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The map label for this gene is atpB [H]

Identifier: 197104050

GI number: 197104050

Start: 620064

End: 620849

Strand: Direct

Name: atpB [H]

Synonym: PHZ_c0584

Alternate gene names: 197104050

Gene position: 620064-620849 (Clockwise)

Preceding gene: 197104049

Following gene: 197104051

Centisome position: 15.52

GC content: 66.54

Gene sequence:

>786_bases
ATGGCCGACCCGATGCACCAGTTCGAGGTCCAGAAGATCGTGGACCTCCCGGATCTGACCATCCCCGGCGTGGGCGTCAT
CGATATGGCGTTCACCAACTCGACGCTGGCCATGACCCTGGCCGCCGCCGGGATCGCCACGTTCTTCGGCCTGGCCACGG
CGCGCGGCGCAGTGGTTCCCGGCCGTCTGCAGATGATCGGCGAGGCGGCCTTCGGCTACATCGACGACCTGACGACCAGC
ATCATCGGCCACGAAGGCAAGCGGTTCTTCCCGTTCGTCTTCACGCTCTTCCTGTTCATCCTGGCGATGAACCTGCTGGG
CATGTTCCTGGTGTTCACGGCGACGTCGCAGCTCGCCGTCACCGCGACGCTCGCGGCCCTGACGATCCTCCTGGTGCTGA
TCGTCGGCTTCGCCCGCAACGGCCACAACATGTACAAGCTGTTCGTCCCCTCGGGCGTGCCCTGGTACATGCTGATCCTG
GTGACCCCGATCGAGCTGATCTCGTTCCTGCTCCGGCCGGTCACCCTGGCGCTTCGTCTCTTCGGCAACATGCTCGGCGG
CCACGTGGCCCTGAAGGTGTTCGCCGGTTTCGTGGTCTCGCTGGGCGCGCTGGCGGCCGGCGGCGGCCTCGGGCTGCTGG
GCATCCCCGGCGCCCTGCTGTCGCTGGGCGGCGTCGTCGCCCTGACGGCCCTGGAGTTCCTGGTGGCGTTCCTCCAGGCC
TTCGTCTTCGCAGTTCTGGCCTGCGTCTATCTCAACGACGTGGTCAACCTCGGCCATCACCACTGA

Upstream 100 bases:

>100_bases
TCAGCGCAGCGGATGTCCGCCGAAGCGGAGAGGGAATGGGGTCCCGCGAAGGACCTCCCCCTCGACGGCGACGAGGAAGA
TTGAGGGAGTTCGAGGCGGC

Downstream 100 bases:

>100_bases
TCGGCCGGCAGTACGAACCTTCAACTCTCAACTTCGGTAGGACTAGGACATCATGGAAGCGGAAGCCGCTAAGTACATCG
GCGCTGGTCTCGCGACCCTC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MADPMHQFEVQKIVDLPDLTIPGVGVIDMAFTNSTLAMTLAAAGIATFFGLATARGAVVPGRLQMIGEAAFGYIDDLTTS
IIGHEGKRFFPFVFTLFLFILAMNLLGMFLVFTATSQLAVTATLAALTILLVLIVGFARNGHNMYKLFVPSGVPWYMLIL
VTPIELISFLLRPVTLALRLFGNMLGGHVALKVFAGFVVSLGALAAGGGLGLLGIPGALLSLGGVVALTALEFLVAFLQA
FVFAVLACVYLNDVVNLGHHH

Sequences:

>Translated_261_residues
MADPMHQFEVQKIVDLPDLTIPGVGVIDMAFTNSTLAMTLAAAGIATFFGLATARGAVVPGRLQMIGEAAFGYIDDLTTS
IIGHEGKRFFPFVFTLFLFILAMNLLGMFLVFTATSQLAVTATLAALTILLVLIVGFARNGHNMYKLFVPSGVPWYMLIL
VTPIELISFLLRPVTLALRLFGNMLGGHVALKVFAGFVVSLGALAAGGGLGLLGIPGALLSLGGVVALTALEFLVAFLQA
FVFAVLACVYLNDVVNLGHHH
>Mature_260_residues
ADPMHQFEVQKIVDLPDLTIPGVGVIDMAFTNSTLAMTLAAAGIATFFGLATARGAVVPGRLQMIGEAAFGYIDDLTTSI
IGHEGKRFFPFVFTLFLFILAMNLLGMFLVFTATSQLAVTATLAALTILLVLIVGFARNGHNMYKLFVPSGVPWYMLILV
TPIELISFLLRPVTLALRLFGNMLGGHVALKVFAGFVVSLGALAAGGGLGLLGIPGALLSLGGVVALTALEFLVAFLQAF
VFAVLACVYLNDVVNLGHHH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Homo sapiens, GI251831112, Length=170, Percent_Identity=30.5882352941176, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6226527, Length=264, Percent_Identity=28.4090909090909, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 27596; Mature: 27464

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADPMHQFEVQKIVDLPDLTIPGVGVIDMAFTNSTLAMTLAAAGIATFFGLATARGAVVP
CCCHHHHHHHHHHCCCCCCCCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GRLQMIGEAAFGYIDDLTTSIIGHEGKRFFPFVFTLFLFILAMNLLGMFLVFTATSQLAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATLAALTILLVLIVGFARNGHNMYKLFVPSGVPWYMLILVTPIELISFLLRPVTLALRL
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGNMLGGHVALKVFAGFVVSLGALAAGGGLGLLGIPGALLSLGGVVALTALEFLVAFLQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FVFAVLACVYLNDVVNLGHHH
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA