Click here to switch to the map view.

The map label for this gene is gltB [H]

Identifier: 197103630

GI number: 197103630

Start: 155882

End: 160426

Strand: Reverse

Name: gltB [H]

Synonym: PHZ_c0164

Alternate gene names: 197103630

Gene position: 160426-155882 (Counterclockwise)

Preceding gene: 197103631

Following gene: 197103628

Centisome position: 4.01

GC content: 70.36

Gene sequence:

>4545_bases
ATGACCGACATCCTGACCCGCTACGAGACCGATCGGCAGCGCCTCCTGGAGGCCAACGGCGGCTACGACATCACCGCCCA
GCACGACGCCTGCGGCGTGGGCCTCGTCTGCGCCATCGACGGCAAGCCGCGCCGCGAGGTGGTGGAGCTGGCGATCCGCG
CCCTGAAGGCCGTCTGGCACCGCGGCGCCGTGGACGCCGACGGCAAGACCGGCGACGGCGCCGGCGTGCTGGTGTCGGTC
CCGCAGGACTTCTTCGCCGCCCACGTGGAGGCGATCGGCCACAAGGTGCGCCCCGGCCCCATCGCCGTCGGCCAGGTGTT
CCTGCCGCGCACCGACCTCGCCGCCCAGGAAGCGGCCCGGACGATCGTCGAGAGCGAGGCCCTGCGCTTCGGCTTCTACA
TCTACGGCTGGCGCCAGGTGCCGACCGACACCTCGGTGATCGGCGAGAAGGCCAACGCCACCCGCCCCGAGATCGAGCAG
ATCATGCTCTCGCCGCCCCTGGGCCTGGAGGGCGAGGCGCTGGAGCGCGCCCTCTTCCTGTGCCGCAAGCGGATCGAGAA
GCGCGTGGCGCAGGCCAACATCCAGCACTTCTACATCTGCTCGCTGTCCTCGCGGTCCCTGATCTACAAGGGGATGTTCC
TCGCCGAGCACATCGACACCTTCTACCCCGACCTGAAGGACCCGCGGTTCATGGCCGCGGTGGCGATCTTCCACCAGCGC
TACTCGACCAACACCTTCCCCGAGTGGCGGCTGGCCCAGCCGTTCCGGATGCTGGCCCACAACGGCGAGATCAACACGCT
GAAGGGCAACACCAACTGGATGAAGTCGCACGAGATCCGCATGGCGGCCTCGGCGTTCGGCGACTACCAGGACGACATCA
AGCCGGTGATCCAGCCGGGCAGCTCGGACAGCTCGGCCCTCGACAACACCTTCGAGGTGCTGGTGCGCGCGGGCCGCGAC
GCGCCGATGGCCAAGACCCTGCTGATCCCCGAGGCGTGGAACACCCGCACCGACGAGCAGATGAAGGCCTCGCACCGGGC
GCTCTACGCCTACTGCAACGCGGTGATGGAGCCGTGGGACGGCCCGGCCGCCGTCTGCGCCACCGACGGCCGCTGGGTCG
TGGCCGGCAAGGACCGCAACGGCCTGCGCCCGCTGCGCGTGGCCGAGACGCGGGACGGCCTGCTGATCGTCGGCTCCGAG
GCCGGCATGTGCCGCGTCGACGAGGCCCGCATCGTGCGCAAGGCGCACATCCAGCCCGGCCGCATGCTGGCCGTGGACCT
GACCGAGGGCCGCCTCTACGCCGAGGAGGCGATCATCGACCGCCTCGCCGGCCAGCATCCCTACGACCGCTGGCTCGGCA
ACATGGTCGAGCTGGAGGAGAAGATCGGCCCCGGCCCCGAGGCGCGGATGTTCCCGCGCGAGGAGCTGGTGCGCCGCCAG
GCCGCCGCCGGCATGACGCTGGAGGACCTGGAGCTGGTCCTGGCCCCCATGGTCGAGGAGGCCAAGGAGGCGGTGGGCTC
GATGGGCGACGACACGCCGCTGGCCGTGCTGTCGAACGAATACCGGCCGCTGTCGCACTTCTTCCGGCAGAACTTCAGCC
AGGTGACCAACCCGCCGATCGACTCGCTGCGCGAGACGGCGGTGATGAGCCTGAAGACCCGCTTCAAGAACCTGGGCAAC
GTCCTGGCCGAGGACGAGACCCAGACGGACGTGTTCGTGCTGAACTCGCCCGTGCTGACCAACGGCATGTACGAGCGCGT
GGTCGGGGTCATCGGCGAGAAGAACATCGCCGAGATCGACTGCACCATGCCGATCCCCGGCGAGGACGCCCGGTCGGGCG
AGGCCCTGCGGGCCAACCTCGACCGCATCCGCGCCGAGGCCGAGGAGGCCGCCCTGCGCGGCTGCTCGACCATCGTGCTG
ACCGACACCGCGACCGGTCCCGAACGGGTCGCCCTGCCGATGATCCTGGCCACCGGCGGCGTCCACGCCTGGCTCGTCGC
CAAGGGCCTGCGCAGCTACGTCTCGATCATCGTGCGCTCGGCGGAGTGCCTCGACACCCACTACTTCGCGGTGCTGGTCG
GCGTCGGCGCGACGGCGGTGAACGCCTACCTCGCCCAGGAGAGCTTCCTCGACCGCCAGGAGCGCGGCCTGACAGGCGAG
CTGTCGCTGCGCGAGCTGTGCCTGAACCACAAGAAGGCCATCGAGGGCGGCCTCCTGAAGATCATCTCCAAGATGGGGAT
CAGCGTCATCTCCTCGTACCGCGGCGGCTACAACTTCGAGGCCGTCGGCCTGTCGCGCTCGCTCGTGGCCGAGTTCTTCC
CGGGCATGCCCTCGCGCATCTCCGGCATCGGCCTGGCCGGCCTGGAGGCCAAGGCGGTCGACCTGCACCGCCGCGCCTGG
AACCCCGCGGCCCTCTCCCTGCCGGTCGGCGGCTTCTACAAGTCGCGGCGCGCGGGCGAGGCGCACGCCTTCGAGGCGCG
CTCGATCCACACCCTCCAGAGCGCCTGCGACCGCGGCGACTACCAGCTCTACAAGCGCTACTCCGAGGCCATGCGGGCGA
TGCCGCAGATCCAGCTGCGCGACCTGCTGGAGTGGCGGGCCGAGGGCCGGCCGGTGGACATCGACGAGGTCGAGAGCGTC
AACGAGATCCGCAAGCGCTTCGTCACGCCGGGCATGAGCCTGGGGGCGCTGAGCCCCGAAGCCCATGGCGCGCTGAACAT
CGCCATGAACCGCATCGGCGCGAAGTCGGTCTCGGGCGAGGGCGGCGAGGACCGGGCGCGCTACAAGCCCCTGCCGAACG
GCGACAACCCCAACTCGGCGGTCAAGCAGATCGCCTCGGGCCGGTTCGGCGTCACCGCCGAGTACCTGAACCAGTGCCGC
GAGATCGAGATCAAGGTGAGCCAGGGCGCCAAGCCCGGCGAGGGCGGCCAGCTGCCCGGCTTCAAGGTCACCGAGATGAT
CGCCCGGCTGCGGCACGCCACCCCCGGGGTGATGCTGATCAGCCCGCCGCCGCACCACGACATCTATTCGATCGAGGACC
TGGCCCAGCTCATCTACGATCTGAAGCAGATCAACCCCGACGCCCGGGTGACCGTGAAGCTGGTCGCCATGACCGGCATC
GGCGCGATCGCGGCGGGCGTGGCCAAGGCCAAGGCGGACATCATCCTGATCTCGGGCAACGTCGGCGGCACCGGCGCCTC
GCCCCAGACCTCGATCAAGTACGCCGGGGGCCCGTGGGAAATGGGCCTGTCCGAGGCGCACCAGGTCCTGACCCTGAACA
ACCTGCGCCACTTCGTGCGCCTGCGCACCGACGGCGGCATCCGCTCGGGCCGGGACGTGGTGATCGCGGCCATGCTGGGG
GCCGAGGAGTTCGGCATCGGCACCGCCAGCCTGATCGCCATGGGCTGCATCATGGTGCGCCAGTGCCACTCCAACACCTG
CCCGGTGGGGGTCTGCACCCAGGACGAGGCCCTCCGCGCCAAGTTCACCGGCACGCCCGAGAAGGTGATCAACCTCTTCA
CCTTCATCGCCGAGGAGGTGCGCGAGATCCTGGCCTCGATCGGGGCCCGCTCGCTGCAGGAGATCGTCGGCCGCACCGAC
CTGCTGATGCAGGTCTCGCGCGGCGGCGAGCACCTGGACGACCTCGACCTCAACCCGCTGCTGGTGAAGGCCGACCCGGG
TGCGAACAAGCCCTATTGCACCATCGTCGGCCGCAACGAGGTGCCCGACACCCTCGACGCCCAGATCGTCCGCGACGCCG
CCCCGGTGTTCGACCGCGGCGAGAAGATGCAGCTCACCTACACCGTGGCCAACACCGCCCGGGCCATCGGCACCCGCACC
TCGTCGATGATCGTGCGCAAGTACGGCATGGACGGCCTGGCGCCCGGCCACCTGACGGTCCAGCTCAAGGGCTCGGCCGG
CCAGAGCCTGGGAGCCTTCGCGGTCCAGGGGCTGCGGCTGGAGGTGACCGGCGAGGCCAATGACTACGTCGGCAAGGGCC
TGTCGGGGGCGACCATCGTGGTGAAGCCCTCGCCGCATCTGGCGCCCGACGCCCGGCGCAACGCGATCATCGGCAACACC
GTGCTCTACGGCGCGACCTCGGGCCGGCTGTTCGCCGCGGGCCTGGCCGGCGAGCGCTTCGCGGTGCGCAACTCGGGGGC
GACGACCGTCGTCGAGGGCTGCGGCGCCAACGGGCTGGAATACATGACCGGCGGCACGGCCGTGATCCTTGGGCCCGTGG
GCTTCAACTTCGCGGCCGGCATGACCGGCGGCATGGCCTTCGTGCTGGACGACGCCGGCGACTTCCACGCCTCCCTCAAC
GCCGAGAGCGTGGTCACCTGCCGGGTCGCCAGCGCCCACTGGCAGGGCGTGCTGAAGGACCTGATCGAGGAGCACGCCCG
CGAGACCGGCTCGGCCCTGGCCCAGGACCTGCTGCGCAACTGGGACGAGGCCCTCGGCCGCTTCTGGCAGGTCTGCCCCA
AGGAGATGGTCGGCCGCCTCGACCATGCCCTGGAGGCCGAGGAGGTCGTGCATAGGCGGGCCTAG

Upstream 100 bases:

>100_bases
TGGTGTGGGCGATCCGCGACGGACGCGACGCCGCCGAGGCCATGCACCGCTACCTGACCGCCCACGCTGGGGCCGCCCTG
ATGGCGGCGGAGTGACGCCG

Downstream 100 bases:

>100_bases
AGCCAGGACTCCTCCCCCTCAGGAGGAGGGGGAGGACGTCACACCAGCTCAGGCTCCGGGCCCACGTAGCGGGCCCGCGG
GCGGATGAGGGCGTCGGTCT

Product: glutamate synthase, large subunit

Products: NA

Alternate protein names: Glutamate synthase subunit alpha; GLTS alpha chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 1514; Mature: 1513

Protein sequence:

>1514_residues
MTDILTRYETDRQRLLEANGGYDITAQHDACGVGLVCAIDGKPRREVVELAIRALKAVWHRGAVDADGKTGDGAGVLVSV
PQDFFAAHVEAIGHKVRPGPIAVGQVFLPRTDLAAQEAARTIVESEALRFGFYIYGWRQVPTDTSVIGEKANATRPEIEQ
IMLSPPLGLEGEALERALFLCRKRIEKRVAQANIQHFYICSLSSRSLIYKGMFLAEHIDTFYPDLKDPRFMAAVAIFHQR
YSTNTFPEWRLAQPFRMLAHNGEINTLKGNTNWMKSHEIRMAASAFGDYQDDIKPVIQPGSSDSSALDNTFEVLVRAGRD
APMAKTLLIPEAWNTRTDEQMKASHRALYAYCNAVMEPWDGPAAVCATDGRWVVAGKDRNGLRPLRVAETRDGLLIVGSE
AGMCRVDEARIVRKAHIQPGRMLAVDLTEGRLYAEEAIIDRLAGQHPYDRWLGNMVELEEKIGPGPEARMFPREELVRRQ
AAAGMTLEDLELVLAPMVEEAKEAVGSMGDDTPLAVLSNEYRPLSHFFRQNFSQVTNPPIDSLRETAVMSLKTRFKNLGN
VLAEDETQTDVFVLNSPVLTNGMYERVVGVIGEKNIAEIDCTMPIPGEDARSGEALRANLDRIRAEAEEAALRGCSTIVL
TDTATGPERVALPMILATGGVHAWLVAKGLRSYVSIIVRSAECLDTHYFAVLVGVGATAVNAYLAQESFLDRQERGLTGE
LSLRELCLNHKKAIEGGLLKIISKMGISVISSYRGGYNFEAVGLSRSLVAEFFPGMPSRISGIGLAGLEAKAVDLHRRAW
NPAALSLPVGGFYKSRRAGEAHAFEARSIHTLQSACDRGDYQLYKRYSEAMRAMPQIQLRDLLEWRAEGRPVDIDEVESV
NEIRKRFVTPGMSLGALSPEAHGALNIAMNRIGAKSVSGEGGEDRARYKPLPNGDNPNSAVKQIASGRFGVTAEYLNQCR
EIEIKVSQGAKPGEGGQLPGFKVTEMIARLRHATPGVMLISPPPHHDIYSIEDLAQLIYDLKQINPDARVTVKLVAMTGI
GAIAAGVAKAKADIILISGNVGGTGASPQTSIKYAGGPWEMGLSEAHQVLTLNNLRHFVRLRTDGGIRSGRDVVIAAMLG
AEEFGIGTASLIAMGCIMVRQCHSNTCPVGVCTQDEALRAKFTGTPEKVINLFTFIAEEVREILASIGARSLQEIVGRTD
LLMQVSRGGEHLDDLDLNPLLVKADPGANKPYCTIVGRNEVPDTLDAQIVRDAAPVFDRGEKMQLTYTVANTARAIGTRT
SSMIVRKYGMDGLAPGHLTVQLKGSAGQSLGAFAVQGLRLEVTGEANDYVGKGLSGATIVVKPSPHLAPDARRNAIIGNT
VLYGATSGRLFAAGLAGERFAVRNSGATTVVEGCGANGLEYMTGGTAVILGPVGFNFAAGMTGGMAFVLDDAGDFHASLN
AESVVTCRVASAHWQGVLKDLIEEHARETGSALAQDLLRNWDEALGRFWQVCPKEMVGRLDHALEAEEVVHRRA

Sequences:

>Translated_1514_residues
MTDILTRYETDRQRLLEANGGYDITAQHDACGVGLVCAIDGKPRREVVELAIRALKAVWHRGAVDADGKTGDGAGVLVSV
PQDFFAAHVEAIGHKVRPGPIAVGQVFLPRTDLAAQEAARTIVESEALRFGFYIYGWRQVPTDTSVIGEKANATRPEIEQ
IMLSPPLGLEGEALERALFLCRKRIEKRVAQANIQHFYICSLSSRSLIYKGMFLAEHIDTFYPDLKDPRFMAAVAIFHQR
YSTNTFPEWRLAQPFRMLAHNGEINTLKGNTNWMKSHEIRMAASAFGDYQDDIKPVIQPGSSDSSALDNTFEVLVRAGRD
APMAKTLLIPEAWNTRTDEQMKASHRALYAYCNAVMEPWDGPAAVCATDGRWVVAGKDRNGLRPLRVAETRDGLLIVGSE
AGMCRVDEARIVRKAHIQPGRMLAVDLTEGRLYAEEAIIDRLAGQHPYDRWLGNMVELEEKIGPGPEARMFPREELVRRQ
AAAGMTLEDLELVLAPMVEEAKEAVGSMGDDTPLAVLSNEYRPLSHFFRQNFSQVTNPPIDSLRETAVMSLKTRFKNLGN
VLAEDETQTDVFVLNSPVLTNGMYERVVGVIGEKNIAEIDCTMPIPGEDARSGEALRANLDRIRAEAEEAALRGCSTIVL
TDTATGPERVALPMILATGGVHAWLVAKGLRSYVSIIVRSAECLDTHYFAVLVGVGATAVNAYLAQESFLDRQERGLTGE
LSLRELCLNHKKAIEGGLLKIISKMGISVISSYRGGYNFEAVGLSRSLVAEFFPGMPSRISGIGLAGLEAKAVDLHRRAW
NPAALSLPVGGFYKSRRAGEAHAFEARSIHTLQSACDRGDYQLYKRYSEAMRAMPQIQLRDLLEWRAEGRPVDIDEVESV
NEIRKRFVTPGMSLGALSPEAHGALNIAMNRIGAKSVSGEGGEDRARYKPLPNGDNPNSAVKQIASGRFGVTAEYLNQCR
EIEIKVSQGAKPGEGGQLPGFKVTEMIARLRHATPGVMLISPPPHHDIYSIEDLAQLIYDLKQINPDARVTVKLVAMTGI
GAIAAGVAKAKADIILISGNVGGTGASPQTSIKYAGGPWEMGLSEAHQVLTLNNLRHFVRLRTDGGIRSGRDVVIAAMLG
AEEFGIGTASLIAMGCIMVRQCHSNTCPVGVCTQDEALRAKFTGTPEKVINLFTFIAEEVREILASIGARSLQEIVGRTD
LLMQVSRGGEHLDDLDLNPLLVKADPGANKPYCTIVGRNEVPDTLDAQIVRDAAPVFDRGEKMQLTYTVANTARAIGTRT
SSMIVRKYGMDGLAPGHLTVQLKGSAGQSLGAFAVQGLRLEVTGEANDYVGKGLSGATIVVKPSPHLAPDARRNAIIGNT
VLYGATSGRLFAAGLAGERFAVRNSGATTVVEGCGANGLEYMTGGTAVILGPVGFNFAAGMTGGMAFVLDDAGDFHASLN
AESVVTCRVASAHWQGVLKDLIEEHARETGSALAQDLLRNWDEALGRFWQVCPKEMVGRLDHALEAEEVVHRRA
>Mature_1513_residues
TDILTRYETDRQRLLEANGGYDITAQHDACGVGLVCAIDGKPRREVVELAIRALKAVWHRGAVDADGKTGDGAGVLVSVP
QDFFAAHVEAIGHKVRPGPIAVGQVFLPRTDLAAQEAARTIVESEALRFGFYIYGWRQVPTDTSVIGEKANATRPEIEQI
MLSPPLGLEGEALERALFLCRKRIEKRVAQANIQHFYICSLSSRSLIYKGMFLAEHIDTFYPDLKDPRFMAAVAIFHQRY
STNTFPEWRLAQPFRMLAHNGEINTLKGNTNWMKSHEIRMAASAFGDYQDDIKPVIQPGSSDSSALDNTFEVLVRAGRDA
PMAKTLLIPEAWNTRTDEQMKASHRALYAYCNAVMEPWDGPAAVCATDGRWVVAGKDRNGLRPLRVAETRDGLLIVGSEA
GMCRVDEARIVRKAHIQPGRMLAVDLTEGRLYAEEAIIDRLAGQHPYDRWLGNMVELEEKIGPGPEARMFPREELVRRQA
AAGMTLEDLELVLAPMVEEAKEAVGSMGDDTPLAVLSNEYRPLSHFFRQNFSQVTNPPIDSLRETAVMSLKTRFKNLGNV
LAEDETQTDVFVLNSPVLTNGMYERVVGVIGEKNIAEIDCTMPIPGEDARSGEALRANLDRIRAEAEEAALRGCSTIVLT
DTATGPERVALPMILATGGVHAWLVAKGLRSYVSIIVRSAECLDTHYFAVLVGVGATAVNAYLAQESFLDRQERGLTGEL
SLRELCLNHKKAIEGGLLKIISKMGISVISSYRGGYNFEAVGLSRSLVAEFFPGMPSRISGIGLAGLEAKAVDLHRRAWN
PAALSLPVGGFYKSRRAGEAHAFEARSIHTLQSACDRGDYQLYKRYSEAMRAMPQIQLRDLLEWRAEGRPVDIDEVESVN
EIRKRFVTPGMSLGALSPEAHGALNIAMNRIGAKSVSGEGGEDRARYKPLPNGDNPNSAVKQIASGRFGVTAEYLNQCRE
IEIKVSQGAKPGEGGQLPGFKVTEMIARLRHATPGVMLISPPPHHDIYSIEDLAQLIYDLKQINPDARVTVKLVAMTGIG
AIAAGVAKAKADIILISGNVGGTGASPQTSIKYAGGPWEMGLSEAHQVLTLNNLRHFVRLRTDGGIRSGRDVVIAAMLGA
EEFGIGTASLIAMGCIMVRQCHSNTCPVGVCTQDEALRAKFTGTPEKVINLFTFIAEEVREILASIGARSLQEIVGRTDL
LMQVSRGGEHLDDLDLNPLLVKADPGANKPYCTIVGRNEVPDTLDAQIVRDAAPVFDRGEKMQLTYTVANTARAIGTRTS
SMIVRKYGMDGLAPGHLTVQLKGSAGQSLGAFAVQGLRLEVTGEANDYVGKGLSGATIVVKPSPHLAPDARRNAIIGNTV
LYGATSGRLFAAGLAGERFAVRNSGATTVVEGCGANGLEYMTGGTAVILGPVGFNFAAGMTGGMAFVLDDAGDFHASLNA
ESVVTCRVASAHWQGVLKDLIEEHARETGSALAQDLLRNWDEALGRFWQVCPKEMVGRLDHALEAEEVVHRRA

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=1485, Percent_Identity=44.983164983165, Blast_Score=1165, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570289, Length=1535, Percent_Identity=41.4332247557003, Blast_Score=1057, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320030, Length=1526, Percent_Identity=40.5635648754915, Blast_Score=1095, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574881, Length=1527, Percent_Identity=41.7157825802227, Blast_Score=1107, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665539, Length=1527, Percent_Identity=41.7157825802227, Blast_Score=1107, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665547, Length=381, Percent_Identity=43.3070866141732, Blast_Score=298, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24665543, Length=381, Percent_Identity=43.3070866141732, Blast_Score=298, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR002932
- InterPro:   IPR006982
- InterPro:   IPR002489 [H]

Pfam domain/function: PF00310 GATase_2; PF04898 Glu_syn_central; PF01645 Glu_synthase; PF01493 GXGXG [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 164213; Mature: 164082

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDILTRYETDRQRLLEANGGYDITAQHDACGVGLVCAIDGKPRREVVELAIRALKAVWH
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
RGAVDADGKTGDGAGVLVSVPQDFFAAHVEAIGHKVRPGPIAVGQVFLPRTDLAAQEAAR
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEECEEECCCCHHHHHHHHH
TIVESEALRFGFYIYGWRQVPTDTSVIGEKANATRPEIEQIMLSPPLGLEGEALERALFL
HHHHHHHHHEEEEEEEEEECCCCHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHH
CRKRIEKRVAQANIQHFYICSLSSRSLIYKGMFLAEHIDTFYPDLKDPRFMAAVAIFHQR
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
YSTNTFPEWRLAQPFRMLAHNGEINTLKGNTNWMKSHEIRMAASAFGDYQDDIKPVIQPG
HCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCC
SSDSSALDNTFEVLVRAGRDAPMAKTLLIPEAWNTRTDEQMKASHRALYAYCNAVMEPWD
CCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
GPAAVCATDGRWVVAGKDRNGLRPLRVAETRDGLLIVGSEAGMCRVDEARIVRKAHIQPG
CCEEEEECCCEEEEEECCCCCCCCEEEEECCCCEEEEECCCCCEECHHHHHHHHHCCCCC
RMLAVDLTEGRLYAEEAIIDRLAGQHPYDRWLGNMVELEEKIGPGPEARMFPREELVRRQ
CEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AAAGMTLEDLELVLAPMVEEAKEAVGSMGDDTPLAVLSNEYRPLSHFFRQNFSQVTNPPI
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCH
DSLRETAVMSLKTRFKNLGNVLAEDETQTDVFVLNSPVLTNGMYERVVGVIGEKNIAEID
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCHHHHHHHHHHCCCCCEEEE
CTMPIPGEDARSGEALRANLDRIRAEAEEAALRGCSTIVLTDTATGPERVALPMILATGG
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEHEEECCC
VHAWLVAKGLRSYVSIIVRSAECLDTHYFAVLVGVGATAVNAYLAQESFLDRQERGLTGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
LSLRELCLNHKKAIEGGLLKIISKMGISVISSYRGGYNFEAVGLSRSLVAEFFPGMPSRI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCHH
SGIGLAGLEAKAVDLHRRAWNPAALSLPVGGFYKSRRAGEAHAFEARSIHTLQSACDRGD
CCCCCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
YQLYKRYSEAMRAMPQIQLRDLLEWRAEGRPVDIDEVESVNEIRKRFVTPGMSLGALSPE
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
AHGALNIAMNRIGAKSVSGEGGEDRARYKPLPNGDNPNSAVKQIASGRFGVTAEYLNQCR
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCC
EIEIKVSQGAKPGEGGQLPGFKVTEMIARLRHATPGVMLISPPPHHDIYSIEDLAQLIYD
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHH
LKQINPDARVTVKLVAMTGIGAIAAGVAKAKADIILISGNVGGTGASPQTSIKYAGGPWE
HHHCCCCCEEEEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCHH
MGLSEAHQVLTLNNLRHFVRLRTDGGIRSGRDVVIAAMLGAEEFGIGTASLIAMGCIMVR
CCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHH
QCHSNTCPVGVCTQDEALRAKFTGTPEKVINLFTFIAEEVREILASIGARSLQEIVGRTD
HHCCCCCCEEEECCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHH
LLMQVSRGGEHLDDLDLNPLLVKADPGANKPYCTIVGRNEVPDTLDAQIVRDAAPVFDRG
HHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHCHHHCCC
EKMQLTYTVANTARAIGTRTSSMIVRKYGMDGLAPGHLTVQLKGSAGQSLGAFAVQGLRL
CEEEEEEEEHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHCCEEE
EVTGEANDYVGKGLSGATIVVKPSPHLAPDARRNAIIGNTVLYGATSGRLFAAGLAGERF
EEECCCCHHHCCCCCCCEEEECCCCCCCCCCCCCEEECCEEEEECCCCCEEEECCCCCEE
AVRNSGATTVVEGCGANGLEYMTGGTAVILGPVGFNFAAGMTGGMAFVLDDAGDFHASLN
EEECCCCCEEEECCCCCCCEEECCCCEEEECCCCCCHHCCCCCCEEEEEECCCCCEECCC
AESVVTCRVASAHWQGVLKDLIEEHARETGSALAQDLLRNWDEALGRFWQVCPKEMVGRL
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
DHALEAEEVVHRRA
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TDILTRYETDRQRLLEANGGYDITAQHDACGVGLVCAIDGKPRREVVELAIRALKAVWH
CCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
RGAVDADGKTGDGAGVLVSVPQDFFAAHVEAIGHKVRPGPIAVGQVFLPRTDLAAQEAAR
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEECEEECCCCHHHHHHHHH
TIVESEALRFGFYIYGWRQVPTDTSVIGEKANATRPEIEQIMLSPPLGLEGEALERALFL
HHHHHHHHHEEEEEEEEEECCCCHHHHCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHH
CRKRIEKRVAQANIQHFYICSLSSRSLIYKGMFLAEHIDTFYPDLKDPRFMAAVAIFHQR
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
YSTNTFPEWRLAQPFRMLAHNGEINTLKGNTNWMKSHEIRMAASAFGDYQDDIKPVIQPG
HCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCC
SSDSSALDNTFEVLVRAGRDAPMAKTLLIPEAWNTRTDEQMKASHRALYAYCNAVMEPWD
CCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
GPAAVCATDGRWVVAGKDRNGLRPLRVAETRDGLLIVGSEAGMCRVDEARIVRKAHIQPG
CCEEEEECCCEEEEEECCCCCCCCEEEEECCCCEEEEECCCCCEECHHHHHHHHHCCCCC
RMLAVDLTEGRLYAEEAIIDRLAGQHPYDRWLGNMVELEEKIGPGPEARMFPREELVRRQ
CEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AAAGMTLEDLELVLAPMVEEAKEAVGSMGDDTPLAVLSNEYRPLSHFFRQNFSQVTNPPI
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCH
DSLRETAVMSLKTRFKNLGNVLAEDETQTDVFVLNSPVLTNGMYERVVGVIGEKNIAEID
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCHHHHHHHHHHCCCCCEEEE
CTMPIPGEDARSGEALRANLDRIRAEAEEAALRGCSTIVLTDTATGPERVALPMILATGG
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEHEEECCC
VHAWLVAKGLRSYVSIIVRSAECLDTHYFAVLVGVGATAVNAYLAQESFLDRQERGLTGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
LSLRELCLNHKKAIEGGLLKIISKMGISVISSYRGGYNFEAVGLSRSLVAEFFPGMPSRI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCHH
SGIGLAGLEAKAVDLHRRAWNPAALSLPVGGFYKSRRAGEAHAFEARSIHTLQSACDRGD
CCCCCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
YQLYKRYSEAMRAMPQIQLRDLLEWRAEGRPVDIDEVESVNEIRKRFVTPGMSLGALSPE
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
AHGALNIAMNRIGAKSVSGEGGEDRARYKPLPNGDNPNSAVKQIASGRFGVTAEYLNQCR
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCC
EIEIKVSQGAKPGEGGQLPGFKVTEMIARLRHATPGVMLISPPPHHDIYSIEDLAQLIYD
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHH
LKQINPDARVTVKLVAMTGIGAIAAGVAKAKADIILISGNVGGTGASPQTSIKYAGGPWE
HHHCCCCCEEEEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCHH
MGLSEAHQVLTLNNLRHFVRLRTDGGIRSGRDVVIAAMLGAEEFGIGTASLIAMGCIMVR
CCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHH
QCHSNTCPVGVCTQDEALRAKFTGTPEKVINLFTFIAEEVREILASIGARSLQEIVGRTD
HHCCCCCCEEEECCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHH
LLMQVSRGGEHLDDLDLNPLLVKADPGANKPYCTIVGRNEVPDTLDAQIVRDAAPVFDRG
HHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHCHHHCCC
EKMQLTYTVANTARAIGTRTSSMIVRKYGMDGLAPGHLTVQLKGSAGQSLGAFAVQGLRL
CEEEEEEEEHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHCCEEE
EVTGEANDYVGKGLSGATIVVKPSPHLAPDARRNAIIGNTVLYGATSGRLFAAGLAGERF
EEECCCCHHHCCCCCCCEEEECCCCCCCCCCCCCEEECCEEEEECCCCCEEEECCCCCEE
AVRNSGATTVVEGCGANGLEYMTGGTAVILGPVGFNFAAGMTGGMAFVLDDAGDFHASLN
EEECCCCCEEEECCCCCCCEEECCCCEEEECCCCCCHHCCCCCCEEEEEECCCCCEECCC
AESVVTCRVASAHWQGVLKDLIEEHARETGSALAQDLLRNWDEALGRFWQVCPKEMVGRL
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
DHALEAEEVVHRRA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428988; 7902833; 2198943 [H]