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The map label for this gene is 197104218

Identifier: 197104218

GI number: 197104218

Start: 826581

End: 827723

Strand: Reverse

Name: 197104218

Synonym: PHZ_c0752

Alternate gene names: NA

Gene position: 827723-826581 (Counterclockwise)

Preceding gene: 197104219

Following gene: 197104217

Centisome position: 20.71

GC content: 71.3

Gene sequence:

>1143_bases
ATGCCGCAGCCGTTCGAAGTGTCATGGAGCGCCGCGGACGTGGCCGCGGTGCTGGACCAGGTGCGGGCCTACCCCTGGCC
GCCGGCGCCGGCGGTCCCCGACGGCTGGGCCTACGGCTGCGACGGCGGCTACCTGCGGAGCCTGTGCGAGCACTGGACCG
GCGCCTGGGACTGGCGCGCGGCCGTCGCCGAGCTGAACCGGTTCCCGCAGTTCACCGCCAGGGTGGAGGACTTCGACCTG
CACTTCGTGCACGTGGTCGGCGAAGCGGGCGGCAAGCGGCCGCTGATCCTGACCCACGGGTGGCCCGGATCGCACTACGA
GTTCTGGGAGAGCATCGAGAAGCTGGCGTTCCCGAGCCGGTTCGGCGGCGATCCGGCCGACGCCTTCGACCTGGTGATCC
CGTCCCTGCCCGGCTTCGGATTCTCGTCGAAGCCCGAGCGCCCCATCGGCCAGCGCGCCACAGCCCGGCTGTTCAACGGG
CTGATGACCCAGGTGCTGGGCTACGACCGCTATCTCGCCCAGGGCGGCGACTGGGGCGGCCTCGTCACCTCGTGGCTGGG
CCGCGACCACGCCGCGCACGTGTCGGCCATCCACCTGAACATGATCGGCTTCCGCCCGGACGGGCCGCCGCAGTCGGACG
CCGAGGTCGCCTGGATCCAGCGCCAGCAGGCGATGATGGACGTGATGGGCGCCTACTTCCGCCTGCAGGCCTCCAAGCCC
CAGTCGATCGCCTGGATGGCGGCGGGCAACCCGGTGGGCCAGGCCGCCTGGATCGCCGAACGCTTCCACGACTGGGCCGA
CCTGCGGGAGAAATCCCTCGACGAGGCCTTTCCCAAGGACCGGCTGCTGACCAACATCATGCTCTACGTGATGACCGGCA
GCTTCACGACGGGCGCCTGGTACTACCGGGGCCTGATCGAGGAAGGCGGCGTGTCCCTTCCGGCGGGCGAGCGCTGCGAG
ACGCCGACCGCCTTCGCCAACTTCCCCGGCGAGCCGCTCTACACCGCCCCGCCGCGGAGCTGGGCCGAGCGGGCCTACAA
CATCGTCCGCTGGACTGAGATGCCGCGCGGCGGCCACTTCGCGGCGATGGAGGAGCCGGACCTGTTCGTGGACGAGGTCA
GGGCTTGGGCGCGGGCGCTCTGA

Upstream 100 bases:

>100_bases
GGCAATACCTGTCATGGCCGCCCCCCAGCTTCCGGCGCGGAGCTTGACCGCCGTCGCGTCATCCGTCGAGCCTCGCCGCA
CAGCTTAGGAAGGAAGCCCC

Downstream 100 bases:

>100_bases
GCGGCTAAAGGGCGGGCATGAGCCACGCCCGCTACGACTTCGCCTCGGACAACACCGCGCCCGCCGCGCCCGAGGCGCTG
GAGGCGCTCGCCGCCGCCAA

Product: epoxide hydrolase

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MPQPFEVSWSAADVAAVLDQVRAYPWPPAPAVPDGWAYGCDGGYLRSLCEHWTGAWDWRAAVAELNRFPQFTARVEDFDL
HFVHVVGEAGGKRPLILTHGWPGSHYEFWESIEKLAFPSRFGGDPADAFDLVIPSLPGFGFSSKPERPIGQRATARLFNG
LMTQVLGYDRYLAQGGDWGGLVTSWLGRDHAAHVSAIHLNMIGFRPDGPPQSDAEVAWIQRQQAMMDVMGAYFRLQASKP
QSIAWMAAGNPVGQAAWIAERFHDWADLREKSLDEAFPKDRLLTNIMLYVMTGSFTTGAWYYRGLIEEGGVSLPAGERCE
TPTAFANFPGEPLYTAPPRSWAERAYNIVRWTEMPRGGHFAAMEEPDLFVDEVRAWARAL

Sequences:

>Translated_380_residues
MPQPFEVSWSAADVAAVLDQVRAYPWPPAPAVPDGWAYGCDGGYLRSLCEHWTGAWDWRAAVAELNRFPQFTARVEDFDL
HFVHVVGEAGGKRPLILTHGWPGSHYEFWESIEKLAFPSRFGGDPADAFDLVIPSLPGFGFSSKPERPIGQRATARLFNG
LMTQVLGYDRYLAQGGDWGGLVTSWLGRDHAAHVSAIHLNMIGFRPDGPPQSDAEVAWIQRQQAMMDVMGAYFRLQASKP
QSIAWMAAGNPVGQAAWIAERFHDWADLREKSLDEAFPKDRLLTNIMLYVMTGSFTTGAWYYRGLIEEGGVSLPAGERCE
TPTAFANFPGEPLYTAPPRSWAERAYNIVRWTEMPRGGHFAAMEEPDLFVDEVRAWARAL
>Mature_379_residues
PQPFEVSWSAADVAAVLDQVRAYPWPPAPAVPDGWAYGCDGGYLRSLCEHWTGAWDWRAAVAELNRFPQFTARVEDFDLH
FVHVVGEAGGKRPLILTHGWPGSHYEFWESIEKLAFPSRFGGDPADAFDLVIPSLPGFGFSSKPERPIGQRATARLFNGL
MTQVLGYDRYLAQGGDWGGLVTSWLGRDHAAHVSAIHLNMIGFRPDGPPQSDAEVAWIQRQQAMMDVMGAYFRLQASKPQ
SIAWMAAGNPVGQAAWIAERFHDWADLREKSLDEAFPKDRLLTNIMLYVMTGSFTTGAWYYRGLIEEGGVSLPAGERCET
PTAFANFPGEPLYTAPPRSWAERAYNIVRWTEMPRGGHFAAMEEPDLFVDEVRAWARAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=409, Percent_Identity=31.5403422982885, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI209862837, Length=409, Percent_Identity=31.5403422982885, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17564944, Length=373, Percent_Identity=32.4396782841823, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI193207462, Length=361, Percent_Identity=26.5927977839335, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI20130139, Length=389, Percent_Identity=30.3341902313625, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24655327, Length=407, Percent_Identity=28.009828009828, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI19922580, Length=379, Percent_Identity=27.7044854881267, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 42408; Mature: 42277

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPFEVSWSAADVAAVLDQVRAYPWPPAPAVPDGWAYGCDGGYLRSLCEHWTGAWDWRA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCHHHH
AVAELNRFPQFTARVEDFDLHFVHVVGEAGGKRPLILTHGWPGSHYEFWESIEKLAFPSR
HHHHHHHCCHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHCCHH
FGGDPADAFDLVIPSLPGFGFSSKPERPIGQRATARLFNGLMTQVLGYDRYLAQGGDWGG
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LVTSWLGRDHAAHVSAIHLNMIGFRPDGPPQSDAEVAWIQRQQAMMDVMGAYFRLQASKP
HHHHHHCCCHHHHEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCC
QSIAWMAAGNPVGQAAWIAERFHDWADLREKSLDEAFPKDRLLTNIMLYVMTGSFTTGAW
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHH
YYRGLIEEGGVSLPAGERCETPTAFANFPGEPLYTAPPRSWAERAYNIVRWTEMPRGGHF
HHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCC
AAMEEPDLFVDEVRAWARAL
CCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PQPFEVSWSAADVAAVLDQVRAYPWPPAPAVPDGWAYGCDGGYLRSLCEHWTGAWDWRA
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCHHHH
AVAELNRFPQFTARVEDFDLHFVHVVGEAGGKRPLILTHGWPGSHYEFWESIEKLAFPSR
HHHHHHHCCHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHCCHH
FGGDPADAFDLVIPSLPGFGFSSKPERPIGQRATARLFNGLMTQVLGYDRYLAQGGDWGG
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LVTSWLGRDHAAHVSAIHLNMIGFRPDGPPQSDAEVAWIQRQQAMMDVMGAYFRLQASKP
HHHHHHCCCHHHHEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCC
QSIAWMAAGNPVGQAAWIAERFHDWADLREKSLDEAFPKDRLLTNIMLYVMTGSFTTGAW
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHH
YYRGLIEEGGVSLPAGERCETPTAFANFPGEPLYTAPPRSWAERAYNIVRWTEMPRGGHF
HHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCC
AAMEEPDLFVDEVRAWARAL
CCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]