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The map label for this gene is pgsA [H]

Identifier: 197104066

GI number: 197104066

Start: 641634

End: 642251

Strand: Direct

Name: pgsA [H]

Synonym: PHZ_c0600

Alternate gene names: 197104066

Gene position: 641634-642251 (Clockwise)

Preceding gene: 197104065

Following gene: 197104071

Centisome position: 16.06

GC content: 69.9

Gene sequence:

>618_bases
ATGAAAGCTCTGCCGAACATCCTGACGTCGATGCGCCTGGTGCTGGCGCTGTTCATGTTCGTGGCGCTAGCCGCCGCGGC
GGGGGCGGTGCCCTATCTGTCCGAGCGGCTCACGCCGCTGCAGCAGTTCAGCCTGCAGAGGTGGGCCGTCTACGCGTTCA
TCGTGGCGGCGGTGACCGACTTCTTCGACGGCTGGCTGGCGCGGCGGATGAACGCCGTCAGCGTCTGGGGCGCGATCCTC
GATCCGATCGGCGACAAGGTGCTGGTCTGCGGCGCGATCCTGGGGCTGCTCTCGCTGGGCCCGCAGCCGATGGTCGTCCT
GCCGGCCGGCCTGATCCTGTTCCGCGAGTTCACGGTCAGCGCGCTGCGCGAGGTGGGCGCCGGCCGCGGCGTGAAGCTGC
CGGTCACCCTGCTCGCCAAGTGGAAGACGACGCTGCAGCTCACGGCGCTGGCCATGGAGCTGATCGTCGCCGCCTGGGGC
GCCTTCTCCCTGCCCGAGGAGACCGCGGTCCGCAGCGGGTTCGCGCTGGCGGCTCACGGCCTCTTCTGGATCGCGGCGAT
CGTGACGCTGATCACCGGGGCGCAGTACTGGGAACAGACCCGGAAGGCGCTGAGCTGA

Upstream 100 bases:

>100_bases
AGGGCCTGATCCATAGGGCCTGATCCATGGGGCCTGACGCGCAGGCCGGGGAACAGCTAAGCTCGGGAACGAACCGCCGG
ACCGGACGCTCGATTCCCTC

Downstream 100 bases:

>100_bases
GGGGCGGCTAGGCCTGGGCCTTCAGCGCCCGTTCGCGCTGGGCCTCGCGCCAGCCCTTCTCCTGCTCCATGACCTCGTCG
GAGACGAGGCCCTCGAACGC

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKALPNILTSMRLVLALFMFVALAAAAGAVPYLSERLTPLQQFSLQRWAVYAFIVAAVTDFFDGWLARRMNAVSVWGAIL
DPIGDKVLVCGAILGLLSLGPQPMVVLPAGLILFREFTVSALREVGAGRGVKLPVTLLAKWKTTLQLTALAMELIVAAWG
AFSLPEETAVRSGFALAAHGLFWIAAIVTLITGAQYWEQTRKALS

Sequences:

>Translated_205_residues
MKALPNILTSMRLVLALFMFVALAAAAGAVPYLSERLTPLQQFSLQRWAVYAFIVAAVTDFFDGWLARRMNAVSVWGAIL
DPIGDKVLVCGAILGLLSLGPQPMVVLPAGLILFREFTVSALREVGAGRGVKLPVTLLAKWKTTLQLTALAMELIVAAWG
AFSLPEETAVRSGFALAAHGLFWIAAIVTLITGAQYWEQTRKALS
>Mature_205_residues
MKALPNILTSMRLVLALFMFVALAAAAGAVPYLSERLTPLQQFSLQRWAVYAFIVAAVTDFFDGWLARRMNAVSVWGAIL
DPIGDKVLVCGAILGLLSLGPQPMVVLPAGLILFREFTVSALREVGAGRGVKLPVTLLAKWKTTLQLTALAMELIVAAWG
AFSLPEETAVRSGFALAAHGLFWIAAIVTLITGAQYWEQTRKALS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=203, Percent_Identity=36.4532019704434, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22100; Mature: 22100

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALPNILTSMRLVLALFMFVALAAAAGAVPYLSERLTPLQQFSLQRWAVYAFIVAAVTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FFDGWLARRMNAVSVWGAILDPIGDKVLVCGAILGLLSLGPQPMVVLPAGLILFREFTVS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
ALREVGAGRGVKLPVTLLAKWKTTLQLTALAMELIVAAWGAFSLPEETAVRSGFALAAHG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LFWIAAIVTLITGAQYWEQTRKALS
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKALPNILTSMRLVLALFMFVALAAAAGAVPYLSERLTPLQQFSLQRWAVYAFIVAAVTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FFDGWLARRMNAVSVWGAILDPIGDKVLVCGAILGLLSLGPQPMVVLPAGLILFREFTVS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
ALREVGAGRGVKLPVTLLAKWKTTLQLTALAMELIVAAWGAFSLPEETAVRSGFALAAHG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LFWIAAIVTLITGAQYWEQTRKALS
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8576035 [H]