BacMap

Definition	Phenylobacterium zucineum HLK1, complete genome.
Accession	NC_011144
Length	3,996,255

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The map label for this gene is phbB [H]

Identifier: 197103898

GI number: 197103898

Start: 439871

End: 440596

Strand: Direct

Name: phbB [H]

Synonym: PHZ_c0432

Alternate gene names: 197103898

Gene position: 439871-440596 (Clockwise)

Preceding gene: 197103897

Following gene: 197103899

Centisome position: 11.01

GC content: 69.42

Gene sequence:

>726_bases
ATGGCCCGTGTGGCTCTCGTGACCGGCGGCACGCGCGGCATCGGCCGCGCCATCGTGGAGCGGCTGAAGGCCGACGGGAT
GAAGGTGGCGGCCGGCTATTCCGGCAACGACGAGGCGGCGGCCGCCTGCGCCCGGGACCTCGGCGTGATGGTCGTGAAGG
GCAACGTCGGGGTGTTCGACGACTGCCGGCGAGCCGTCGGGCAGGTCGAGGCCGAGCTGGGCCCGGTGGACGTGCTGGTG
AACAACGCCGGCATCACCCGCGACGGCTTCTTCCACAAGATGACCCCCGAGCAGTGGAGCGAGGTCATCCGCGTCAACAT
GGACTCGCTCTACAACATGACCCGCCAGGTCATCGAGGGGATGCGCGAGCGCGAGTGGGGCCGGATCGTCAACATCAGCT
CGATCAACGGCCAGAAGGGCCAGCTGGGCCAGACCAACTACTCGGCGGCCAAGGCCGGCGTGATCGGCTTCACCAAGGCC
CTGGCGCTGGAGAACGCCCGCAAGGGGGTGACGGTCAACTGCGTGGCCCCCGGTTACGTGGACACCGAGATGGTGCAGGC
GGTGCCGCCCAAGGTGCTGGAGGGAATCATCGCCCAGATCCCGGCGGGCCGGCTCGGCCGGGGCGAGGAGATCGCCGATG
CGGTCTCGTTCCTCGCGGGCGAGCGCGCCGGCTACGTCAACGGGTCGACGCTTTCGCTGAATGGCGGCCAGTACCTCGTC
GGCTGA

Upstream 100 bases:

>100_bases
TGCGTCGGCGGCGGCATGGGCGTGGCCATGTGCGTCGAGACGGTGTGAGCGGGAAAGGCCGGCGCCTGAGGCCGGCCGCC
GCCGACTAGGGAGGTGTGGA

Downstream 100 bases:

>100_bases
GCGCCTCGGGGGCGTCCAAAAAGCGCCCCGATCCCGGAGCATGTGCTGCGGGATCATGACGGGCGAGCCCACGGCGTCCA
GGATTGCGGTTCTCGCGGCG

Product: acetoacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MARVALVTGGTRGIGRAIVERLKADGMKVAAGYSGNDEAAAACARDLGVMVVKGNVGVFDDCRRAVGQVEAELGPVDVLV
NNAGITRDGFFHKMTPEQWSEVIRVNMDSLYNMTRQVIEGMREREWGRIVNISSINGQKGQLGQTNYSAAKAGVIGFTKA
LALENARKGVTVNCVAPGYVDTEMVQAVPPKVLEGIIAQIPAGRLGRGEEIADAVSFLAGERAGYVNGSTLSLNGGQYLV
G

Sequences:

>Translated_241_residues
MARVALVTGGTRGIGRAIVERLKADGMKVAAGYSGNDEAAAACARDLGVMVVKGNVGVFDDCRRAVGQVEAELGPVDVLV
NNAGITRDGFFHKMTPEQWSEVIRVNMDSLYNMTRQVIEGMREREWGRIVNISSINGQKGQLGQTNYSAAKAGVIGFTKA
LALENARKGVTVNCVAPGYVDTEMVQAVPPKVLEGIIAQIPAGRLGRGEEIADAVSFLAGERAGYVNGSTLSLNGGQYLV
G
>Mature_240_residues
ARVALVTGGTRGIGRAIVERLKADGMKVAAGYSGNDEAAAACARDLGVMVVKGNVGVFDDCRRAVGQVEAELGPVDVLVN
NAGITRDGFFHKMTPEQWSEVIRVNMDSLYNMTRQVIEGMREREWGRIVNISSINGQKGQLGQTNYSAAKAGVIGFTKAL
ALENARKGVTVNCVAPGYVDTEMVQAVPPKVLEGIIAQIPAGRLGRGEEIADAVSFLAGERAGYVNGSTLSLNGGQYLVG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=40.4, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=37.603305785124, Blast_Score=141, Evalue=4e-34,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=33.7448559670782, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=32.6359832635983, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4504505, Length=203, Percent_Identity=33.9901477832512, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=32.0833333333333, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI66933014, Length=184, Percent_Identity=32.0652173913043, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4758504, Length=249, Percent_Identity=31.3253012048193, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI59889578, Length=207, Percent_Identity=32.3671497584541, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI126723750, Length=244, Percent_Identity=28.6885245901639, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI109715829, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=29.9595141700405, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=33.5078534031414, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI226371731, Length=210, Percent_Identity=31.4285714285714, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI83715985, Length=250, Percent_Identity=30, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=31.9587628865979, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=32.2222222222222, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=29.4736842105263, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7705855, Length=208, Percent_Identity=30.2884615384615, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=31.7647058823529, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI142976729, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503301, Length=193, Percent_Identity=24.3523316062176, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=31.9371727748691, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=46.0905349794239, Blast_Score=213, Evalue=7e-57,
Organism=Escherichia coli, GI1790717, Length=237, Percent_Identity=32.4894514767932, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=32.1285140562249, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=32.2448979591837, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=32.2448979591837, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=33.4728033472803, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=30.4526748971193, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=29.3388429752066, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=29.7959183673469, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=28.0155642023346, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787905, Length=167, Percent_Identity=29.3413173652695, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787820, Length=242, Percent_Identity=30.1652892561983, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=39.5161290322581, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=41.0041841004184, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=31.6872427983539, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17538182, Length=245, Percent_Identity=31.8367346938775, Blast_Score=106, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=30.4878048780488, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=31.4741035856574, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=32.3886639676113, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17568967, Length=201, Percent_Identity=31.3432835820896, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=31.6981132075472, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=30.9433962264151, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=33.0769230769231, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=31.1538461538462, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=30.4182509505703, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=29.0816326530612, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=29.0816326530612, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=29.6153846153846, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=28.2442748091603, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=30.3846153846154, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=29.6153846153846, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=29.7709923664122, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.6577946768061, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=28.2945736434109, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.4809160305344, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=181, Percent_Identity=27.0718232044199, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.7575757575758, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=29.5019157088123, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=239, Percent_Identity=27.6150627615063, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=26.5151515151515, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=26.953125, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=25.1937984496124, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=28.2051282051282, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193207185, Length=149, Percent_Identity=32.2147651006711, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=24.8062015503876, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=33.9901477832512, Blast_Score=112, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=29.4820717131474, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322795, Length=273, Percent_Identity=27.4725274725275, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=39.4190871369295, Blast_Score=157, Evalue=5e-39,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=34.0248962655602, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=32.7935222672065, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=33.6065573770492, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=36.7875647668394, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=32.9317269076305, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=30.8016877637131, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=30.5084745762712, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=31.1023622047244, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644337, Length=170, Percent_Identity=34.1176470588235, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641232, Length=231, Percent_Identity=30.7359307359307, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656154, Length=209, Percent_Identity=32.0574162679426, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922628, Length=209, Percent_Identity=32.0574162679426, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581726, Length=142, Percent_Identity=29.5774647887324, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=201, Percent_Identity=31.8407960199005, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24649181, Length=187, Percent_Identity=30.4812834224599, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574402, Length=201, Percent_Identity=31.8407960199005, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=28.6549707602339, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641388, Length=232, Percent_Identity=29.3103448275862, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=199, Percent_Identity=30.1507537688442, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=26.1780104712042, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356301, Length=214, Percent_Identity=25.2336448598131, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 25428; Mature: 25297

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVALVTGGTRGIGRAIVERLKADGMKVAAGYSGNDEAAAACARDLGVMVVKGNVGVFD
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCHH
DCRRAVGQVEAELGPVDVLVNNAGITRDGFFHKMTPEQWSEVIRVNMDSLYNMTRQVIEG
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCHHHHHHHHHHCHHHHHHHHHHHHHH
MREREWGRIVNISSINGQKGQLGQTNYSAAKAGVIGFTKALALENARKGVTVNCVAPGYV
HHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DTEMVQAVPPKVLEGIIAQIPAGRLGRGEEIADAVSFLAGERAGYVNGSTLSLNGGQYLV
CHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEC
G
C
>Mature Secondary Structure 
ARVALVTGGTRGIGRAIVERLKADGMKVAAGYSGNDEAAAACARDLGVMVVKGNVGVFD
CEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCHH
DCRRAVGQVEAELGPVDVLVNNAGITRDGFFHKMTPEQWSEVIRVNMDSLYNMTRQVIEG
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCHHHHHHHHHHCHHHHHHHHHHHHHH
MREREWGRIVNISSINGQKGQLGQTNYSAAKAGVIGFTKALALENARKGVTVNCVAPGYV
HHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DTEMVQAVPPKVLEGIIAQIPAGRLGRGEEIADAVSFLAGERAGYVNGSTLSLNGGQYLV
CHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2546004; 3286259 [H]