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The map label for this gene is ccmA [H]

Identifier: 197103606

GI number: 197103606

Start: 130072

End: 130674

Strand: Reverse

Name: ccmA [H]

Synonym: PHZ_c0140

Alternate gene names: 197103606

Gene position: 130674-130072 (Counterclockwise)

Preceding gene: 197103610

Following gene: 197103605

Centisome position: 3.27

GC content: 76.29

Gene sequence:

>603_bases
ATGATATCGGAGCTGGTCATTTCCGACGCGTCCGTCCGGCGTGGCGGGCGGGTGCTGTTCGAGGGGCTGGGGCTGACGCT
CGCGGCCGGCCAGGCCTGCGCGCTGACCGGGCCGAACGGCTCGGGCAAGACCAGCCTGTTGCGGGCGATCGCCGGACTCG
TGCGCCTGGAAGCGGGGGAGATCGGCTTCGGCGGGGCCGAACCGGCCGAGGCGCGGGCCGCGGCCGTGCACTTCGTCGGC
CACCAGGACGGGCTGAAGCCCGGGCGCACGGTGCGCGAGGAGCTGGTGTTCTGGAGCGTCTGGTCCGGGGGGACCGAGGC
CTCGGCGGCGGCCGCGGCCGAGACCTTCGACCTCGTCCGGCTGCTTGACCTCGAGGTCCGACGCCTGTCGGCGGGCCAGC
GGCGGCGCCTGGCCCTGTCGCGCACGGCCGCCGCGCCCCGGCCGCTCTGGCTGCTGGACGAGCCGCTCAGCCCGCTGGAC
GCCGGCTGGCGCGCGCGCGCGGGCGAGCTGATGGCCGGACACCTGGCCGACGGCGGGATGATCGTGGCCGCGGTGCACGA
CCCGCTGCCCATCCCCGCGGTCGCGCTGGATCTCGGCGCATGA

Upstream 100 bases:

>100_bases
CGCTTCATAGCCCCGGCCATCGCGCCCGTCCATGCGCGGCGCACCTTGCGAATCGTTCGCAAAATCTGAGGGGTAGCGCC
GCGGCGGGGCAGGCCGGCCG

Downstream 100 bases:

>100_bases
GCCGCTTCTCCGCCCTGCTCGCCCGCGAGACGGCCCTGGCCTGGGGCCGCGGCGGCGGCCCGCTGGTGGCAGTGGGCTTC
TACGCCGGCGTCGCCACCCT

Product: heme exporter protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MISELVISDASVRRGGRVLFEGLGLTLAAGQACALTGPNGSGKTSLLRAIAGLVRLEAGEIGFGGAEPAEARAAAVHFVG
HQDGLKPGRTVREELVFWSVWSGGTEASAAAAAETFDLVRLLDLEVRRLSAGQRRRLALSRTAAAPRPLWLLDEPLSPLD
AGWRARAGELMAGHLADGGMIVAAVHDPLPIPAVALDLGA

Sequences:

>Translated_200_residues
MISELVISDASVRRGGRVLFEGLGLTLAAGQACALTGPNGSGKTSLLRAIAGLVRLEAGEIGFGGAEPAEARAAAVHFVG
HQDGLKPGRTVREELVFWSVWSGGTEASAAAAAETFDLVRLLDLEVRRLSAGQRRRLALSRTAAAPRPLWLLDEPLSPLD
AGWRARAGELMAGHLADGGMIVAAVHDPLPIPAVALDLGA
>Mature_200_residues
MISELVISDASVRRGGRVLFEGLGLTLAAGQACALTGPNGSGKTSLLRAIAGLVRLEAGEIGFGGAEPAEARAAAVHFVG
HQDGLKPGRTVREELVFWSVWSGGTEASAAAAAETFDLVRLLDLEVRRLSAGQRRRLALSRTAAAPRPLWLLDEPLSPLD
AGWRARAGELMAGHLADGGMIVAAVHDPLPIPAVALDLGA

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=152, Percent_Identity=28.2894736842105, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI87082064, Length=182, Percent_Identity=38.4615384615385, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1790467, Length=182, Percent_Identity=32.4175824175824, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786563, Length=190, Percent_Identity=32.1052631578947, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1787370, Length=187, Percent_Identity=33.1550802139037, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788761, Length=172, Percent_Identity=35.4651162790698, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788225, Length=176, Percent_Identity=34.0909090909091, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790739, Length=192, Percent_Identity=30.7291666666667, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87081791, Length=170, Percent_Identity=32.3529411764706, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87081709, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=7e-14,
Organism=Escherichia coli, GI87082267, Length=159, Percent_Identity=32.7044025157233, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786803, Length=186, Percent_Identity=28.494623655914, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787182, Length=163, Percent_Identity=29.4478527607362, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787712, Length=175, Percent_Identity=30.2857142857143, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 20724; Mature: 20724

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISELVISDASVRRGGRVLFEGLGLTLAAGQACALTGPNGSGKTSLLRAIAGLVRLEAGE
CCCHHEECCCCCCCCCEEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
IGFGGAEPAEARAAAVHFVGHQDGLKPGRTVREELVFWSVWSGGTEASAAAAAETFDLVR
CCCCCCCCCHHHHEEEEEECCCCCCCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHH
LLDLEVRRLSAGQRRRLALSRTAAAPRPLWLLDEPLSPLDAGWRARAGELMAGHLADGGM
HHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCE
IVAAVHDPLPIPAVALDLGA
EEEEECCCCCCCEEEEECCC
>Mature Secondary Structure
MISELVISDASVRRGGRVLFEGLGLTLAAGQACALTGPNGSGKTSLLRAIAGLVRLEAGE
CCCHHEECCCCCCCCCEEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
IGFGGAEPAEARAAAVHFVGHQDGLKPGRTVREELVFWSVWSGGTEASAAAAAETFDLVR
CCCCCCCCCHHHHEEEEEECCCCCCCCCHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHH
LLDLEVRRLSAGQRRRLALSRTAAAPRPLWLLDEPLSPLDAGWRARAGELMAGHLADGGM
HHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCE
IVAAVHDPLPIPAVALDLGA
EEEEECCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]