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The map label for this gene is pheA [H]

Identifier: 197103828

GI number: 197103828

Start: 366731

End: 367591

Strand: Direct

Name: pheA [H]

Synonym: PHZ_c0362

Alternate gene names: 197103828

Gene position: 366731-367591 (Clockwise)

Preceding gene: 197103827

Following gene: 197103831

Centisome position: 9.18

GC content: 68.52

Gene sequence:

>861_bases
ATGAGCCAGGCCGGCAGCGGGGGACGCATCGCCTTCCAGGGCGAGCTCGGGGCCAACAGCCACGAGGCCTGCTCGCAGTT
CTTCCCCGATCACGAGCCGGTCCCCCACGCCAGCTTCGAGGACGCCTTCGAGGCGGTGAAGTCGGGTGACTGCCAGCTGG
GCCTGATCCCGGTGGAGAACTCGATCGCCGGCCGCGTGGCCGACGTCCACCACCTCCTGCCGTCCTCGGGCCTGAAGATC
GTCGGCGAGCGGTTCAAGCCGATCCACTTCCAGCTGATGGTCAATCCGGGCGTGACCCTGGAGCAGGTGACGACGGCGGT
CTCGATGCCGATCGCGCTCGGCCAGTGCCGCAAGACCCTGCGCAAGCTGAAGCTGAAGACCCAGGCCGCCGGCGACACGG
CCGGGGCGGCCAAGGAGCTGGCCGAGAGCCCCGACCCCACCAAGGCGGCGGTGAGCCCGGCCCTCTGCGCCGAGCTCTAT
GGGCTGGAGATCCTGGTCCGCGACATCGAGGACGAGCACAACAACACCACGCGCTTCCTGGTGATGACGGCGCAGAAGGA
CCCGCCGCCGCCGCCGTTCACCCAGCCCTGCGTGACGAGCTTCATCTTCCGGGTGAAGAACCTGCCGGCGGCGCTCTACA
AGGCGCTGGGGGGCTTCGCGACCAACGGCGTCAACATGACCAAGCTCGAGAGCTACATGGAGAACGGCGCGTTCACCGCG
ACCTTCTTCTACGCCGAGGTGGACGGCCGGCCCGAGGACATCGGCGTGGCCCGCGCCTTCGACGAGCTGAGGTTCTTCTC
GGAGAAGTTCGAGATCCTCGGCGTCTATCCGGCCGACCCGTTCCGCACGAGCCGGGGGTAG

Upstream 100 bases:

>100_bases
CCATCTGGGCCACGGTGGCCGACGCCGCGCCCATCTCGGTGGACACGCCGGCCGACCTGGCCGCCGCCCGCCATTTCGTC
AGCACGATCGGGGGACCGCA

Downstream 100 bases:

>100_bases
CGCCGCGCGGCCGCTCCCTCGCCCCGCTTCGCGGGGGGAGAGGAGGGGTCAGCCTTCCTCGACCCAGGCCTTGAGGAGCT
GGTGGGCGATGGCGAGCGGG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSQAGSGGRIAFQGELGANSHEACSQFFPDHEPVPHASFEDAFEAVKSGDCQLGLIPVENSIAGRVADVHHLLPSSGLKI
VGERFKPIHFQLMVNPGVTLEQVTTAVSMPIALGQCRKTLRKLKLKTQAAGDTAGAAKELAESPDPTKAAVSPALCAELY
GLEILVRDIEDEHNNTTRFLVMTAQKDPPPPPFTQPCVTSFIFRVKNLPAALYKALGGFATNGVNMTKLESYMENGAFTA
TFFYAEVDGRPEDIGVARAFDELRFFSEKFEILGVYPADPFRTSRG

Sequences:

>Translated_286_residues
MSQAGSGGRIAFQGELGANSHEACSQFFPDHEPVPHASFEDAFEAVKSGDCQLGLIPVENSIAGRVADVHHLLPSSGLKI
VGERFKPIHFQLMVNPGVTLEQVTTAVSMPIALGQCRKTLRKLKLKTQAAGDTAGAAKELAESPDPTKAAVSPALCAELY
GLEILVRDIEDEHNNTTRFLVMTAQKDPPPPPFTQPCVTSFIFRVKNLPAALYKALGGFATNGVNMTKLESYMENGAFTA
TFFYAEVDGRPEDIGVARAFDELRFFSEKFEILGVYPADPFRTSRG
>Mature_285_residues
SQAGSGGRIAFQGELGANSHEACSQFFPDHEPVPHASFEDAFEAVKSGDCQLGLIPVENSIAGRVADVHHLLPSSGLKIV
GERFKPIHFQLMVNPGVTLEQVTTAVSMPIALGQCRKTLRKLKLKTQAAGDTAGAAKELAESPDPTKAAVSPALCAELYG
LEILVRDIEDEHNNTTRFLVMTAQKDPPPPPFTQPCVTSFIFRVKNLPAALYKALGGFATNGVNMTKLESYMENGAFTAT
FFYAEVDGRPEDIGVARAFDELRFFSEKFEILGVYPADPFRTSRG

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=278, Percent_Identity=29.4964028776978, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30964; Mature: 30832

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAGSGGRIAFQGELGANSHEACSQFFPDHEPVPHASFEDAFEAVKSGDCQLGLIPVEN
CCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
SIAGRVADVHHLLPSSGLKIVGERFKPIHFQLMVNPGVTLEQVTTAVSMPIALGQCRKTL
CHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
RKLKLKTQAAGDTAGAAKELAESPDPTKAAVSPALCAELYGLEILVRDIEDEHNNTTRFL
HHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHEEHHHCCCCCCEEEE
VMTAQKDPPPPPFTQPCVTSFIFRVKNLPAALYKALGGFATNGVNMTKLESYMENGAFTA
EEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCHHCCCCCHHHHHHHHHCCCEEE
TFFYAEVDGRPEDIGVARAFDELRFFSEKFEILGVYPADPFRTSRG
EEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SQAGSGGRIAFQGELGANSHEACSQFFPDHEPVPHASFEDAFEAVKSGDCQLGLIPVEN
CCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
SIAGRVADVHHLLPSSGLKIVGERFKPIHFQLMVNPGVTLEQVTTAVSMPIALGQCRKTL
CHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
RKLKLKTQAAGDTAGAAKELAESPDPTKAAVSPALCAELYGLEILVRDIEDEHNNTTRFL
HHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHEEHHHCCCCCCEEEE
VMTAQKDPPPPPFTQPCVTSFIFRVKNLPAALYKALGGFATNGVNMTKLESYMENGAFTA
EEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCHHCCCCCHHHHHHHHHCCCEEE
TFFYAEVDGRPEDIGVARAFDELRFFSEKFEILGVYPADPFRTSRG
EEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]