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The map label for this gene is ampR [H]

Identifier: 197103812

GI number: 197103812

Start: 349538

End: 350413

Strand: Direct

Name: ampR [H]

Synonym: PHZ_c0346

Alternate gene names: 197103812

Gene position: 349538-350413 (Clockwise)

Preceding gene: 197103810

Following gene: 197103817

Centisome position: 8.75

GC content: 75.23

Gene sequence:

>876_bases
ATGGTGCGACCCTACCTTCCCCTGAACGGCCTACGCGCCTTCGAGGCGGCGGCGCGGCACCTGTCGTTCACCAAGGCCGC
TATCGAGCTGTGCGTCACCCAGGCGGCGGTCAGCCAGCAGGTGAAGGCGCTGGAGGGGCGGCTGGGGCGGCGACTGTTCC
GCCGACTGCCGCGGGGTCTGGCGCTGACGGACGAGGGCCTGGCCCTGCTGCCGGCGGTGGCCGAGAGCCTGGACCGGCTG
GGCGAGGCGGTGGAACGGGTGGGCCAGGCCCGCCCGCGCGAAGTGGTCAACGTCGGCGTGGTGGCGACCTTCGCCCTGGG
CTTCCTGCTGCCGCGCCTGCCGGCGCTGGCGGCGGCCGCGCCGCAGATCGACCTGCGCCTCTTCACCAACAACAACCGCG
TGGACATGGCCGGAGAGGGCCTGGACTGCGCCATCCGGTTCGGCGACGGCGCCTGGCACGGGACCCACGCCGAGCGGCTG
ATGGACGGGGCGATGACGCCGCTGTGCGCCCCGGGCGTGGCGCGGCGGCTGGAGACGCCCGCGGATCTGTTGGGCGAAAC
CCTGCTGCGCTCGTACCGGGCCGAGGAATGGACCCGCTGGTTCGCCCTGGCGGGCGTGCCGGTCCCGCCGCTGCGGGGGC
CGGTGTTCGACTCCTCGCTGGCCATGGCCGAGGCGGCCGAGCAGGGCCTGGGGGTGGCGCTGGCGCCGGCGGCGATGTTC
CGCGCGCGCATCGACCGCGGGGCGCTGGTGCAGCCGTTCCGGCTGGACGCGCCGGTCGGCGGCTACTGGCTCACCTGGCT
GAGGTCGAAGGCGCCGACCGAGGGGATGCTGGCGTTCCGCGCCTGGCTCTCCGAGGCCTGCGGCGAGGCGCCCTAG

Upstream 100 bases:

>100_bases
GCGGCGCGCCGGGCCGACGGCCGCCCTTTGATGGCGCAGGCGCCGGGCGCAGTGCAAAGGACCTTTCCTGGCGGGAGCCA
TAAGCCTAGGTAATGGCGCG

Downstream 100 bases:

>100_bases
CCGGCGGCCGCGGCGTCCACGGCGGGCGGGCAGGTCTCACGCACGCTGTCCCAGACGGCGAGGACGCCCAGCTGCGACAG
GGACGCCATCAGCCGCTGGA

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MVRPYLPLNGLRAFEAAARHLSFTKAAIELCVTQAAVSQQVKALEGRLGRRLFRRLPRGLALTDEGLALLPAVAESLDRL
GEAVERVGQARPREVVNVGVVATFALGFLLPRLPALAAAAPQIDLRLFTNNNRVDMAGEGLDCAIRFGDGAWHGTHAERL
MDGAMTPLCAPGVARRLETPADLLGETLLRSYRAEEWTRWFALAGVPVPPLRGPVFDSSLAMAEAAEQGLGVALAPAAMF
RARIDRGALVQPFRLDAPVGGYWLTWLRSKAPTEGMLAFRAWLSEACGEAP

Sequences:

>Translated_291_residues
MVRPYLPLNGLRAFEAAARHLSFTKAAIELCVTQAAVSQQVKALEGRLGRRLFRRLPRGLALTDEGLALLPAVAESLDRL
GEAVERVGQARPREVVNVGVVATFALGFLLPRLPALAAAAPQIDLRLFTNNNRVDMAGEGLDCAIRFGDGAWHGTHAERL
MDGAMTPLCAPGVARRLETPADLLGETLLRSYRAEEWTRWFALAGVPVPPLRGPVFDSSLAMAEAAEQGLGVALAPAAMF
RARIDRGALVQPFRLDAPVGGYWLTWLRSKAPTEGMLAFRAWLSEACGEAP
>Mature_291_residues
MVRPYLPLNGLRAFEAAARHLSFTKAAIELCVTQAAVSQQVKALEGRLGRRLFRRLPRGLALTDEGLALLPAVAESLDRL
GEAVERVGQARPREVVNVGVVATFALGFLLPRLPALAAAAPQIDLRLFTNNNRVDMAGEGLDCAIRFGDGAWHGTHAERL
MDGAMTPLCAPGVARRLETPADLLGETLLRSYRAEEWTRWFALAGVPVPPLRGPVFDSSLAMAEAAEQGLGVALAPAAMF
RARIDRGALVQPFRLDAPVGGYWLTWLRSKAPTEGMLAFRAWLSEACGEAP

Specific function: This protein is a positive regulator of gene expression of beta-lactamase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=285, Percent_Identity=39.2982456140351, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786448, Length=283, Percent_Identity=32.5088339222615, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788706, Length=256, Percent_Identity=32.421875, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI145693193, Length=262, Percent_Identity=25.1908396946565, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787589, Length=140, Percent_Identity=32.8571428571429, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=25.0871080139373, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787128, Length=145, Percent_Identity=28.2758620689655, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081978, Length=144, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31397; Mature: 31397

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRPYLPLNGLRAFEAAARHLSFTKAAIELCVTQAAVSQQVKALEGRLGRRLFRRLPRGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ALTDEGLALLPAVAESLDRLGEAVERVGQARPREVVNVGVVATFALGFLLPRLPALAAAA
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQIDLRLFTNNNRVDMAGEGLDCAIRFGDGAWHGTHAERLMDGAMTPLCAPGVARRLETP
CCEEEEEEECCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCC
ADLLGETLLRSYRAEEWTRWFALAGVPVPPLRGPVFDSSLAMAEAAEQGLGVALAPAAMF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHHHHHHH
RARIDRGALVQPFRLDAPVGGYWLTWLRSKAPTEGMLAFRAWLSEACGEAP
HHHCCCCCCCCCEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVRPYLPLNGLRAFEAAARHLSFTKAAIELCVTQAAVSQQVKALEGRLGRRLFRRLPRGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ALTDEGLALLPAVAESLDRLGEAVERVGQARPREVVNVGVVATFALGFLLPRLPALAAAA
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQIDLRLFTNNNRVDMAGEGLDCAIRFGDGAWHGTHAERLMDGAMTPLCAPGVARRLETP
CCEEEEEEECCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCC
ADLLGETLLRSYRAEEWTRWFALAGVPVPPLRGPVFDSSLAMAEAAEQGLGVALAPAAMF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHHHHHHH
RARIDRGALVQPFRLDAPVGGYWLTWLRSKAPTEGMLAFRAWLSEACGEAP
HHHCCCCCCCCCEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405939; 10984043; 2125210 [H]