Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 197103827

GI number: 197103827

Start: 365976

End: 366734

Strand: Direct

Name: kdsB [H]

Synonym: PHZ_c0361

Alternate gene names: 197103827

Gene position: 365976-366734 (Clockwise)

Preceding gene: 197103825

Following gene: 197103828

Centisome position: 9.16

GC content: 73.65

Gene sequence:

>759_bases
ATGAACCCCATCGTCCTCATCCCGGCGCGACTGGCCGCCACGCGCCTGCCGGGCAAGCCCCTGGCGGACATCGGCGGCGT
ACCGATGATCGTCCGCGTGCTGCGGCAGGCGCAGGCCGCAGGCGCAGGACCGGTGGCGGTGGCGGCGGGCGATCCCGAGA
TCGTGGAGGCCGTGGAGCAGGCGGGCGGGCGCGCGGTGCTGACCGACCCCGAGCTGCCGTCGGGCTCGGACCGGATCCTG
GCGGCCCTGGCCGTCCTCGACCCCGAAGGGCGGCACGACGTGATCGTCAACCTGCAGGGCGACATGCCGTTCGTGGAGCC
GGACGTGATCACCGCCTGCGCCGGGCTGCTGGCCGAGATCCCCGACTGCGACATCGCCACGGTGGTGGCGCCCGAGGCCT
CGCCCGAGGACCGGACGAACCCGGACGTGGTGAAGGCGGTTCTGTCGATGCAGCCGGGCGGCCAGACGGGAGGGCGGACG
GGACGGGCGCTCTACTTCACCCGCTCGACCCTCTACGGCGACCATCCGGTGTGGCGGCACGTGGGCATCTACGGCTACCG
GCGCGAGGCGCTGGAGGCGTTCAACGCCGCCGAGCCGTCGCCCCTGGAGCGCCGCGAGAAGCTGGAGCAGCTGCGGGCGC
TGGAGCTGGGCCTTTCCATCTGGGCCACGGTGGCCGACGCCGCGCCCATCTCGGTGGACACGCCGGCCGACCTGGCCGCC
GCCCGCCATTTCGTCAGCACGATCGGGGGACCGCAATGA

Upstream 100 bases:

>100_bases
GCCGACGCCGCCGTCGGCGAACGACGCGGGAAACCCGCCCCTTGTTGCGTGCGGCTCTCTTACACGGTACCGGCGCTGGC
GCAACCGCCCAGAAGCCCGC

Downstream 100 bases:

>100_bases
GCCAGGCCGGCAGCGGGGGACGCATCGCCTTCCAGGGCGAGCTCGGGGCCAACAGCCACGAGGCCTGCTCGCAGTTCTTC
CCCGATCACGAGCCGGTCCC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNPIVLIPARLAATRLPGKPLADIGGVPMIVRVLRQAQAAGAGPVAVAAGDPEIVEAVEQAGGRAVLTDPELPSGSDRIL
AALAVLDPEGRHDVIVNLQGDMPFVEPDVITACAGLLAEIPDCDIATVVAPEASPEDRTNPDVVKAVLSMQPGGQTGGRT
GRALYFTRSTLYGDHPVWRHVGIYGYRREALEAFNAAEPSPLERREKLEQLRALELGLSIWATVADAAPISVDTPADLAA
ARHFVSTIGGPQ

Sequences:

>Translated_252_residues
MNPIVLIPARLAATRLPGKPLADIGGVPMIVRVLRQAQAAGAGPVAVAAGDPEIVEAVEQAGGRAVLTDPELPSGSDRIL
AALAVLDPEGRHDVIVNLQGDMPFVEPDVITACAGLLAEIPDCDIATVVAPEASPEDRTNPDVVKAVLSMQPGGQTGGRT
GRALYFTRSTLYGDHPVWRHVGIYGYRREALEAFNAAEPSPLERREKLEQLRALELGLSIWATVADAAPISVDTPADLAA
ARHFVSTIGGPQ
>Mature_252_residues
MNPIVLIPARLAATRLPGKPLADIGGVPMIVRVLRQAQAAGAGPVAVAAGDPEIVEAVEQAGGRAVLTDPELPSGSDRIL
AALAVLDPEGRHDVIVNLQGDMPFVEPDVITACAGLLAEIPDCDIATVVAPEASPEDRTNPDVVKAVLSMQPGGQTGGRT
GRALYFTRSTLYGDHPVWRHVGIYGYRREALEAFNAAEPSPLERREKLEQLRALELGLSIWATVADAAPISVDTPADLAA
ARHFVSTIGGPQ

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=255, Percent_Identity=40.3921568627451, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 26419; Mature: 26419

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIVLIPARLAATRLPGKPLADIGGVPMIVRVLRQAQAAGAGPVAVAAGDPEIVEAVEQ
CCCEEEECCHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
AGGRAVLTDPELPSGSDRILAALAVLDPEGRHDVIVNLQGDMPFVEPDVITACAGLLAEI
CCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHC
PDCDIATVVAPEASPEDRTNPDVVKAVLSMQPGGQTGGRTGRALYFTRSTLYGDHPVWRH
CCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHH
VGIYGYRREALEAFNAAEPSPLERREKLEQLRALELGLSIWATVADAAPISVDTPADLAA
HCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ARHFVSTIGGPQ
HHHHHHHCCCCC
>Mature Secondary Structure
MNPIVLIPARLAATRLPGKPLADIGGVPMIVRVLRQAQAAGAGPVAVAAGDPEIVEAVEQ
CCCEEEECCHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
AGGRAVLTDPELPSGSDRILAALAVLDPEGRHDVIVNLQGDMPFVEPDVITACAGLLAEI
CCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHC
PDCDIATVVAPEASPEDRTNPDVVKAVLSMQPGGQTGGRTGRALYFTRSTLYGDHPVWRH
CCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHH
VGIYGYRREALEAFNAAEPSPLERREKLEQLRALELGLSIWATVADAAPISVDTPADLAA
HCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
ARHFVSTIGGPQ
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA