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The map label for this gene is sucD [H]

Identifier: 197103625

GI number: 197103625

Start: 148147

End: 149025

Strand: Direct

Name: sucD [H]

Synonym: PHZ_c0159

Alternate gene names: 197103625

Gene position: 148147-149025 (Clockwise)

Preceding gene: 197103624

Following gene: 197103626

Centisome position: 3.71

GC content: 67.35

Gene sequence:

>879_bases
ATGTCGATCCTTATCGGTAAGGACACCCGCGTCATCTGCCAGGGCATCACCGGCAGCCAGGGCACCTTCCACACCGAACA
GGCCATCGCCTACGGGACCAAGATGGTCGGCGGCGTCACGCCGGGCAAAGGCGGCCAGACGCACGTCGGCCTGCCCGTGT
TCGACACCGTCGCCGAGGCGGTGAAGGAGACCGGCGCCGAGGCCAGCGTGATCTACGTGCCGCCGCCGTTCGCCGCGGAC
TCCATCCTCGAGGCGATCGACGCCGAGGTGCCGCTGATCGTCTGCATCACCGAGGGCATCCCGGTGACCGACATGATCAA
GGTCAAGCGCGCGCTCTCGGGCTCGAAGAGCCGGCTGATCGGGCCGAACTGCCCGGGCGTGCTGACGCCTGGCGAGTGCA
AGATCGGCATCATGCCGGGCAACATCTTCAAGCGCGGCTCGGTGGGCGTTGTTTCCCGCTCGGGCACGCTTACCTATGAG
GCCGTGTTCCAGACCACGCAGGTGGGCCTCGGCCAGACGACGGCCGTCGGCATCGGCGGCGACCCCGTCAAGGGCACCGA
GTTCATCGACGTGCTGGACATGTTCCTGAAGGACCCCGAGACCGAGTCGATCATCATGATCGGCGAGATCGGCGGCTCCG
CCGAGGAAGACGCGGCCGAGTTCATCAAGAATTCAGCTATCAAGAAGCCTATGGTCGGCTTCATCGCGGGACGCACGGCG
CCTCCGGGCCGCCGCATGGGTCACGCGGGCGCGATCATCTCCGGCGGCAAGGGCGGAGCCGAGGACAAGATCGCCGCGAT
GGAAGCCGCGGGCATCCGCGTCTCGCCGTCGCCGGCGAAACTCGGCGAGACCCTGGTCGAGGTGCTGAAGGGCGCCTGA

Upstream 100 bases:

>100_bases
AAGATCATCAACGAGAGCGGCCTGAACGTGATCGCCGCGAACGATCTGTCGGACGGAGCCGAGAAGATCGTGAAGGCCGT
CCGGGGGGCTGCGTAAGAGA

Downstream 100 bases:

>100_bases
GGGACGATATTTTAGCGTAAGGGCGGTTCGCGCCGGCGCCTTCTCGAAAAGGTCCGCGGACCGGCCCGGAAGGCGGAGAC
ATGGCGGACGACGCAGGCCT

Product: succinyl-CoA synthetase alpha-subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSILIGKDTRVICQGITGSQGTFHTEQAIAYGTKMVGGVTPGKGGQTHVGLPVFDTVAEAVKETGAEASVIYVPPPFAAD
SILEAIDAEVPLIVCITEGIPVTDMIKVKRALSGSKSRLIGPNCPGVLTPGECKIGIMPGNIFKRGSVGVVSRSGTLTYE
AVFQTTQVGLGQTTAVGIGGDPVKGTEFIDVLDMFLKDPETESIIMIGEIGGSAEEDAAEFIKNSAIKKPMVGFIAGRTA
PPGRRMGHAGAIISGGKGGAEDKIAAMEAAGIRVSPSPAKLGETLVEVLKGA

Sequences:

>Translated_292_residues
MSILIGKDTRVICQGITGSQGTFHTEQAIAYGTKMVGGVTPGKGGQTHVGLPVFDTVAEAVKETGAEASVIYVPPPFAAD
SILEAIDAEVPLIVCITEGIPVTDMIKVKRALSGSKSRLIGPNCPGVLTPGECKIGIMPGNIFKRGSVGVVSRSGTLTYE
AVFQTTQVGLGQTTAVGIGGDPVKGTEFIDVLDMFLKDPETESIIMIGEIGGSAEEDAAEFIKNSAIKKPMVGFIAGRTA
PPGRRMGHAGAIISGGKGGAEDKIAAMEAAGIRVSPSPAKLGETLVEVLKGA
>Mature_291_residues
SILIGKDTRVICQGITGSQGTFHTEQAIAYGTKMVGGVTPGKGGQTHVGLPVFDTVAEAVKETGAEASVIYVPPPFAADS
ILEAIDAEVPLIVCITEGIPVTDMIKVKRALSGSKSRLIGPNCPGVLTPGECKIGIMPGNIFKRGSVGVVSRSGTLTYEA
VFQTTQVGLGQTTAVGIGGDPVKGTEFIDVLDMFLKDPETESIIMIGEIGGSAEEDAAEFIKNSAIKKPMVGFIAGRTAP
PGRRMGHAGAIISGGKGGAEDKIAAMEAAGIRVSPSPAKLGETLVEVLKGA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=289, Percent_Identity=68.5121107266436, Blast_Score=347, Evalue=9e-96,
Organism=Homo sapiens, GI38569423, Length=259, Percent_Identity=30.1158301158301, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI38569421, Length=259, Percent_Identity=30.1158301158301, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=70.6896551724138, Blast_Score=404, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17550194, Length=294, Percent_Identity=64.2857142857143, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17553126, Length=294, Percent_Identity=62.9251700680272, Blast_Score=350, Evalue=6e-97,
Organism=Caenorhabditis elegans, GI17557344, Length=263, Percent_Identity=28.8973384030418, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551266, Length=258, Percent_Identity=28.6821705426357, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=53.7414965986395, Blast_Score=300, Evalue=2e-82,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=61.3793103448276, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=68.259385665529, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI281363477, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363475, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281363473, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29890; Mature: 29759

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIGKDTRVICQGITGSQGTFHTEQAIAYGTKMVGGVTPGKGGQTHVGLPVFDTVAEA
CEEEECCCCEEEEECCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHH
VKETGAEASVIYVPPPFAADSILEAIDAEVPLIVCITEGIPVTDMIKVKRALSGSKSRLI
HHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVLTPGECKIGIMPGNIFKRGSVGVVSRSGTLTYEAVFQTTQVGLGQTTAVGIGG
CCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCEEEHHHHHHHHCCCCCEEEEECCC
DPVKGTEFIDVLDMFLKDPETESIIMIGEIGGSAEEDAAEFIKNSAIKKPMVGFIAGRTA
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCC
PPGRRMGHAGAIISGGKGGAEDKIAAMEAAGIRVSPSPAKLGETLVEVLKGA
CCCCCCCCCCEEEECCCCCCCCHHHHHHHCCEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILIGKDTRVICQGITGSQGTFHTEQAIAYGTKMVGGVTPGKGGQTHVGLPVFDTVAEA
EEEECCCCEEEEECCCCCCCCEEHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHH
VKETGAEASVIYVPPPFAADSILEAIDAEVPLIVCITEGIPVTDMIKVKRALSGSKSRLI
HHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVLTPGECKIGIMPGNIFKRGSVGVVSRSGTLTYEAVFQTTQVGLGQTTAVGIGG
CCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCEEEHHHHHHHHCCCCCEEEEECCC
DPVKGTEFIDVLDMFLKDPETESIIMIGEIGGSAEEDAAEFIKNSAIKKPMVGFIAGRTA
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCC
PPGRRMGHAGAIISGGKGGAEDKIAAMEAAGIRVSPSPAKLGETLVEVLKGA
CCCCCCCCCCEEEECCCCCCCCHHHHHHHCCEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]