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The map label for this gene is dsbD [H]

Identifier: 197103795

GI number: 197103795

Start: 324256

End: 326349

Strand: Direct

Name: dsbD [H]

Synonym: PHZ_c0329

Alternate gene names: 197103795

Gene position: 324256-326349 (Clockwise)

Preceding gene: 197103794

Following gene: 197103796

Centisome position: 8.11

GC content: 75.6

Gene sequence:

>2094_bases
ATGGGGGTCTTCGCCGGCGCCGCCTTTGCGCAGCCGGTCAACACCGGCCATCTCGTCGCCGAGTTGGCGCCCCGGGCGCA
GGGGATCGCCCCCGGCCAGACGCTGCACGTGGCCCTCGTCCAGAAGATCCAGGACGGCTGGCACACCTACTGGCGCAACC
CGGGCGATTCCGGCGAGCCGACCCGCATCGAATGGACCCTGCCGCCGGGCTGGAGCGCCGGCGAGTTCGTCTGGCCGACG
CCGCACCGCCTGCCGGTCGGCCCGCTGGTCAACTACGGCTACGAGGGGCAGGTGATCCTGCCGGTCCCGGTGACCGCCCC
CGCCGACGCGGCGCCCGGCCAGACCGTCACGCTCAAGGGCCGCGCCACCTTCCTGGTGTGCGAGGAGATCTGCATCCCGG
AGAGCGCCGACCTGACGCTGTCCCTGCCGGTCGTCGCCGCCCCGGCGCCCGCCCATCCGCAGTGGGACGGGCCCATCCGC
AAGGCCCTGGCCGAGGCGCCGAAGCCCGCCGGCCTGACCGCCGCATTCCAGAAGGACGCCGCCGGCGTGAAGCTGGCCAT
CGTCGGCGCCCCGCTGAAGGGCGCGGATGTCTCGGACGCCTACTTCTTCCCCTTCTCCGGCACGGCGATCGACCACGCCA
AGCCGCAGCCGATCGAGCGCGGCGCCGAGGGTCTGACGCTCACCCTGACCCCCGGCGTCGATTTCCAGACCGGGGATCCG
CAGGACCTCTCCGGCGTCCTGTCCCTCGGCGAGACGGCCTACGAGGTGACCGCCGCCGCCGGCCCGCTTCCGGCCGCGGC
CGCCGGGCTGGGCCCGCCGCCCGCCAGGGTTTCGGGTGGCGGCGCGGGCGCGCTGAACCTCGCCACCGCCGCCCTGTTCG
GCCTGCTGGGCGGGCTGATCCTCAACCTGATGCCCTGCGTCTTCCCGGTGCTGGCCATGAAGGCCGCCTCGCTGGCCGGC
CACGGGGGCGGGGCGCACGCCGAAGCCCGCCGCCAGGGTCTGGCCTTCGGGGCCGGCGTGCTCGTGACCTTCCTCGCCCT
GGCGGGAGTGCTGATCGCCCTGAAGGCGGCCGGCTCGGCCGTCGGCTGGGGCTTCCAGCTCCAGTCCCCGCCGGTCGTCG
CCGCCCTGGCCCTCCTGATGCTGGCGGTGGCCCTGAACCTCTCGGGCGTGTTCGAGGTCGCCGGCTCGCTGCAGAACGTC
GGCTCGGGCCTCGCCCGCCGCGGCGGGACCACTGGCGCCTTCTTCACCGGCACGCTGGCGGTGGTCGTGGCGGCCCCCTG
CACCGCGCCCTTCATGGGCCCGGCGCTGGGCTGGGCCCTGACCCAGAGCGCCGCCGCCGCCCTGACCGTATTCCTGGCCC
TCGGGATCGGCTTCGCAGCGCCCTTCGTCGCCGTGGCCTTCGTCCCGGCCCTGCTGGACCGCCTGCCGACGCCGGGCGCC
TGGATGGAGACCTTCCGCAAGGCCCTGGCCTTCCCGATGTACGCCGCCGCCGCCTGGCTGGTGTGGGTGCTGGCCCAGCA
GACCGGGCCCGAGGGCCTGGCGCGCCTGCTGGCCGCCGCCATCGTCGTCGCGCTCGCCGCCTGGCTGGCCGGCATCGCCC
AGCGCCGCGCGCTCCAGGGCGGACGGCCGCTCGCCTACGGCCTGGCCGCCGGGGTCCTCGCCGTCCTGGCGCTCGCCGCG
GTGGTGGGCCCCAGGTACGCCGAGGCCGCCCAGGGGCCGGCGACCGCCTCGGCCGGCGGCGTCCCCTACGAGACCTACAG
CCCGGCCCGGCTGGCCGAGCTGCGCGCCGCCGGCACGCCGGTGTTCGTCAACTACACCGCCGCCTGGTGCGTGAGCTGCC
AGGTGAACGAGCGCGTGGCCCTCTCCACCCGGGGCGTGGCCGAGGCGCTGGAGCGCACCGGCGCCGTCTACCTCAAGGCC
GACTGGACGAAGAAGGACCCGCAGATCGCGGCCGAACTGGCCAGCTTCGGCCGCGCCGGCGTCCCGCTCTATCTCGTGTA
TGGCGCGGGCGGCGGCGAGCCCGCTATCCTTCCAGCCCTCCTGACCGAAGGCCTCGTCGTGCGCGCCATCGACGCCGCCG
CGAAGCCGAGCTGA

Upstream 100 bases:

>100_bases
GACATCCGTGGGCCATAAAGTCGCGTACATTGGTAATATCGGGTTCCTCGAAGGGGTGACGATGCGGTTCCTCGCGGGCG
TGGTGTTCGCCCTGGTCTCC

Downstream 100 bases:

>100_bases
CCCCAAGAAGAAACCTGAAGGGAGCCCTGCCGATGCCCGGAATCCTCGACCGCCGAACCGTCCTGGCCTTCGCCGCCGCC
GCGGCGCTCGCGGCGCCCGC

Product: thio:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MGVFAGAAFAQPVNTGHLVAELAPRAQGIAPGQTLHVALVQKIQDGWHTYWRNPGDSGEPTRIEWTLPPGWSAGEFVWPT
PHRLPVGPLVNYGYEGQVILPVPVTAPADAAPGQTVTLKGRATFLVCEEICIPESADLTLSLPVVAAPAPAHPQWDGPIR
KALAEAPKPAGLTAAFQKDAAGVKLAIVGAPLKGADVSDAYFFPFSGTAIDHAKPQPIERGAEGLTLTLTPGVDFQTGDP
QDLSGVLSLGETAYEVTAAAGPLPAAAAGLGPPPARVSGGGAGALNLATAALFGLLGGLILNLMPCVFPVLAMKAASLAG
HGGGAHAEARRQGLAFGAGVLVTFLALAGVLIALKAAGSAVGWGFQLQSPPVVAALALLMLAVALNLSGVFEVAGSLQNV
GSGLARRGGTTGAFFTGTLAVVVAAPCTAPFMGPALGWALTQSAAAALTVFLALGIGFAAPFVAVAFVPALLDRLPTPGA
WMETFRKALAFPMYAAAAWLVWVLAQQTGPEGLARLLAAAIVVALAAWLAGIAQRRALQGGRPLAYGLAAGVLAVLALAA
VVGPRYAEAAQGPATASAGGVPYETYSPARLAELRAAGTPVFVNYTAAWCVSCQVNERVALSTRGVAEALERTGAVYLKA
DWTKKDPQIAAELASFGRAGVPLYLVYGAGGGEPAILPALLTEGLVVRAIDAAAKPS

Sequences:

>Translated_697_residues
MGVFAGAAFAQPVNTGHLVAELAPRAQGIAPGQTLHVALVQKIQDGWHTYWRNPGDSGEPTRIEWTLPPGWSAGEFVWPT
PHRLPVGPLVNYGYEGQVILPVPVTAPADAAPGQTVTLKGRATFLVCEEICIPESADLTLSLPVVAAPAPAHPQWDGPIR
KALAEAPKPAGLTAAFQKDAAGVKLAIVGAPLKGADVSDAYFFPFSGTAIDHAKPQPIERGAEGLTLTLTPGVDFQTGDP
QDLSGVLSLGETAYEVTAAAGPLPAAAAGLGPPPARVSGGGAGALNLATAALFGLLGGLILNLMPCVFPVLAMKAASLAG
HGGGAHAEARRQGLAFGAGVLVTFLALAGVLIALKAAGSAVGWGFQLQSPPVVAALALLMLAVALNLSGVFEVAGSLQNV
GSGLARRGGTTGAFFTGTLAVVVAAPCTAPFMGPALGWALTQSAAAALTVFLALGIGFAAPFVAVAFVPALLDRLPTPGA
WMETFRKALAFPMYAAAAWLVWVLAQQTGPEGLARLLAAAIVVALAAWLAGIAQRRALQGGRPLAYGLAAGVLAVLALAA
VVGPRYAEAAQGPATASAGGVPYETYSPARLAELRAAGTPVFVNYTAAWCVSCQVNERVALSTRGVAEALERTGAVYLKA
DWTKKDPQIAAELASFGRAGVPLYLVYGAGGGEPAILPALLTEGLVVRAIDAAAKPS
>Mature_696_residues
GVFAGAAFAQPVNTGHLVAELAPRAQGIAPGQTLHVALVQKIQDGWHTYWRNPGDSGEPTRIEWTLPPGWSAGEFVWPTP
HRLPVGPLVNYGYEGQVILPVPVTAPADAAPGQTVTLKGRATFLVCEEICIPESADLTLSLPVVAAPAPAHPQWDGPIRK
ALAEAPKPAGLTAAFQKDAAGVKLAIVGAPLKGADVSDAYFFPFSGTAIDHAKPQPIERGAEGLTLTLTPGVDFQTGDPQ
DLSGVLSLGETAYEVTAAAGPLPAAAAGLGPPPARVSGGGAGALNLATAALFGLLGGLILNLMPCVFPVLAMKAASLAGH
GGGAHAEARRQGLAFGAGVLVTFLALAGVLIALKAAGSAVGWGFQLQSPPVVAALALLMLAVALNLSGVFEVAGSLQNVG
SGLARRGGTTGAFFTGTLAVVVAAPCTAPFMGPALGWALTQSAAAALTVFLALGIGFAAPFVAVAFVPALLDRLPTPGAW
METFRKALAFPMYAAAAWLVWVLAQQTGPEGLARLLAAAIVVALAAWLAGIAQRRALQGGRPLAYGLAAGVLAVLALAAV
VGPRYAEAAQGPATASAGGVPYETYSPARLAELRAAGTPVFVNYTAAWCVSCQVNERVALSTRGVAEALERTGAVYLKAD
WTKKDPQIAAELASFGRAGVPLYLVYGAGGGEPAILPALLTEGLVVRAIDAAAKPS

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=422, Percent_Identity=28.1990521327014, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 70549; Mature: 70418

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVFAGAAFAQPVNTGHLVAELAPRAQGIAPGQTLHVALVQKIQDGWHTYWRNPGDSGEP
CCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
TRIEWTLPPGWSAGEFVWPTPHRLPVGPLVNYGYEGQVILPVPVTAPADAAPGQTVTLKG
CEEEEECCCCCCCCCEECCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEC
RATFLVCEEICIPESADLTLSLPVVAAPAPAHPQWDGPIRKALAEAPKPAGLTAAFQKDA
CEEEEEEHHHCCCCCCCCEEEECEEECCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHCC
AGVKLAIVGAPLKGADVSDAYFFPFSGTAIDHAKPQPIERGAEGLTLTLTPGVDFQTGDP
CCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCCCEEEEECCCCCCCCCCC
QDLSGVLSLGETAYEVTAAAGPLPAAAAGLGPPPARVSGGGAGALNLATAALFGLLGGLI
HHHHHHHHHCCHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LNLMPCVFPVLAMKAASLAGHGGGAHAEARRQGLAFGAGVLVTFLALAGVLIALKAAGSA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VGWGFQLQSPPVVAALALLMLAVALNLSGVFEVAGSLQNVGSGLARRGGTTGAFFTGTLA
CCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
VVVAAPCTAPFMGPALGWALTQSAAAALTVFLALGIGFAAPFVAVAFVPALLDRLPTPGA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
WMETFRKALAFPMYAAAAWLVWVLAQQTGPEGLARLLAAAIVVALAAWLAGIAQRRALQG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRPLAYGLAAGVLAVLALAAVVGPRYAEAAQGPATASAGGVPYETYSPARLAELRAAGTP
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
VFVNYTAAWCVSCQVNERVALSTRGVAEALERTGAVYLKADWTKKDPQIAAELASFGRAG
EEEEEEEEEEEEEECCCEEEECHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCC
VPLYLVYGAGGGEPAILPALLTEGLVVRAIDAAAKPS
CCEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure 
GVFAGAAFAQPVNTGHLVAELAPRAQGIAPGQTLHVALVQKIQDGWHTYWRNPGDSGEP
CCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
TRIEWTLPPGWSAGEFVWPTPHRLPVGPLVNYGYEGQVILPVPVTAPADAAPGQTVTLKG
CEEEEECCCCCCCCCEECCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEC
RATFLVCEEICIPESADLTLSLPVVAAPAPAHPQWDGPIRKALAEAPKPAGLTAAFQKDA
CEEEEEEHHHCCCCCCCCEEEECEEECCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHCC
AGVKLAIVGAPLKGADVSDAYFFPFSGTAIDHAKPQPIERGAEGLTLTLTPGVDFQTGDP
CCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCCCEEEEECCCCCCCCCCC
QDLSGVLSLGETAYEVTAAAGPLPAAAAGLGPPPARVSGGGAGALNLATAALFGLLGGLI
HHHHHHHHHCCHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LNLMPCVFPVLAMKAASLAGHGGGAHAEARRQGLAFGAGVLVTFLALAGVLIALKAAGSA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VGWGFQLQSPPVVAALALLMLAVALNLSGVFEVAGSLQNVGSGLARRGGTTGAFFTGTLA
CCCCEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
VVVAAPCTAPFMGPALGWALTQSAAAALTVFLALGIGFAAPFVAVAFVPALLDRLPTPGA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
WMETFRKALAFPMYAAAAWLVWVLAQQTGPEGLARLLAAAIVVALAAWLAGIAQRRALQG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRPLAYGLAAGVLAVLALAAVVGPRYAEAAQGPATASAGGVPYETYSPARLAELRAAGTP
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
VFVNYTAAWCVSCQVNERVALSTRGVAEALERTGAVYLKADWTKKDPQIAAELASFGRAG
EEEEEEEEEEEEEECCCEEEECHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCC
VPLYLVYGAGGGEPAILPALLTEGLVVRAIDAAAKPS
CCEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA