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The map label for this gene is aroB

Identifier: 197104209

GI number: 197104209

Start: 815116

End: 816228

Strand: Reverse

Name: aroB

Synonym: PHZ_c0743

Alternate gene names: 197104209

Gene position: 816228-815116 (Counterclockwise)

Preceding gene: 197104210

Following gene: 197104208

Centisome position: 20.42

GC content: 73.5

Gene sequence:

>1113_bases
ATGACGCGCAGCATCGCCGTCGGCCTGGGCGAGCGCGCCTATGAGGTGCGCGTGGGCGAGAACCTGCTGGACGAGGCCGG
CCGGCACCTGCGGCCCTTCCTCAAGCGCGGCCGCACGGCCGTGGTCAGCGACGAGACGGTCTGGCGCCTGCACGGGGCGC
GGCTGGAGGCGGCCCTCAAGACCGCCGGGGTCGAGGTTCATCCCGTGCTCGTGCCGCCGGGCGAACAGAGCAAGAGCTTC
GCGGGACTGGCCGACGTCACCGACCGCCTGCTGGGCCTGGAGCTCGACCGGGGGGACCTCGTGACCGCGTTCGGCGGCGG
CGTCGTAGGCGACCTCGCCGGCTTCGCCGCGGCGATCTACAAGCGCGGCATCGACTTCATCCAGATCCCCACGACCCTCC
TGGCGCAGGTGGATTCGTCCGTGGGCGGCAAGACGGCGATCGACACCCCCCGCGGCAAGAACCTGGTGGGCGCCTTCCAC
CAGCCGCGGCTGGTGCTGGCCGACCTGTCGGTGCTGGACACCCTGCCGGTCCGCGAGATGCGCGCGGGCTACGCCGAGGT
CATCAAGTACGGCCTGCTGGGCGACCGCGGCTTCTTCGAGTGGCTGGAGGCGAACGGCGCCAAGGTCCTGGCGCGTGAGC
CCGAGGCGCTGACCCACGCCGTCGCGCGTTCCGTGGAGATGAAGGCCGAGATCGTCGCCGAGGACGAACGCGAGCAGGGC
CGCCGGGCGCTGCTCAACCTCGGCCACACCTTCGCCCACGCCCTGGAGGCCGAAACCGGCTACGGTGAGGCCCTGCTGCA
CGGCGAGGCGGTGGGCGTGGGCCAGGCCCTGGCCTTCCGCTTCTCGGCCGCGCTCGACCTGTGCGCCGGCCAGGACGCCG
AGCGCGCGACCCGCGCGATCGCCGCGGCCGGCCTGCCCGTCCGGCTGTCGGAGACGCCCGGCCATCCGTTCGACGCCGAC
CGGCTTGTCGCCCACATGGCCCAGGACAAGAAGGCCGAGGCCGGACGGCTGACGTTCATCCTGGCGCGGGGCCTCGGCAG
CGCCTTCACCGCCAAGGACGTGGAGGCGCAGGCCGTGCGCCGCTTCCTGGTCGCGGAGGGAGCCCGGCCGTGA

Upstream 100 bases:

>100_bases
CCGAGGCGGACATGACGGTCGAAACGGGGGACGTGGCGCACCACGTCACCGTCGACCAGGTGATCCGCGCGCTGTCGGCC
TATCTGGAGGAGCGCGCGGA

Downstream 100 bases:

>100_bases
TCGGCGCGATCATCGTCGCCCTGGCCCCTTCCCTGGTCGTCCTGCTGCTGCTCTCGGCCCTGATGTCGGCGACCGAGACG
TCGATGACCGCGGCGAGCCG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTRSIAVGLGERAYEVRVGENLLDEAGRHLRPFLKRGRTAVVSDETVWRLHGARLEAALKTAGVEVHPVLVPPGEQSKSF
AGLADVTDRLLGLELDRGDLVTAFGGGVVGDLAGFAAAIYKRGIDFIQIPTTLLAQVDSSVGGKTAIDTPRGKNLVGAFH
QPRLVLADLSVLDTLPVREMRAGYAEVIKYGLLGDRGFFEWLEANGAKVLAREPEALTHAVARSVEMKAEIVAEDEREQG
RRALLNLGHTFAHALEAETGYGEALLHGEAVGVGQALAFRFSAALDLCAGQDAERATRAIAAAGLPVRLSETPGHPFDAD
RLVAHMAQDKKAEAGRLTFILARGLGSAFTAKDVEAQAVRRFLVAEGARP

Sequences:

>Translated_370_residues
MTRSIAVGLGERAYEVRVGENLLDEAGRHLRPFLKRGRTAVVSDETVWRLHGARLEAALKTAGVEVHPVLVPPGEQSKSF
AGLADVTDRLLGLELDRGDLVTAFGGGVVGDLAGFAAAIYKRGIDFIQIPTTLLAQVDSSVGGKTAIDTPRGKNLVGAFH
QPRLVLADLSVLDTLPVREMRAGYAEVIKYGLLGDRGFFEWLEANGAKVLAREPEALTHAVARSVEMKAEIVAEDEREQG
RRALLNLGHTFAHALEAETGYGEALLHGEAVGVGQALAFRFSAALDLCAGQDAERATRAIAAAGLPVRLSETPGHPFDAD
RLVAHMAQDKKAEAGRLTFILARGLGSAFTAKDVEAQAVRRFLVAEGARP
>Mature_369_residues
TRSIAVGLGERAYEVRVGENLLDEAGRHLRPFLKRGRTAVVSDETVWRLHGARLEAALKTAGVEVHPVLVPPGEQSKSFA
GLADVTDRLLGLELDRGDLVTAFGGGVVGDLAGFAAAIYKRGIDFIQIPTTLLAQVDSSVGGKTAIDTPRGKNLVGAFHQ
PRLVLADLSVLDTLPVREMRAGYAEVIKYGLLGDRGFFEWLEANGAKVLAREPEALTHAVARSVEMKAEIVAEDEREQGR
RALLNLGHTFAHALEAETGYGEALLHGEAVGVGQALAFRFSAALDLCAGQDAERATRAIAAAGLPVRLSETPGHPFDADR
LVAHMAQDKKAEAGRLTFILARGLGSAFTAKDVEAQAVRRFLVAEGARP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=344, Percent_Identity=47.093023255814, Blast_Score=279, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6320332, Length=332, Percent_Identity=36.7469879518072, Blast_Score=184, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_PHEZH (B4RG33)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002129586.1
- GeneID:   6790236
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c0743
- HOGENOM:   HBG632303
- OMA:   GWIDESI
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39446; Mature: 39315

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSIAVGLGERAYEVRVGENLLDEAGRHLRPFLKRGRTAVVSDETVWRLHGARLEAALK
CCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHH
TAGVEVHPVLVPPGEQSKSFAGLADVTDRLLGLELDRGDLVTAFGGGVVGDLAGFAAAIY
HCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCEECCCCCEEEECCCCHHHHHHHHHHHHH
KRGIDFIQIPTTLLAQVDSSVGGKTAIDTPRGKNLVGAFHQPRLVLADLSVLDTLPVREM
HCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCCHHHH
RAGYAEVIKYGLLGDRGFFEWLEANGAKVLAREPEALTHAVARSVEMKAEIVAEDEREQG
HCCHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHH
RRALLNLGHTFAHALEAETGYGEALLHGEAVGVGQALAFRFSAALDLCAGQDAERATRAI
HHHHHHHHHHHHHHHHCCCCCCHHEECCCHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAAGLPVRLSETPGHPFDADRLVAHMAQDKKAEAGRLTFILARGLGSAFTAKDVEAQAVR
HHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
RFLVAEGARP
HHHHHCCCCC
>Mature Secondary Structure 
TRSIAVGLGERAYEVRVGENLLDEAGRHLRPFLKRGRTAVVSDETVWRLHGARLEAALK
CCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHH
TAGVEVHPVLVPPGEQSKSFAGLADVTDRLLGLELDRGDLVTAFGGGVVGDLAGFAAAIY
HCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCEECCCCCEEEECCCCHHHHHHHHHHHHH
KRGIDFIQIPTTLLAQVDSSVGGKTAIDTPRGKNLVGAFHQPRLVLADLSVLDTLPVREM
HCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCCHHHH
RAGYAEVIKYGLLGDRGFFEWLEANGAKVLAREPEALTHAVARSVEMKAEIVAEDEREQG
HCCHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHH
RRALLNLGHTFAHALEAETGYGEALLHGEAVGVGQALAFRFSAALDLCAGQDAERATRAI
HHHHHHHHHHHHHHHHCCCCCCHHEECCCHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAAGLPVRLSETPGHPFDADRLVAHMAQDKKAEAGRLTFILARGLGSAFTAKDVEAQAVR
HHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
RFLVAEGARP
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA