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The map label for this gene is gdhB [H]

Identifier: 197104077

GI number: 197104077

Start: 654723

End: 655967

Strand: Reverse

Name: gdhB [H]

Synonym: PHZ_c0611

Alternate gene names: 197104077

Gene position: 655967-654723 (Counterclockwise)

Preceding gene: 197104078

Following gene: 197104074

Centisome position: 16.41

GC content: 73.49

Gene sequence:

>1245_bases
ATGAAGACGCTGATGATGGCCGCGGCCGCGGCCGCCCTGCTGGCCGCGTGCGGCGGCGCCGACGGCCAGGCCCAGCCGGC
GACGAAGGCCGGCGGCGACGCGCCCGTCGAGACCAAGGCCGCCAACGCGCCGGACCAGCAGCCGGCCTTCGCCGGCCAGA
CCCGCGCGCCCGAGGTGAAGGCCAATGTCGCCTACGAGGTCAGCGACTACGTCACCGGCCTGCAGAAGCCCTGGGGCCTC
GCCTTCCTGCCGGACGGCGCCCTGCTGGTCAGCGAGAAGGCGGGCCGCCTGCGCCTGTTCGCCGACGGGCGGCTGTCCGA
TCCGCTGGCGGGGGTCCCGCAGGTGGACGCGAACGGCCAGGGGGGCCTCCTGGGCCTGGCCGTCGATCCGGACTTCGCCC
GCAACGGCCTCGTCTACATGGCCTTCTCCGAGCGCCAGGCCGACGGCCGCAACAACACCGCCGTCGCCCGCGGCCGGCTC
GTGACCGCCGCCGGCCAGCCGCCCCGCCTCGAAGGGACCGAGGTGATCTGGCGGCAGACCCCGTCCATCGCCTCGCGCGG
CCACTTCGGCTCGCGCCTGGTGTTCGCCCGCGACGGGACGCTCTACGTCACCACCGGCGACCGGCAGATCAACGAGAGCC
GCCCGAACGCCCAGCGCCTCGACACCACCATCGGCAAGGTCGTGCGGATCAACGCCGACGGCTCGGTCCCGAAGGACAAT
CCCTTCGTCGGCCGCGAGGGCGTGCGGCCCGAGATCTACTCCTCGGGCCACCGCAACATCCAGGCCGCCGCCCTCCACCC
GCAGACCGGCGAGCTGTGGGAGGTCGAGCACGGCACCCGCGGCGGCGACGAGTTGAACATCGTCCGCCCCGGCAAGAACT
ACGGCTGGCCCGACGTGGCCTACGGCATCGAGTACGGCGGCGGGGCCATCACCGGCGGGATCACCCGCAAGGAGGGGATC
GAGCAGCCGATCTACTACTGGGATCCGGTGATCGCCCCCTCGGGCATGGCCTTCTACACCCACGACGCCGCGCCGGCCTG
GAAGGGCAGCCTGTTCGTCGGCGGCCTCGGGCCCAAGTACCTGGCCCGCCTCACCCTCGACGGCGACCGCGTGGTCGGCG
AGGAGCGCCTGCTGACCGAGGTGGGCGAGCGCCTCCGCGACGTCGTCGTCGGCCCCGACGGCGCCCTCTACGTCGCCACC
GACAACGAGGACGGCCGGGTCCTGAAGGTCACGCCTAAGCGGTAG

Upstream 100 bases:

>100_bases
CGCTGCTGTTTTTCGCCGTCTGGGCCCTGATCCACCTGGACGGCGCGCAACCCGAGGATGCGCTGACGAGTCTCGTCGGC
GAGCTATGAGGAGGGACCGG

Downstream 100 bases:

>100_bases
AGCCGGAGGGGGCGGCCGAGAGCCCCAGCCTCGCCGCGGCCTCCTCGCCGATCGCCAGCGAGGAGGTCAGGCCCGGGCTC
TCGATGCCGAACAGGGTCAC

Product: putative glucose dehydrogenase-B, periplasmic protein

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKTLMMAAAAAALLAACGGADGQAQPATKAGGDAPVETKAANAPDQQPAFAGQTRAPEVKANVAYEVSDYVTGLQKPWGL
AFLPDGALLVSEKAGRLRLFADGRLSDPLAGVPQVDANGQGGLLGLAVDPDFARNGLVYMAFSERQADGRNNTAVARGRL
VTAAGQPPRLEGTEVIWRQTPSIASRGHFGSRLVFARDGTLYVTTGDRQINESRPNAQRLDTTIGKVVRINADGSVPKDN
PFVGREGVRPEIYSSGHRNIQAAALHPQTGELWEVEHGTRGGDELNIVRPGKNYGWPDVAYGIEYGGGAITGGITRKEGI
EQPIYYWDPVIAPSGMAFYTHDAAPAWKGSLFVGGLGPKYLARLTLDGDRVVGEERLLTEVGERLRDVVVGPDGALYVAT
DNEDGRVLKVTPKR

Sequences:

>Translated_414_residues
MKTLMMAAAAAALLAACGGADGQAQPATKAGGDAPVETKAANAPDQQPAFAGQTRAPEVKANVAYEVSDYVTGLQKPWGL
AFLPDGALLVSEKAGRLRLFADGRLSDPLAGVPQVDANGQGGLLGLAVDPDFARNGLVYMAFSERQADGRNNTAVARGRL
VTAAGQPPRLEGTEVIWRQTPSIASRGHFGSRLVFARDGTLYVTTGDRQINESRPNAQRLDTTIGKVVRINADGSVPKDN
PFVGREGVRPEIYSSGHRNIQAAALHPQTGELWEVEHGTRGGDELNIVRPGKNYGWPDVAYGIEYGGGAITGGITRKEGI
EQPIYYWDPVIAPSGMAFYTHDAAPAWKGSLFVGGLGPKYLARLTLDGDRVVGEERLLTEVGERLRDVVVGPDGALYVAT
DNEDGRVLKVTPKR
>Mature_414_residues
MKTLMMAAAAAALLAACGGADGQAQPATKAGGDAPVETKAANAPDQQPAFAGQTRAPEVKANVAYEVSDYVTGLQKPWGL
AFLPDGALLVSEKAGRLRLFADGRLSDPLAGVPQVDANGQGGLLGLAVDPDFARNGLVYMAFSERQADGRNNTAVARGRL
VTAAGQPPRLEGTEVIWRQTPSIASRGHFGSRLVFARDGTLYVTTGDRQINESRPNAQRLDTTIGKVVRINADGSVPKDN
PFVGREGVRPEIYSSGHRNIQAAALHPQTGELWEVEHGTRGGDELNIVRPGKNYGWPDVAYGIEYGGGAITGGITRKEGI
EQPIYYWDPVIAPSGMAFYTHDAAPAWKGSLFVGGLGPKYLARLTLDGDRVVGEERLLTEVGERLRDVVVGPDGALYVAT
DNEDGRVLKVTPKR

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI124248546, Length=339, Percent_Identity=26.2536873156342, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI187936955, Length=267, Percent_Identity=26.9662921348315, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI187936953, Length=267, Percent_Identity=26.9662921348315, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI20143973, Length=340, Percent_Identity=22.9411764705882, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787060, Length=345, Percent_Identity=45.2173913043478, Blast_Score=291, Evalue=4e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 43949; Mature: 43949

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLMMAAAAAALLAACGGADGQAQPATKAGGDAPVETKAANAPDQQPAFAGQTRAPEVK
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
ANVAYEVSDYVTGLQKPWGLAFLPDGALLVSEKAGRLRLFADGRLSDPLAGVPQVDANGQ
EEEEEEHHHHHHHCCCCCCEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCC
GGLLGLAVDPDFARNGLVYMAFSERQADGRNNTAVARGRLVTAAGQPPRLEGTEVIWRQT
CCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCCEEEEECC
PSIASRGHFGSRLVFARDGTLYVTTGDRQINESRPNAQRLDTTIGKVVRINADGSVPKDN
CCHHCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCC
PFVGREGVRPEIYSSGHRNIQAAALHPQTGELWEVEHGTRGGDELNIVRPGKNYGWPDVA
CCCCCCCCCCHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCE
YGIEYGGGAITGGITRKEGIEQPIYYWDPVIAPSGMAFYTHDAAPAWKGSLFVGGLGPKY
EEEECCCCEEECCCCHHHCCCCCCEEECCEECCCCCEEEECCCCCCCCCCEEECCCCHHH
LARLTLDGDRVVGEERLLTEVGERLRDVVVGPDGALYVATDNEDGRVLKVTPKR
EEEEEECCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCEEEEECCCC
>Mature Secondary Structure
MKTLMMAAAAAALLAACGGADGQAQPATKAGGDAPVETKAANAPDQQPAFAGQTRAPEVK
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
ANVAYEVSDYVTGLQKPWGLAFLPDGALLVSEKAGRLRLFADGRLSDPLAGVPQVDANGQ
EEEEEEHHHHHHHCCCCCCEEECCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCC
GGLLGLAVDPDFARNGLVYMAFSERQADGRNNTAVARGRLVTAAGQPPRLEGTEVIWRQT
CCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCCEEEEECC
PSIASRGHFGSRLVFARDGTLYVTTGDRQINESRPNAQRLDTTIGKVVRINADGSVPKDN
CCHHCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCC
PFVGREGVRPEIYSSGHRNIQAAALHPQTGELWEVEHGTRGGDELNIVRPGKNYGWPDVA
CCCCCCCCCCHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCE
YGIEYGGGAITGGITRKEGIEQPIYYWDPVIAPSGMAFYTHDAAPAWKGSLFVGGLGPKY
EEEECCCCEEECCCCHHHCCCCCCEEECCEECCCCCEEEECCCCCCCCCCEEECCCCHHH
LARLTLDGDRVVGEERLLTEVGERLRDVVVGPDGALYVATDNEDGRVLKVTPKR
EEEEEECCCCCCCHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]