGCGTCAAGCCCTCGTCAACGAGAACAAGGACCTGTGCGACGCCAATCACCGTTACGTCATGCGGATC
ACCGGCAGCGACAAGGACGGCCTCGACCAGCTGGGCAACTTCATCGATCCCGAGTCGCGCTATCCGGTGATCGTCACGAC
CTCGCGTCTGCTCTCAACCGGCGTGGATGCCCAGACCTGCCGCCTGATCGTGCTGGACCGCGCCGTAGGCTCGATGACGG
AATTCAAGCAGATCGTCGGCCGCGGCACTCGTGTGAACGAGGACGCCCGCAAATTCTACTTCACGCTCATGGACTTCCGG
GGCGCCACGGATCATTTCGCCGATCCCGAGTTCGACGGCGATCCCGTCCAAATCTACGAGCCGGGCCCTGGACAGCCAGT
CTCGCCTCCTGACGACCTGCCGCCAGGCGGGGAGATCAGCGAGGAGGGCGAGGAGTTCACGGGCGATCCCGGGGTGATCA
TCCGCGATCCCTGGAACACGGGTAAGGGTGGCGGCGATCCCGTCCGCAAGGTCTACGTCGACGGCGTCGGAGCGCATATC
ATCGCGGAGCGCGTCGAGTATCTCGACGCAAACGGCAAGCTCGTCACCGAATCTCTCCGCGACTACACCAAAACGGCCCT
TCGCAAGCGCTACGCGAGCCTGGATGAGTTCCTGAAGCGCTGGAACACGGAGGCGCGCAAGCAGGCCATCGTCGACGAGC
TGGAGGCCGAGGGGCTGCCGCTGGACGTCGTGGGACACGAGCTGGGCAAGGACCTCGACCCCTTCGATCTCATCTGCCAC
GTCGCCTTCGACGCCAAGCCGCTCACCCGGCGCGAGCGAGCCGAAGGCGTCAAGAAGCGGGACGTCTTCACGAAATACGG
GCCGCAGGCGCGCGCCGTACTGGATGGGCTCCTGGCGAAGTACGCCGACGAAGGCGTGCTCAACCTGGACGACCCCAGCG
TCCTGCGGATCCCGCCATTCACCCAAATGGGCAGCGTCGTCCAGCTCATCCGGGCATTTGGCGGCAAACAGGGTTTCGAT
CGCGCCGTCCACGATTTGCAGGACGCGCTCTACCAGGACGTCGGTTGA

Upstream 100 bases:

>100_bases
CGGCTGCCGGTTGACGACATGGCTCCGCTCGCGCTGAAGTCGCGGCGGGGGAGTGCTTTGATCACCAGCTGCAGTTCTGC
ATCGATGACGGACGGCCGCG

Downstream 100 bases:

>100_bases
CGATGCCGTGGTTCGGAGCGCGTGAACTTGCCGACCACGCATTCATCGACCGTCTACAGCGGCACCGGCGTGAGTTCCTG
GACTCTGACTCTCTTGAGGC

Product: type I restriction-modification system, R subunit

Products: NA

Alternate protein names: R.EcoEI [H]

Number of amino acids: Translated: 815; Mature: 815

Protein sequence:

>815_residues
MDKRALSERDICTKFITPALRRAGWDEQTQFLEEVSFTKGRITVRGKLVSRGKAKRADYILYIKPNVPIGIIEAKDNRHA
VGDGMQQALEYADILNLPFAFSSNGDGFVFHDRTGAADQKETDVALDAFPTRAELWRRYCAWKGLTPEAEEVVLQDYFDD
GSGKAPRYYQVNAVNAAVEAIAKGRDRVLLVMATGTGKTYTAFQIIWRLWKAGQKKRILFLADRNILVDQTMVNDFRPFG
PAMAKLSTKSKTIERADGTEVDLTLAMDKRRRVDTAFEIYLGLYQAITGPEERQKIFKDFSPGFFDLIVIDECHRGSAAD
DAAWREILEHFSGATQIGLTATPKETTYVSNSAYFGEPVYTYSLRQGIADGFLAPYKVIKVHIDRDVEGYRPEKGQVDRD
GNEIEDRIYNRRDFDRTLVLDDRTKLVAAKVTEFLKESGDRFQKTIVFCVDEEHAARMRQALVNENKDLCDANHRYVMRI
TGSDKDGLDQLGNFIDPESRYPVIVTTSRLLSTGVDAQTCRLIVLDRAVGSMTEFKQIVGRGTRVNEDARKFYFTLMDFR
GATDHFADPEFDGDPVQIYEPGPGQPVSPPDDLPPGGEISEEGEEFTGDPGVIIRDPWNTGKGGGDPVRKVYVDGVGAHI
IAERVEYLDANGKLVTESLRDYTKTALRKRYASLDEFLKRWNTEARKQAIVDELEAEGLPLDVVGHELGKDLDPFDLICH
VAFDAKPLTRRERAEGVKKRDVFTKYGPQARAVLDGLLAKYADEGVLNLDDPSVLRIPPFTQMGSVVQLIRAFGGKQGFD
RAVHDLQDALYQDVG

Sequences:

>Translated_815_residues
MDKRALSERDICTKFITPALRRAGWDEQTQFLEEVSFTKGRITVRGKLVSRGKAKRADYILYIKPNVPIGIIEAKDNRHA
VGDGMQQALEYADILNLPFAFSSNGDGFVFHDRTGAADQKETDVALDAFPTRAELWRRYCAWKGLTPEAEEVVLQDYFDD
GSGKAPRYYQVNAVNAAVEAIAKGRDRVLLVMATGTGKTYTAFQIIWRLWKAGQKKRILFLADRNILVDQTMVNDFRPFG
PAMAKLSTKSKTIERADGTEVDLTLAMDKRRRVDTAFEIYLGLYQAITGPEERQKIFKDFSPGFFDLIVIDECHRGSAAD
DAAWREILEHFSGATQIGLTATPKETTYVSNSAYFGEPVYTYSLRQGIADGFLAPYKVIKVHIDRDVEGYRPEKGQVDRD
GNEIEDRIYNRRDFDRTLVLDDRTKLVAAKVTEFLKESGDRFQKTIVFCVDEEHAARMRQALVNENKDLCDANHRYVMRI
TGSDKDGLDQLGNFIDPESRYPVIVTTSRLLSTGVDAQTCRLIVLDRAVGSMTEFKQIVGRGTRVNEDARKFYFTLMDFR
GATDHFADPEFDGDPVQIYEPGPGQPVSPPDDLPPGGEISEEGEEFTGDPGVIIRDPWNTGKGGGDPVRKVYVDGVGAHI
IAERVEYLDANGKLVTESLRDYTKTALRKRYASLDEFLKRWNTEARKQAIVDELEAEGLPLDVVGHELGKDLDPFDLICH
VAFDAKPLTRRERAEGVKKRDVFTKYGPQARAVLDGLLAKYADEGVLNLDDPSVLRIPPFTQMGSVVQLIRAFGGKQGFD
RAVHDLQDALYQDVG
>Mature_815_residues
MDKRALSERDICTKFITPALRRAGWDEQTQFLEEVSFTKGRITVRGKLVSRGKAKRADYILYIKPNVPIGIIEAKDNRHA
VGDGMQQALEYADILNLPFAFSSNGDGFVFHDRTGAADQKETDVALDAFPTRAELWRRYCAWKGLTPEAEEVVLQDYFDD
GSGKAPRYYQVNAVNAAVEAIAKGRDRVLLVMATGTGKTYTAFQIIWRLWKAGQKKRILFLADRNILVDQTMVNDFRPFG
PAMAKLSTKSKTIERADGTEVDLTLAMDKRRRVDTAFEIYLGLYQAITGPEERQKIFKDFSPGFFDLIVIDECHRGSAAD
DAAWREILEHFSGATQIGLTATPKETTYVSNSAYFGEPVYTYSLRQGIADGFLAPYKVIKVHIDRDVEGYRPEKGQVDRD
GNEIEDRIYNRRDFDRTLVLDDRTKLVAAKVTEFLKESGDRFQKTIVFCVDEEHAARMRQALVNENKDLCDANHRYVMRI
TGSDKDGLDQLGNFIDPESRYPVIVTTSRLLSTGVDAQTCRLIVLDRAVGSMTEFKQIVGRGTRVNEDARKFYFTLMDFR
GATDHFADPEFDGDPVQIYEPGPGQPVSPPDDLPPGGEISEEGEEFTGDPGVIIRDPWNTGKGGGDPVRKVYVDGVGAHI
IAERVEYLDANGKLVTESLRDYTKTALRKRYASLDEFLKRWNTEARKQAIVDELEAEGLPLDVVGHELGKDLDPFDLICH
VAFDAKPLTRRERAEGVKKRDVFTKYGPQARAVLDGLLAKYADEGVLNLDDPSVLRIPPFTQMGSVVQLIRAFGGKQGFD
RAVHDLQDALYQDVG

Specific function: The EcoEI enzyme recognizes 5'-GAGN(7)ATGC-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG4096

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI226510991, Length=652, Percent_Identity=28.9877300613497, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1788511, Length=446, Percent_Identity=25.3363228699552, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR013670
- InterPro:   IPR007409 [H]

Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 91535; Mature: 91535

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRALSERDICTKFITPALRRAGWDEQTQFLEEVSFTKGRITVRGKLVSRGKAKRADYI
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCCCEE
LYIKPNVPIGIIEAKDNRHAVGDGMQQALEYADILNLPFAFSSNGDGFVFHDRTGAADQK
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCCCCCC
ETDVALDAFPTRAELWRRYCAWKGLTPEAEEVVLQDYFDDGSGKAPRYYQVNAVNAAVEA
CCCEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHH
IAKGRDRVLLVMATGTGKTYTAFQIIWRLWKAGQKKRILFLADRNILVDQTMVNDFRPFG
HHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEECHHHHHHCCCCC
PAMAKLSTKSKTIERADGTEVDLTLAMDKRRRVDTAFEIYLGLYQAITGPEERQKIFKDF
HHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
SPGFFDLIVIDECHRGSAADDAAWREILEHFSGATQIGLTATPKETTYVSNSAYFGEPVY
CCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEECEEECCCCCEEECCCCCCCCCEE
TYSLRQGIADGFLAPYKVIKVHIDRDVEGYRPEKGQVDRDGNEIEDRIYNRRDFDRTLVL
EHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEE
DDRTKLVAAKVTEFLKESGDRFQKTIVFCVDEEHAARMRQALVNENKDLCDANHRYVMRI
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEEE
TGSDKDGLDQLGNFIDPESRYPVIVTTSRLLSTGVDAQTCRLIVLDRAVGSMTEFKQIVG
ECCCCCCHHHHCCCCCCCCCCCEEEEEHHHHHCCCCHHHEEEEEEEHHHCCHHHHHHHHC
RGTRVNEDARKFYFTLMDFRGATDHFADPEFDGDPVQIYEPGPGQPVSPPDDLPPGGEIS
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
EEGEEFTGDPGVIIRDPWNTGKGGGDPVRKVYVDGVGAHIIAERVEYLDANGKLVTESLR
CCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHH
DYTKTALRKRYASLDEFLKRWNTEARKQAIVDELEAEGLPLDVVGHELGKDLDPFDLICH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHEE
VAFDAKPLTRRERAEGVKKRDVFTKYGPQARAVLDGLLAKYADEGVLNLDDPSVLRIPPF
EECCCCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCCCCEEECCCC
TQMGSVVQLIRAFGGKQGFDRAVHDLQDALYQDVG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKRALSERDICTKFITPALRRAGWDEQTQFLEEVSFTKGRITVRGKLVSRGKAKRADYI
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCCCEE
LYIKPNVPIGIIEAKDNRHAVGDGMQQALEYADILNLPFAFSSNGDGFVFHDRTGAADQK
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCCCCCC
ETDVALDAFPTRAELWRRYCAWKGLTPEAEEVVLQDYFDDGSGKAPRYYQVNAVNAAVEA
CCCEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHH
IAKGRDRVLLVMATGTGKTYTAFQIIWRLWKAGQKKRILFLADRNILVDQTMVNDFRPFG
HHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEECHHHHHHCCCCC
PAMAKLSTKSKTIERADGTEVDLTLAMDKRRRVDTAFEIYLGLYQAITGPEERQKIFKDF
HHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
SPGFFDLIVIDECHRGSAADDAAWREILEHFSGATQIGLTATPKETTYVSNSAYFGEPVY
CCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEECEEECCCCCEEECCCCCCCCCEE
TYSLRQGIADGFLAPYKVIKVHIDRDVEGYRPEKGQVDRDGNEIEDRIYNRRDFDRTLVL
EHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEE
DDRTKLVAAKVTEFLKESGDRFQKTIVFCVDEEHAARMRQALVNENKDLCDANHRYVMRI
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEEE
TGSDKDGLDQLGNFIDPESRYPVIVTTSRLLSTGVDAQTCRLIVLDRAVGSMTEFKQIVG
ECCCCCCHHHHCCCCCCCCCCCEEEEEHHHHHCCCCHHHEEEEEEEHHHCCHHHHHHHHC
RGTRVNEDARKFYFTLMDFRGATDHFADPEFDGDPVQIYEPGPGQPVSPPDDLPPGGEIS
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
EEGEEFTGDPGVIIRDPWNTGKGGGDPVRKVYVDGVGAHIIAERVEYLDANGKLVTESLR
CCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHH
DYTKTALRKRYASLDEFLKRWNTEARKQAIVDELEAEGLPLDVVGHELGKDLDPFDLICH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHEE
VAFDAKPLTRRERAEGVKKRDVFTKYGPQARAVLDGLLAKYADEGVLNLDDPSVLRIPPF
EECCCCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCCCCEEECCCC
TQMGSVVQLIRAFGGKQGFDRAVHDLQDALYQDVG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412658 [H]