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The map label for this gene is ltaE [H]

Identifier: 197104217

GI number: 197104217

Start: 825550

End: 826563

Strand: Reverse

Name: ltaE [H]

Synonym: PHZ_c0751

Alternate gene names: 197104217

Gene position: 826563-825550 (Counterclockwise)

Preceding gene: 197104218

Following gene: 197104216

Centisome position: 20.68

GC content: 72.88

Gene sequence:

>1014_bases
ATGAGCCACGCCCGCTACGACTTCGCCTCGGACAACACCGCGCCCGCCGCGCCCGAGGCGCTGGAGGCGCTCGCCGCCGC
CAACACCGGCTTCACCTCGGGCTACGGGACCGATCCCGTCAGCGCCAAGGCCGCCGACCTGGTGCGCGAGATGCTGGACG
CCGACGCCGAGGTGCGGTTCGTCGCCTCGGGCACCGCCGCCAACGCCGTCGCCCTGGCGGCCCTGTGCCGGCCCTTCGAG
GCGGTGCTGGCCCACGAGCACGCCCACGTCTGCACCGACGAAACCGGCGCGCCGGGCTTCTTCGGCCAGGGACTGGGCCT
GATCCGCCTGCCCGGCGCCTCCGGCAGGATCGACCCGGCCGCCCTGGAGCAGCCCCTGTCGGCGCCCGACGTCTCCTACC
GCCAGCCGGCGGCGGCGCTCTCGCTGACCAACGCCACCGAGTACGGGACGGTCTATTCGGCGCACGAGCTCCGCGCTCTG
ATCGCGCCCGTGAAGGCCAAGGGCTACGGCGTGCACCTCGACGGCGCGCGGCTGGCCAACGCCGCCGCCGCCGGCTTCGA
CCTCAAAGCCATCAAGGAGCTGGGCGTCGACATCCTGGTGGTCGGCGGGACCAAGGCGGGGATGCCGCCTACCGAGGCGA
TCGTGATCTTCGACCGCGCCCTCGCCCGCCGCTTCGACGCGCGGCTGAAGCAGGCGGGGCAGCTGCCGTCCAAGGGCCGG
TTCTACGCCGCGCCGTTCATCGGCATGCTGGGCTCGGGCGCGTTCCTGCGCCATGCGGCCCACGCCAACGCCATGGCGCG
CAGGCTGGCCGAGCTCATGCCCTTCCCCGTCGTCCATCCGGTGGAGGCCAACGCGGTGTTCGTGGAGATGGACGATGCGG
CGCTGTCGCGGCTGCACGCGGCCGGCTGGTTCGCCTACCGCTTCCTGGACGGCTCGGTGCGGTTCATGTGCTCGTGGGCG
ACCACCGGTGAGTCGGTGGAACAACTGGCGGTTACACTCCGCGACCTGGCCTGA

Upstream 100 bases:

>100_bases
TGCCGCGCGGCGGCCACTTCGCGGCGATGGAGGAGCCGGACCTGTTCGTGGACGAGGTCAGGGCTTGGGCGCGGGCGCTC
TGAGCGGCTAAAGGGCGGGC

Downstream 100 bases:

>100_bases
AGGTCTTGAAAAGGGGTCACTTTTGCCGCGGGTTACCGGCAGGTGTGACATGTATGGCGCACTCGCCGCCCAAACTGGAA
CCAGACGCCCCATCGAACGC

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSHARYDFASDNTAPAAPEALEALAAANTGFTSGYGTDPVSAKAADLVREMLDADAEVRFVASGTAANAVALAALCRPFE
AVLAHEHAHVCTDETGAPGFFGQGLGLIRLPGASGRIDPAALEQPLSAPDVSYRQPAAALSLTNATEYGTVYSAHELRAL
IAPVKAKGYGVHLDGARLANAAAAGFDLKAIKELGVDILVVGGTKAGMPPTEAIVIFDRALARRFDARLKQAGQLPSKGR
FYAAPFIGMLGSGAFLRHAAHANAMARRLAELMPFPVVHPVEANAVFVEMDDAALSRLHAAGWFAYRFLDGSVRFMCSWA
TTGESVEQLAVTLRDLA

Sequences:

>Translated_337_residues
MSHARYDFASDNTAPAAPEALEALAAANTGFTSGYGTDPVSAKAADLVREMLDADAEVRFVASGTAANAVALAALCRPFE
AVLAHEHAHVCTDETGAPGFFGQGLGLIRLPGASGRIDPAALEQPLSAPDVSYRQPAAALSLTNATEYGTVYSAHELRAL
IAPVKAKGYGVHLDGARLANAAAAGFDLKAIKELGVDILVVGGTKAGMPPTEAIVIFDRALARRFDARLKQAGQLPSKGR
FYAAPFIGMLGSGAFLRHAAHANAMARRLAELMPFPVVHPVEANAVFVEMDDAALSRLHAAGWFAYRFLDGSVRFMCSWA
TTGESVEQLAVTLRDLA
>Mature_336_residues
SHARYDFASDNTAPAAPEALEALAAANTGFTSGYGTDPVSAKAADLVREMLDADAEVRFVASGTAANAVALAALCRPFEA
VLAHEHAHVCTDETGAPGFFGQGLGLIRLPGASGRIDPAALEQPLSAPDVSYRQPAAALSLTNATEYGTVYSAHELRALI
APVKAKGYGVHLDGARLANAAAAGFDLKAIKELGVDILVVGGTKAGMPPTEAIVIFDRALARRFDARLKQAGQLPSKGRF
YAAPFIGMLGSGAFLRHAAHANAMARRLAELMPFPVVHPVEANAVFVEMDDAALSRLHAAGWFAYRFLDGSVRFMCSWAT
TGESVEQLAVTLRDLA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=341, Percent_Identity=24.633431085044, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 35331; Mature: 35200

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHARYDFASDNTAPAAPEALEALAAANTGFTSGYGTDPVSAKAADLVREMLDADAEVRF
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
VASGTAANAVALAALCRPFEAVLAHEHAHVCTDETGAPGFFGQGLGLIRLPGASGRIDPA
EECCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCHH
ALEQPLSAPDVSYRQPAAALSLTNATEYGTVYSAHELRALIAPVKAKGYGVHLDGARLAN
HHHCCCCCCCCCCCCCHHHEEECCCCCCCCEECHHHHHHHHHHHCCCCEEEEECCHHHHH
AAAAGFDLKAIKELGVDILVVGGTKAGMPPTEAIVIFDRALARRFDARLKQAGQLPSKGR
HHHCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCC
FYAAPFIGMLGSGAFLRHAAHANAMARRLAELMPFPVVHPVEANAVFVEMDDAALSRLHA
EEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHH
AGWFAYRFLDGSVRFMCSWATTGESVEQLAVTLRDLA
HHHEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHARYDFASDNTAPAAPEALEALAAANTGFTSGYGTDPVSAKAADLVREMLDADAEVRF
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
VASGTAANAVALAALCRPFEAVLAHEHAHVCTDETGAPGFFGQGLGLIRLPGASGRIDPA
EECCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCHH
ALEQPLSAPDVSYRQPAAALSLTNATEYGTVYSAHELRALIAPVKAKGYGVHLDGARLAN
HHHCCCCCCCCCCCCCHHHEEECCCCCCCCEECHHHHHHHHHHHCCCCEEEEECCHHHHH
AAAAGFDLKAIKELGVDILVVGGTKAGMPPTEAIVIFDRALARRFDARLKQAGQLPSKGR
HHHCCCCHHHHHHCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCC
FYAAPFIGMLGSGAFLRHAAHANAMARRLAELMPFPVVHPVEANAVFVEMDDAALSRLHA
EEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHH
AGWFAYRFLDGSVRFMCSWATTGESVEQLAVTLRDLA
HHHEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]