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The map label for this gene is fhuG [H]

Identifier: 195978721

GI number: 195978721

Start: 1667931

End: 1668929

Strand: Direct

Name: fhuG [H]

Synonym: Sez_1621

Alternate gene names: 195978721

Gene position: 1667931-1668929 (Clockwise)

Preceding gene: 195978720

Following gene: 195978722

Centisome position: 82.4

GC content: 46.35

Gene sequence:

>999_bases
TTGACAGCTACTAAAAGACACGTCCCATTATTTCTAGGGCTAAGCGCTGGACTGGTCTGCTTGATGATCATTTCCTTATC
TATTGGGGATTCTAGCATGTCACCGTTAGAGGTTATCAAGGTTCTATTTGGAAAATCTACCGCCGCTATGACCTTGATCA
TCACCAACATTAGACTCCCAAGAATTTTAGCTGCCTGCATTGGTGGCGGATCACTGGCCCTTTCTGGCTTATTGCTGCAA
AGCTTAACGCGAAACCCTCTGGCAGATTCGGGCATATTAGGCATTAATGCTGGTGCTGGTATGGCTATTACCCTTGTCAT
ATCCTACAGCACCAGTGACAGCCTGATCAGCAGGCAATGGCTGTCGCTTATTACCATATTTGGGGCAATGGCAACCATTG
TCTTGGTCTACCTGCTCTCACTCAGTCATGGTCGTATCAATCCTATTCGACTGATTGTCACTGGCGTAGGGGTATCATCC
ATGCTATCTAGCCTGATGATTGCCTTTGTTGGCAATGTAAACCGTTACAAGGTGGATTACGTCATTCATTGGCTAAGCGG
GCAGCTAACAGGCGATGATTGGTCCAAGCTAAGCATTGTTGCTCCCTTATTGGGGATCACTTGGCTGCTTGCCTTTAGTC
AAGCCTATAAGCTCAACATCATGGCATTAAACGATGAAGCAAGCATGGCTCTAGGCTTCAAGCTCCATCAGTACCGTACA
ATTGTTCTTGCGCTATCTGCAATTCTCGCAGCTTTAAGTGTCATTTTGGTCGGAAACATCACCTTTATTGGCCTGATAGC
AGGACATACCAGCAAGCGACTAGTAGGAGCCGATCACCGATTAAGCCTGCCCGTTAGCCTTTTAATCGGCATGATCCTGC
TCCTTTTGGCCGACACTATCGGACGAGTCTATCTCGTCGGCAGCAATATTCCAACGGGAATTCTGGTCTCTATTCTTGGT
GCAGCTTATTTTCTCTACCTTATGGTAAAAATGAACTAA

Upstream 100 bases:

>100_bases
GTCGGAATATCAATCCCCCCTATGAAACACCGCTATCTGCTTTGATCAGCTTTATTGGGCTGCCCTGCTTTTTATGGCTA
GTTAGAAAAGGAGGTCGCTT

Downstream 100 bases:

>100_bases
AAGCCTTTACCACATAGCCTAACAAGCATAATGGCTTGGAACCTTTTTTCTACAATAGGGTTCTAAGCCATTTTTAGTTG
CAAGCATTACCATAAAAGCA

Product: ferrichrome transport system permease protein FhuG

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTATKRHVPLFLGLSAGLVCLMIISLSIGDSSMSPLEVIKVLFGKSTAAMTLIITNIRLPRILAACIGGGSLALSGLLLQ
SLTRNPLADSGILGINAGAGMAITLVISYSTSDSLISRQWLSLITIFGAMATIVLVYLLSLSHGRINPIRLIVTGVGVSS
MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKLNIMALNDEASMALGFKLHQYRT
IVLALSAILAALSVILVGNITFIGLIAGHTSKRLVGADHRLSLPVSLLIGMILLLLADTIGRVYLVGSNIPTGILVSILG
AAYFLYLMVKMN

Sequences:

>Translated_332_residues
MTATKRHVPLFLGLSAGLVCLMIISLSIGDSSMSPLEVIKVLFGKSTAAMTLIITNIRLPRILAACIGGGSLALSGLLLQ
SLTRNPLADSGILGINAGAGMAITLVISYSTSDSLISRQWLSLITIFGAMATIVLVYLLSLSHGRINPIRLIVTGVGVSS
MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKLNIMALNDEASMALGFKLHQYRT
IVLALSAILAALSVILVGNITFIGLIAGHTSKRLVGADHRLSLPVSLLIGMILLLLADTIGRVYLVGSNIPTGILVSILG
AAYFLYLMVKMN
>Mature_331_residues
TATKRHVPLFLGLSAGLVCLMIISLSIGDSSMSPLEVIKVLFGKSTAAMTLIITNIRLPRILAACIGGGSLALSGLLLQS
LTRNPLADSGILGINAGAGMAITLVISYSTSDSLISRQWLSLITIFGAMATIVLVYLLSLSHGRINPIRLIVTGVGVSSM
LSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKLNIMALNDEASMALGFKLHQYRTI
VLALSAILAALSVILVGNITFIGLIAGHTSKRLVGADHRLSLPVSLLIGMILLLLADTIGRVYLVGSNIPTGILVSILGA
AYFLYLMVKMN

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=284, Percent_Identity=34.1549295774648, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786805, Length=314, Percent_Identity=36.3057324840764, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788004, Length=307, Percent_Identity=31.9218241042345, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790741, Length=319, Percent_Identity=30.0940438871473, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786804, Length=322, Percent_Identity=28.2608695652174, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786347, Length=339, Percent_Identity=29.2035398230088, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35248; Mature: 35117

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATKRHVPLFLGLSAGLVCLMIISLSIGDSSMSPLEVIKVLFGKSTAAMTLIITNIRLP
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHEEEEEEECCCHH
RILAACIGGGSLALSGLLLQSLTRNPLADSGILGINAGAGMAITLVISYSTSDSLISRQW
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEEECCCHHHHHHHH
LSLITIFGAMATIVLVYLLSLSHGRINPIRLIVTGVGVSSMLSSLMIAFVGNVNRYKVDY
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEE
VIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKLNIMALNDEASMALGFKLHQYRT
EEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEHHHHHHH
IVLALSAILAALSVILVGNITFIGLIAGHTSKRLVGADHRLSLPVSLLIGMILLLLADTI
HHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHC
GRVYLVGSNIPTGILVSILGAAYFLYLMVKMN
CEEEEEECCCCHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
TATKRHVPLFLGLSAGLVCLMIISLSIGDSSMSPLEVIKVLFGKSTAAMTLIITNIRLP
CCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHEEEEEEECCCHH
RILAACIGGGSLALSGLLLQSLTRNPLADSGILGINAGAGMAITLVISYSTSDSLISRQW
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEEECCCHHHHHHHH
LSLITIFGAMATIVLVYLLSLSHGRINPIRLIVTGVGVSSMLSSLMIAFVGNVNRYKVDY
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEE
VIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKLNIMALNDEASMALGFKLHQYRT
EEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEHHHHHHH
IVLALSAILAALSVILVGNITFIGLIAGHTSKRLVGADHRLSLPVSLLIGMILLLLADTI
HHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHC
GRVYLVGSNIPTGILVSILGAAYFLYLMVKMN
CEEEEEECCCCHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]