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The map label for this gene is flp [H]

Identifier: 197104329

GI number: 197104329

Start: 955897

End: 958092

Strand: Reverse

Name: flp [H]

Synonym: PHZ_c0863

Alternate gene names: 197104329

Gene position: 958092-955897 (Counterclockwise)

Preceding gene: 197104330

Following gene: 197104328

Centisome position: 23.97

GC content: 74.0

Gene sequence:

>2196_bases
ATGCGGTGCGGACTGAAGACGGCCCTCGCGGGCCTGGCGATGCTCATCCTCGGCCCCGCCGCGGCCGCGCAGGAGGCCGA
GCCCTCGTCATCCCCGCCGCCGGCGATCGCCGCCGCCGCCCTGCCCGACGCGCCGGTCCCCTACACCCAGATCCGTCCGA
AACGGCCCCAGCCCAAGGCGCGCCCGCAGGCGACCGCCCCGCAATCCGTCGCGGGCCAGGCGGCCGCCGCCCAGCCCGCG
GCGCCCGCCGTCGCCGGAGCGGCGGACGTGGTCCCCGGCCTGCCCGTCCAGGCCACCGGCGCGCGGCTGTCGCCGGGCGA
GACCATTCCCACCGCCGAGCTGGAGGCCTTCGTCGACGGCTGGGTGCGCGACGCCATGGCCCGCGAGCATGTCGCCGGGG
CGGCGGTCTCGATCGTCCAGAACGGCCGGGTGGTCCTGAAGAAGGGCTACGGCTTCGCCGACCTCAACCCGCGAAAGGCC
GTGGACCCCGACCGGACGCTGTTCCGCATCGGCTCGATCTCCAAGACCTTCACCTGGATCCTGGCGATGAACGAGGTCGA
GAGGGGGCGGATGGCGCTCGACCAGCCGATCAACCGCTACCTGCCCGAGAAGACCCGGGTGCGCGGCGAGGGCTACCGCC
GGCCGGTCACCCTGAAGACCCTGATGGACCACTCGCCGGGCTTCGAGGACCGGGCCATGGGCCAGCTCTTCGAACGCGAC
GCCGACCGCATCCGCCCCCTCGACCTCTACCTGCGGCAGGAGCGGCCCCGGCGCGTGCGCGCGTCGGGCGTGGCGTCCAG
CTACTCCAACTACGGCACGGGGCTGGCGGGACTGGCGGTCGCCAACCTCAACCGCAAGCCGTTCGAGGACCTGGTCGAGG
ACGAGCTGCTCACGCCGCTGGGCATGAGCCGCACCACGTTCCGCGAGCCGCGTCCCGAGCGGCGCGGCCTGCCCGCGCCG
ATGCCGGCGGACCTGCAGGACGACGTGGCCCGCGGCTATTGGTGGCGCGGCGGAGCCTTCAAGGTGCGTCCCTACGAGTA
CATCGGCCAGATCGCCCCGGCCGGGTCGGCCTCGTCGACCGCCGGCGACATGGCGCGCTACATGCTGGCGCTGCTGGGCG
ACGGATCCTGGAATGGCGCGACCATCTACGGCCCCCGCGCGGCGCGGGCGTTCCGCCAGCCGATCCAGGCCACCGCGCCG
GGGATCAACGGCTGGGCCCACGGCTTCATCGTCTACGGTCTGCCGGGGGGCTATCGCGGCTACGGCCACGACGGGGCGAC
CATCGCCTTCCATTCCAGCATGGTGGTGGCGCCGCAGCTGGGCCTCGGCGTCTTCATCACGACCAACAGCGACGACGGCC
ACGAGCTGAGCGGCCGGTTCGCCGAGGCCGTCGTGCGCCAGTTCTACGCCGCCCCGGTGACGTTCCCGCGCCCCGGCTCG
GCCGAGCTGCTGGCGGCCCGCGGGGCGTTCGAGGGCTACTACGTCACCAGCCGCCGGGCCCATGGCGGGCTGGAGGGCTT
CGTCGGCCTGATGATCGGCGGGACGCAGGCGCGCGTGACGCCGGAGGGCCGGCTGGTCACCGGCTCGGGCGACGAGCTGC
GGACCTGGGTCCCGGAAGGCCCGGTCCGCGAGGGCCGGTTCATCGCCGCCGACGGCGACGAGCGGCTGGCCTTCCGGATG
AAGAACGGCCGCGCCGTCAGCTTCCGCGACGCCTTCAACGCCGCCCAGATGCAGCGGGCGGCCTGGTGGATGCACCCGCT
GCTCCTGGGCGCCCTGGCGGGCCTGACCGGCCTGGCCGCCATCGCGACCCTGCTGGGCGTCTTCCTGCGCAACCGGCGCG
ACTTCCGCGAAAGCCAGATCCAGGCGCGGGCCGCGCTCACCCAGAACATCCAGGCCGGGCTGTGGCTCGCCGCCTTCGCC
CTGCTGGCGGCGTGGGGCATGCAGACGGCCGACCTCGCCAAGGTGTTCTTCGACTGGCCGGGGGCTCTGCTGATCACCGC
ATCGGCCTGCGCCCTCGTCGCCGCGGCCCTGACCCTGGTCACCGCGGCCGCGCTGCCGGCGGTCTGGCAGGGCGGCCGGC
GGGTCGAATCGTGGACCGGGACCCGCAAGGCGTTCTTCACCGTCACTGTGCTGGTCTATGCCGCTTTCTCGGTGGTGCTG
GGCCTCTGGGGCCTCCTGTCCCCCTGGAGCGGCTGA

Upstream 100 bases:

>100_bases
TGCCTCTCTACGGCTTCCCCTAGCATGGCCCCGCTTTGAGAGACTCGTCTTTCCGCCCTACAACCGGATCGATGGTGGGG
TGGAGGTTGGGGAGCTCTCC

Downstream 100 bases:

>100_bases
ACTCCTTAAACCCGCGTTTACCAACGACTGGGTAATTCCTGCCTAGTGGAGGGCGGGAATGATTTGCCGCGCGCCCTCCG
GAGTTGGGGGAAGGACGCCC

Product: beta-lactamase class C

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 731; Mature: 731

Protein sequence:

>731_residues
MRCGLKTALAGLAMLILGPAAAAQEAEPSSSPPPAIAAAALPDAPVPYTQIRPKRPQPKARPQATAPQSVAGQAAAAQPA
APAVAGAADVVPGLPVQATGARLSPGETIPTAELEAFVDGWVRDAMAREHVAGAAVSIVQNGRVVLKKGYGFADLNPRKA
VDPDRTLFRIGSISKTFTWILAMNEVERGRMALDQPINRYLPEKTRVRGEGYRRPVTLKTLMDHSPGFEDRAMGQLFERD
ADRIRPLDLYLRQERPRRVRASGVASSYSNYGTGLAGLAVANLNRKPFEDLVEDELLTPLGMSRTTFREPRPERRGLPAP
MPADLQDDVARGYWWRGGAFKVRPYEYIGQIAPAGSASSTAGDMARYMLALLGDGSWNGATIYGPRAARAFRQPIQATAP
GINGWAHGFIVYGLPGGYRGYGHDGATIAFHSSMVVAPQLGLGVFITTNSDDGHELSGRFAEAVVRQFYAAPVTFPRPGS
AELLAARGAFEGYYVTSRRAHGGLEGFVGLMIGGTQARVTPEGRLVTGSGDELRTWVPEGPVREGRFIAADGDERLAFRM
KNGRAVSFRDAFNAAQMQRAAWWMHPLLLGALAGLTGLAAIATLLGVFLRNRRDFRESQIQARAALTQNIQAGLWLAAFA
LLAAWGMQTADLAKVFFDWPGALLITASACALVAAALTLVTAAALPAVWQGGRRVESWTGTRKAFFTVTVLVYAAFSVVL
GLWGLLSPWSG

Sequences:

>Translated_731_residues
MRCGLKTALAGLAMLILGPAAAAQEAEPSSSPPPAIAAAALPDAPVPYTQIRPKRPQPKARPQATAPQSVAGQAAAAQPA
APAVAGAADVVPGLPVQATGARLSPGETIPTAELEAFVDGWVRDAMAREHVAGAAVSIVQNGRVVLKKGYGFADLNPRKA
VDPDRTLFRIGSISKTFTWILAMNEVERGRMALDQPINRYLPEKTRVRGEGYRRPVTLKTLMDHSPGFEDRAMGQLFERD
ADRIRPLDLYLRQERPRRVRASGVASSYSNYGTGLAGLAVANLNRKPFEDLVEDELLTPLGMSRTTFREPRPERRGLPAP
MPADLQDDVARGYWWRGGAFKVRPYEYIGQIAPAGSASSTAGDMARYMLALLGDGSWNGATIYGPRAARAFRQPIQATAP
GINGWAHGFIVYGLPGGYRGYGHDGATIAFHSSMVVAPQLGLGVFITTNSDDGHELSGRFAEAVVRQFYAAPVTFPRPGS
AELLAARGAFEGYYVTSRRAHGGLEGFVGLMIGGTQARVTPEGRLVTGSGDELRTWVPEGPVREGRFIAADGDERLAFRM
KNGRAVSFRDAFNAAQMQRAAWWMHPLLLGALAGLTGLAAIATLLGVFLRNRRDFRESQIQARAALTQNIQAGLWLAAFA
LLAAWGMQTADLAKVFFDWPGALLITASACALVAAALTLVTAAALPAVWQGGRRVESWTGTRKAFFTVTVLVYAAFSVVL
GLWGLLSPWSG
>Mature_731_residues
MRCGLKTALAGLAMLILGPAAAAQEAEPSSSPPPAIAAAALPDAPVPYTQIRPKRPQPKARPQATAPQSVAGQAAAAQPA
APAVAGAADVVPGLPVQATGARLSPGETIPTAELEAFVDGWVRDAMAREHVAGAAVSIVQNGRVVLKKGYGFADLNPRKA
VDPDRTLFRIGSISKTFTWILAMNEVERGRMALDQPINRYLPEKTRVRGEGYRRPVTLKTLMDHSPGFEDRAMGQLFERD
ADRIRPLDLYLRQERPRRVRASGVASSYSNYGTGLAGLAVANLNRKPFEDLVEDELLTPLGMSRTTFREPRPERRGLPAP
MPADLQDDVARGYWWRGGAFKVRPYEYIGQIAPAGSASSTAGDMARYMLALLGDGSWNGATIYGPRAARAFRQPIQATAP
GINGWAHGFIVYGLPGGYRGYGHDGATIAFHSSMVVAPQLGLGVFITTNSDDGHELSGRFAEAVVRQFYAAPVTFPRPGS
AELLAARGAFEGYYVTSRRAHGGLEGFVGLMIGGTQARVTPEGRLVTGSGDELRTWVPEGPVREGRFIAADGDERLAFRM
KNGRAVSFRDAFNAAQMQRAAWWMHPLLLGALAGLTGLAAIATLLGVFLRNRRDFRESQIQARAALTQNIQAGLWLAAFA
LLAAWGMQTADLAKVFFDWPGALLITASACALVAAALTLVTAAALPAVWQGGRRVESWTGTRKAFFTVTVLVYAAFSVVL
GLWGLLSPWSG

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790593, Length=258, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786574, Length=335, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 78294; Mature: 78294

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCGLKTALAGLAMLILGPAAAAQEAEPSSSPPPAIAAAALPDAPVPYTQIRPKRPQPKA
CCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEECCCCCCCCCHHCCCCCCCCCCC
RPQATAPQSVAGQAAAAQPAAPAVAGAADVVPGLPVQATGARLSPGETIPTAELEAFVDG
CCCCCCCHHHCCCHHCCCCCCCHHCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
WVRDAMAREHVAGAAVSIVQNGRVVLKKGYGFADLNPRKAVDPDRTLFRIGSISKTFTWI
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHEEECCCCHHHEEEE
LAMNEVERGRMALDQPINRYLPEKTRVRGEGYRRPVTLKTLMDHSPGFEDRAMGQLFERD
EEHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEHHHHHCCCCCCCHHHHHHHHHHH
ADRIRPLDLYLRQERPRRVRASGVASSYSNYGTGLAGLAVANLNRKPFEDLVEDELLTPL
HHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHCCCC
GMSRTTFREPRPERRGLPAPMPADLQDDVARGYWWRGGAFKVRPYEYIGQIAPAGSASST
CCCCCCCCCCCCHHCCCCCCCCCCCHHHHHCCCEECCCEEEECCHHHHHCCCCCCCCCCH
AGDMARYMLALLGDGSWNGATIYGPRAARAFRQPIQATAPGINGWAHGFIVYGLPGGYRG
HHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCC
YGHDGATIAFHSSMVVAPQLGLGVFITTNSDDGHELSGRFAEAVVRQFYAAPVTFPRPGS
CCCCCCEEEEECCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
AELLAARGAFEGYYVTSRRAHGGLEGFVGLMIGGTQARVTPEGRLVTGSGDELRTWVPEG
CHHEEECCCCCCEEEECCCCCCCHHHHHHHEECCCEEEECCCCEEEECCCCCCEECCCCC
PVREGRFIAADGDERLAFRMKNGRAVSFRDAFNAAQMQRAAWWMHPLLLGALAGLTGLAA
CCCCCEEEEECCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATLLGVFLRNRRDFRESQIQARAALTQNIQAGLWLAAFALLAAWGMQTADLAKVFFDWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GALLITASACALVAAALTLVTAAALPAVWQGGRRVESWTGTRKAFFTVTVLVYAAFSVVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHH
GLWGLLSPWSG
HHHHHCCCCCC
>Mature Secondary Structure
MRCGLKTALAGLAMLILGPAAAAQEAEPSSSPPPAIAAAALPDAPVPYTQIRPKRPQPKA
CCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEECCCCCCCCCHHCCCCCCCCCCC
RPQATAPQSVAGQAAAAQPAAPAVAGAADVVPGLPVQATGARLSPGETIPTAELEAFVDG
CCCCCCCHHHCCCHHCCCCCCCHHCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
WVRDAMAREHVAGAAVSIVQNGRVVLKKGYGFADLNPRKAVDPDRTLFRIGSISKTFTWI
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHEEECCCCHHHEEEE
LAMNEVERGRMALDQPINRYLPEKTRVRGEGYRRPVTLKTLMDHSPGFEDRAMGQLFERD
EEHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEHHHHHCCCCCCCHHHHHHHHHHH
ADRIRPLDLYLRQERPRRVRASGVASSYSNYGTGLAGLAVANLNRKPFEDLVEDELLTPL
HHHCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHCCCC
GMSRTTFREPRPERRGLPAPMPADLQDDVARGYWWRGGAFKVRPYEYIGQIAPAGSASST
CCCCCCCCCCCCHHCCCCCCCCCCCHHHHHCCCEECCCEEEECCHHHHHCCCCCCCCCCH
AGDMARYMLALLGDGSWNGATIYGPRAARAFRQPIQATAPGINGWAHGFIVYGLPGGYRG
HHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCC
YGHDGATIAFHSSMVVAPQLGLGVFITTNSDDGHELSGRFAEAVVRQFYAAPVTFPRPGS
CCCCCCEEEEECCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
AELLAARGAFEGYYVTSRRAHGGLEGFVGLMIGGTQARVTPEGRLVTGSGDELRTWVPEG
CHHEEECCCCCCEEEECCCCCCCHHHHHHHEECCCEEEECCCCEEEECCCCCCEECCCCC
PVREGRFIAADGDERLAFRMKNGRAVSFRDAFNAAQMQRAAWWMHPLLLGALAGLTGLAA
CCCCCEEEEECCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATLLGVFLRNRRDFRESQIQARAALTQNIQAGLWLAAFALLAAWGMQTADLAKVFFDWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GALLITASACALVAAALTLVTAAALPAVWQGGRRVESWTGTRKAFFTVTVLVYAAFSVVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHH
GLWGLLSPWSG
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA