Click here to switch to the map view.

The map label for this gene is rppH [H]

Identifier: 197103708

GI number: 197103708

Start: 244372

End: 244926

Strand: Reverse

Name: rppH [H]

Synonym: PHZ_c0242

Alternate gene names: 197103708

Gene position: 244926-244372 (Counterclockwise)

Preceding gene: 197103709

Following gene: 197103707

Centisome position: 6.13

GC content: 73.15

Gene sequence:

>555_bases
TTGGGCGAACGAGGTGGAGCAGAGGGGCTATCAGCTGGCCCCCGCCTCGGCGCTCATGGCCCGGAGATGACCGACCTATC
CCGCTACCGTCCCAATGTCGGCGTGGTGCTCTTCCATCCCGACGGCCGCGTGTGGTTGGGCCGCCGCGCCGGCGCGGCCC
CGCCCTACAACTGGCAGTTCCCGCAGGGCGGGGTGGACGACGGCGAGGAGCTGGAGGCCGCCGCCCGCCGCGAGCTCGCC
GAGGAGACCGGCGCGGTCAGCATCGCCTACCTCGGCCGCACCGACGGCTGGATCGTCTACGACTTCCCGGAGGGGATGGG
CGGGCCCAAGGCCTGGCGCGGCTTCAAGGGCCAGCGCCAGGTGTGGTTCGCCTTCCGCTTCGACGGCGAGGAGTCCGAGT
TCGACCTCGCCGCCCACCACGAGCCCGAGTTCGAGGAATGGCGCTGGGGATACCTGGCCGAGGCGCCGGACCTCGTCGTG
CCGTTCAAGCGGCAGGCCTACGAGCAGGTGGCCCGCGCCTTCGCCCCGCTGGCCGCCCGCCACGGCGGCGGCTGA

Upstream 100 bases:

>100_bases
TCGACCAGCAGCTCCTGGCGCTCGAGGCCGGCGCCCTGCAGCGCGGCCAGGCGCTGGGCTCGGGCTTCGCCTATCCGGTG
ACCCTGGAGACCGTGGCGCG

Downstream 100 bases:

>100_bases
AACCCTCCCCGCGCTCCCGCCTTTCCGTCTAGACTGCGCCCCGGACGAGAGCTCCGGGGGGAGCGAGGCGGAATGACGAC
AGTGGTGATGGCGCACGGCG

Product: MutT/nudix family protein

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MGERGGAEGLSAGPRLGAHGPEMTDLSRYRPNVGVVLFHPDGRVWLGRRAGAAPPYNWQFPQGGVDDGEELEAAARRELA
EETGAVSIAYLGRTDGWIVYDFPEGMGGPKAWRGFKGQRQVWFAFRFDGEESEFDLAAHHEPEFEEWRWGYLAEAPDLVV
PFKRQAYEQVARAFAPLAARHGGG

Sequences:

>Translated_184_residues
MGERGGAEGLSAGPRLGAHGPEMTDLSRYRPNVGVVLFHPDGRVWLGRRAGAAPPYNWQFPQGGVDDGEELEAAARRELA
EETGAVSIAYLGRTDGWIVYDFPEGMGGPKAWRGFKGQRQVWFAFRFDGEESEFDLAAHHEPEFEEWRWGYLAEAPDLVV
PFKRQAYEQVARAFAPLAARHGGG
>Mature_183_residues
GERGGAEGLSAGPRLGAHGPEMTDLSRYRPNVGVVLFHPDGRVWLGRRAGAAPPYNWQFPQGGVDDGEELEAAARRELAE
ETGAVSIAYLGRTDGWIVYDFPEGMGGPKAWRGFKGQRQVWFAFRFDGEESEFDLAAHHEPEFEEWRWGYLAEAPDLVVP
FKRQAYEQVARAFAPLAARHGGG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=158, Percent_Identity=36.0759493670886, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20360; Mature: 20229

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGERGGAEGLSAGPRLGAHGPEMTDLSRYRPNVGVVLFHPDGRVWLGRRAGAAPPYNWQF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCEEECCCCCCCCCCCCCC
PQGGVDDGEELEAAARRELAEETGAVSIAYLGRTDGWIVYDFPEGMGGPKAWRGFKGQRQ
CCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCCCHHHCCCCCCEE
VWFAFRFDGEESEFDLAAHHEPEFEEWRWGYLAEAPDLVVPFKRQAYEQVARAFAPLAAR
EEEEEEECCCCCCEEEECCCCCCHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
HGGG
CCCC
>Mature Secondary Structure 
GERGGAEGLSAGPRLGAHGPEMTDLSRYRPNVGVVLFHPDGRVWLGRRAGAAPPYNWQF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCEEECCCCCCCCCCCCCC
PQGGVDDGEELEAAARRELAEETGAVSIAYLGRTDGWIVYDFPEGMGGPKAWRGFKGQRQ
CCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCCCHHHCCCCCCEE
VWFAFRFDGEESEFDLAAHHEPEFEEWRWGYLAEAPDLVVPFKRQAYEQVARAFAPLAAR
EEEEEEECCCCCCEEEECCCCCCHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
HGGG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA