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The map label for this gene is rfbF [H]

Identifier: 197103960

GI number: 197103960

Start: 519131

End: 519898

Strand: Direct

Name: rfbF [H]

Synonym: PHZ_c0494

Alternate gene names: 197103960

Gene position: 519131-519898 (Clockwise)

Preceding gene: 197103959

Following gene: 197103961

Centisome position: 12.99

GC content: 67.71

Gene sequence:

>768_bases
ATGAAGACGGTGATCCTGGCCGGCGGCCTCGGCACGCGGATTTCGGAAGAAAGCCACCTGAAGCCCAAGCCGATGATCGA
GATCGGCGGCCGGCCCATCCTGTGGCACATCATGAAGCTGTACTCGCACCACGGCTTCAACGACTTCATCGTCTGCCTGG
GCTACAAGGGCTATGTGGTGAAGGAGTACTTCGCCAACTACGTGCTCCATCACGCCGACATCACGGTCGACCTGGACAAG
GGCGCCATCGAGTATCACGCGACCAACCACGAACCCTGGCGGGTGACGCTGGTGGAGACCGGCGCCGAGACCATGACCGG
CGGACGGCTGAAGCGGGTGGCGCGCTATCTCGATCCCGGCGAGCCGTTCTTCTTCACCTACGGCGACGGCCTTGCCGACG
TGGACCTGAAGGCCCTGGCGGCCTTCCACCGCGGGCACGGCAAGGCGGCGACGATCACCGCCGTCGCCCCGCCCGGGCGC
TACGGCGCCCTGGAGATCGAGGCCGGGCAGGTCCAGCGTTTCACCGAGAAGCCCCCGGGCGACAACGGCCTGATCAACGG
CGGCTTCTTCGTCCTGCAGCCCGAGGTGATCTCGCGCATCGCCGGCGACGCCACCACCTGGGAGAACGAGCCGCTGGAGG
GCCTGGCCCGCGACGGGGAACTGATGGCCTACCGCCACGACGGCTTCTGGGCGGCGATGGACACCCTGCGCGACAAGAAC
CACCTGGAGGCGCTCTGGGCTTCGGGCGAGGCGCCGTGGCGCCGGTGA

Upstream 100 bases:

>100_bases
TGGCTTACTAGCCGCCCGCGCGTGGGGCCGCTAAGAGGTCACGACTGCGCCCAGGGACGTGCTTGGGGCGCTACGGGGGC
GGCGCGAAGGGTGCCTTGAG

Downstream 100 bases:

>100_bases
ACCGCGACTTCTGGGCCGGCAAGCGGGTCCTGCTGACCGGCCACACGGGCTTCAAAGGCTCCTGGGCGGCGATCTGGCTG
ACCGCCATGGGCGTCGAGGT

Product: glucose-1-phosphate cytidylyltransferase protein

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKTVILAGGLGTRISEESHLKPKPMIEIGGRPILWHIMKLYSHHGFNDFIVCLGYKGYVVKEYFANYVLHHADITVDLDK
GAIEYHATNHEPWRVTLVETGAETMTGGRLKRVARYLDPGEPFFFTYGDGLADVDLKALAAFHRGHGKAATITAVAPPGR
YGALEIEAGQVQRFTEKPPGDNGLINGGFFVLQPEVISRIAGDATTWENEPLEGLARDGELMAYRHDGFWAAMDTLRDKN
HLEALWASGEAPWRR

Sequences:

>Translated_255_residues
MKTVILAGGLGTRISEESHLKPKPMIEIGGRPILWHIMKLYSHHGFNDFIVCLGYKGYVVKEYFANYVLHHADITVDLDK
GAIEYHATNHEPWRVTLVETGAETMTGGRLKRVARYLDPGEPFFFTYGDGLADVDLKALAAFHRGHGKAATITAVAPPGR
YGALEIEAGQVQRFTEKPPGDNGLINGGFFVLQPEVISRIAGDATTWENEPLEGLARDGELMAYRHDGFWAAMDTLRDKN
HLEALWASGEAPWRR
>Mature_255_residues
MKTVILAGGLGTRISEESHLKPKPMIEIGGRPILWHIMKLYSHHGFNDFIVCLGYKGYVVKEYFANYVLHHADITVDLDK
GAIEYHATNHEPWRVTLVETGAETMTGGRLKRVARYLDPGEPFFFTYGDGLADVDLKALAAFHRGHGKAATITAVAPPGR
YGALEIEAGQVQRFTEKPPGDNGLINGGFFVLQPEVISRIAGDATTWENEPLEGLARDGELMAYRHDGFWAAMDTLRDKN
HLEALWASGEAPWRR

Specific function: Involved in the biosynthesis of the tyvelose, a 3,6- dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucle

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=254, Percent_Identity=29.9212598425197, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI11761619, Length=253, Percent_Identity=30.0395256916996, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI133931050, Length=250, Percent_Identity=28.8, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320148, Length=249, Percent_Identity=30.5220883534137, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI21355443, Length=251, Percent_Identity=29.4820717131474, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24644084, Length=251, Percent_Identity=29.4820717131474, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 28343; Mature: 28343

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVILAGGLGTRISEESHLKPKPMIEIGGRPILWHIMKLYSHHGFNDFIVCLGYKGYVV
CCEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCHH
KEYFANYVLHHADITVDLDKGAIEYHATNHEPWRVTLVETGAETMTGGRLKRVARYLDPG
HHHHHHHHEEECEEEEEECCCEEEEEECCCCCEEEEEEECCCCHHCCHHHHHHHHHCCCC
EPFFFTYGDGLADVDLKALAAFHRGHGKAATITAVAPPGRYGALEIEAGQVQRFTEKPPG
CCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCHHHHHHCCCCC
DNGLINGGFFVLQPEVISRIAGDATTWENEPLEGLARDGELMAYRHDGFWAAMDTLRDKN
CCCEEECCEEEECHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHCCCC
HLEALWASGEAPWRR
HHHHEECCCCCCCCC
>Mature Secondary Structure
MKTVILAGGLGTRISEESHLKPKPMIEIGGRPILWHIMKLYSHHGFNDFIVCLGYKGYVV
CCEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCHH
KEYFANYVLHHADITVDLDKGAIEYHATNHEPWRVTLVETGAETMTGGRLKRVARYLDPG
HHHHHHHHEEECEEEEEECCCEEEEEECCCCCEEEEEEECCCCHHCCHHHHHHHHHCCCC
EPFFFTYGDGLADVDLKALAAFHRGHGKAATITAVAPPGRYGALEIEAGQVQRFTEKPPG
CCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCHHHHHHCCCCC
DNGLINGGFFVLQPEVISRIAGDATTWENEPLEGLARDGELMAYRHDGFWAAMDTLRDKN
CCCEEECCEEEECHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHCCCC
HLEALWASGEAPWRR
HHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]