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The map label for this gene is ywlC [H]

Identifier: 197104025

GI number: 197104025

Start: 592138

End: 593061

Strand: Direct

Name: ywlC [H]

Synonym: PHZ_c0559

Alternate gene names: 197104025

Gene position: 592138-593061 (Clockwise)

Preceding gene: 197104022

Following gene: 197104026

Centisome position: 14.82

GC content: 77.49

Gene sequence:

>924_bases
GTGGACCCGACCGATCCCCATACGGCGGCGCAGGCGCTGAAGGCCGGCGGCCTCGTGCTGATGCCGACCGAGACGGTCTA
CGGACTGGCCGCCGACGCGGCGAACCCGCGCGCCGTCGCCGCCGTCTATGAGGCGAAGGGCCGGCCGAGCTTCAATCCCC
TGATCTCGCATGTGGCGGACGTCGGCATGGCCCGCCGCATCGCGCGGTTCGACCCGCGGGCCGAGGCCCTGACGGCCCGG
TTCTGGCCGGGGCCCCTGACCCTGGTGCTGCCGGCCGCGGACACGGCCGCGGTCTGCGACCTGGCCCGGGCCGGCCTCGA
CACGGTGGCCGTCCGCGCGCCCGCCCATCCGCTGGCCCGGGCCCTGCTGCAGGCGTTCGGCGGCCCGGTGGTGGCGCCGT
CCGCCAACCGCTCGGGCCGCCCCAGCCCCACGACCTTTGCGGCGGCGCTGGAGGAGACCGGCTACGCCGCGGCGGCGGCG
CTCGACGGCGGCCCCTGCGAGGTGGGGCTCGAATCGACCGTCGTCGCCTTGCTGGACGAAGCCCGCCTGCTCAGGCCGGG
GGCGGTGACCCGCGCCGAGATCGAGGCGGTGATCGGGCCGCTGGCCGAGGCGGAGGCGGACGCCAGGCGCTCTCCCGGCC
GGCTGGCGCGCCACTACGCGCCCGACCTGCCCGTGCGGCTGGACGCGGCGGCGCCCGCGGCCGGCGAGGCCTTCCTGGCG
TTCGGCCCGGCGCCCGAGACGGCGCGGACGTTCAACCTCAGCCCGTCCGGCGACCTGAAGGAGGCTGCGGCCAACCTCTT
CGCCATGCTGCGGGCGGCGGACCGCTCGGGAGCGTCGGCCATCGCCGTCGCGCCGATCCCGCACGAGGGCCTGGGCGAGG
CCATCAACGACCGGCTGAAGCGCGCGGCCGGGTTCGTGGGCTGA

Upstream 100 bases:

>100_bases
GTCGCGGACGGGGGCTCGGAAGGTCATGGCCGGGGTTCTAGACGCACGGCGCGAGCCGGGAAAGTTGCCGCATGGGTCAC
CCCTCGTGTAACGGCCGCGG

Downstream 100 bases:

>100_bases
TATAGTCGCCGCATGACCGCTCCCGTCCCCGCCGACGTGATCTCGCGCCTCAAGGCCGTGCTCGGCGAGGGCGGCTGGAG
CGAGGATCCCCAGCGCATCG

Product: Sua5/YciO/YrdC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDPTDPHTAAQALKAGGLVLMPTETVYGLAADAANPRAVAAVYEAKGRPSFNPLISHVADVGMARRIARFDPRAEALTAR
FWPGPLTLVLPAADTAAVCDLARAGLDTVAVRAPAHPLARALLQAFGGPVVAPSANRSGRPSPTTFAAALEETGYAAAAA
LDGGPCEVGLESTVVALLDEARLLRPGAVTRAEIEAVIGPLAEAEADARRSPGRLARHYAPDLPVRLDAAAPAAGEAFLA
FGPAPETARTFNLSPSGDLKEAAANLFAMLRAADRSGASAIAVAPIPHEGLGEAINDRLKRAAGFVG

Sequences:

>Translated_307_residues
MDPTDPHTAAQALKAGGLVLMPTETVYGLAADAANPRAVAAVYEAKGRPSFNPLISHVADVGMARRIARFDPRAEALTAR
FWPGPLTLVLPAADTAAVCDLARAGLDTVAVRAPAHPLARALLQAFGGPVVAPSANRSGRPSPTTFAAALEETGYAAAAA
LDGGPCEVGLESTVVALLDEARLLRPGAVTRAEIEAVIGPLAEAEADARRSPGRLARHYAPDLPVRLDAAAPAAGEAFLA
FGPAPETARTFNLSPSGDLKEAAANLFAMLRAADRSGASAIAVAPIPHEGLGEAINDRLKRAAGFVG
>Mature_307_residues
MDPTDPHTAAQALKAGGLVLMPTETVYGLAADAANPRAVAAVYEAKGRPSFNPLISHVADVGMARRIARFDPRAEALTAR
FWPGPLTLVLPAADTAAVCDLARAGLDTVAVRAPAHPLARALLQAFGGPVVAPSANRSGRPSPTTFAAALEETGYAAAAA
LDGGPCEVGLESTVVALLDEARLLRPGAVTRAEIEAVIGPLAEAEADARRSPGRLARHYAPDLPVRLDAAAPAAGEAFLA
FGPAPETARTFNLSPSGDLKEAAANLFAMLRAADRSGASAIAVAPIPHEGLGEAINDRLKRAAGFVG

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=143, Percent_Identity=34.2657342657343, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=378, Percent_Identity=33.5978835978836, Blast_Score=155, Evalue=6e-39,
Organism=Drosophila melanogaster, GI78707274, Length=173, Percent_Identity=31.7919075144509, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 31345; Mature: 31345

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPTDPHTAAQALKAGGLVLMPTETVYGLAADAANPRAVAAVYEAKGRPSFNPLISHVAD
CCCCCHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCHHEEEEECCCCCCCHHHHHHHHHH
VGMARRIARFDPRAEALTARFWPGPLTLVLPAADTAAVCDLARAGLDTVAVRAPAHPLAR
HHHHHHHHHCCCHHHHHEEEECCCCEEEEEECCCHHHHHHHHHCCCCCEEEECCCHHHHH
ALLQAFGGPVVAPSANRSGRPSPTTFAAALEETGYAAAAALDGGPCEVGLESTVVALLDE
HHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHH
ARLLRPGAVTRAEIEAVIGPLAEAEADARRSPGRLARHYAPDLPVRLDAAAPAAGEAFLA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCCCCEEEE
FGPAPETARTFNLSPSGDLKEAAANLFAMLRAADRSGASAIAVAPIPHEGLGEAINDRLK
ECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHH
RAAGFVG
HHHCCCC
>Mature Secondary Structure
MDPTDPHTAAQALKAGGLVLMPTETVYGLAADAANPRAVAAVYEAKGRPSFNPLISHVAD
CCCCCHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCHHEEEEECCCCCCCHHHHHHHHHH
VGMARRIARFDPRAEALTARFWPGPLTLVLPAADTAAVCDLARAGLDTVAVRAPAHPLAR
HHHHHHHHHCCCHHHHHEEEECCCCEEEEEECCCHHHHHHHHHCCCCCEEEECCCHHHHH
ALLQAFGGPVVAPSANRSGRPSPTTFAAALEETGYAAAAALDGGPCEVGLESTVVALLDE
HHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHH
ARLLRPGAVTRAEIEAVIGPLAEAEADARRSPGRLARHYAPDLPVRLDAAAPAAGEAFLA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCCCCEEEE
FGPAPETARTFNLSPSGDLKEAAANLFAMLRAADRSGASAIAVAPIPHEGLGEAINDRLK
ECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHH
RAAGFVG
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]