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The map label for this gene is atpA [H]

Identifier: 195977925

GI number: 195977925

Start: 828873

End: 830378

Strand: Direct

Name: atpA [H]

Synonym: Sez_0796

Alternate gene names: 195977925

Gene position: 828873-830378 (Clockwise)

Preceding gene: 195977924

Following gene: 195977926

Centisome position: 40.95

GC content: 45.35

Gene sequence:

>1506_bases
TTGGCAATTAATGCACAAGAAATTAGCGCTTTAATTAAAAAGCAAATTGAGAACTTCCAGCCAAATTTCGATGTCACAGA
AACTGGAGTTGTTACCTATATTGGTGATGGGATTGCACGTGCTCGTGGCTTAGACAATGCGATGAGTGGTGAGCTTCTTG
AATTTTCAAATGGTACCTTCGGTATGGCTCAAAACCTAGAGTCAAACGATGTTGGTATCATTATTCTTGGTGATTTTTCA
ACGATTCGTGAGGGTGATGAAGTCAAACGTACCGGTAAAATTATGGAAGTGCCAGTCGGTGAAGCTCTCATTGGACGTGT
GGTCAATCCACTTGGTCAGCCTGTTGATGGCTTAGGTGACATTGAGACAACTGGCTTTAGGCCTGTTGAAACTCCAGCTC
CTGGTGTTATGCAGCGTAAGTCTGTTTTTGAGCCCTTACAAACCGGTCTAAAGGCTATTGATGCTTTGGTTCCGATTGGT
CGTGGCCAGCGCGAGCTGATTATCGGTGACCGTCAGACAGGTAAGACGTCTGTAGCCATTGATGCCATCTTGAATCAAAA
GGGGCAGGACATGATTTGTATCTATGTCGCTATTGGTCAAAAGGAATCAACAGTTCGGACACAGGTTGAAACCCTACGTC
GTTATGGTGCTTTGGATTATACCATTGTTGTAACGGCTTCTGCTTCACAGCCATCACCCTTGCTGTTTATTGCACCTTAT
GCTGGTGTTGCGATGGCAGAAGAGTTTATGTACAATGGCAAGCACGTTCTGATTGTTTATGATGACCTGTCTAAGCAGGC
GGTAGCTTATCGTGAATTGTCGCTCTTGCTTCGTCGCCCACCAGGTCGTGAGGCCTATCCAGGAGATGTTTTCTACCTGC
ATAGCCGCTTGCTTGAGCGCTCAGCTAAGGTGTCTGATGACTTAGGTGGTGGCTCAATTACAGCCTTACCATTTATTGAG
ACGCAGGCTGGGGATATCTCTGCCTACATTGCGACAAACGTGATTTCGATTACAGATGGTCAGATTTTCTTGCAAGAGGA
TCTCTTTAACTCAGGAATCCGCCCAGCCATTGATGCTGGCTCGTCAGTATCTCGTGTCGGTGGCTCTGCACAGATCAAGG
CTATGAAAAGGGTTGCAGGGACTTTGCGTCTTGACCTGGCCTCTTATCGTGAGTTAGAAGCCTTTACACAATTTGGTTCA
GATCTAGATGCAGCAACGCAAGCAAAATTAAATCGTGGTCGTCGTACCGTTGAAATTCTAAAGCAGCCATTGCACAAGCC
CTTGCCTGTTGAAAAGCAGGTGGTCATTTTGTACGCCTTGACGCATGGATTTTTAGATGATGTTCCTGTAGATGATATTT
TAGCCTTTGAAGAAGCCCTTTATGACTACTTTGATGCGCATTATGATCACTTATTTGAAACAATCCGTACAACCAAAGAC
CTTCCGCAGGAGGCTGAGCTGGACGCTGCTATCCAAGCCTTCAAAGCACAGTCAAACTTTAAATAA

Upstream 100 bases:

>100_bases
AGGATTTATGATTAGCGTCAATAATAAGGTAATTGATACAAGCATTCGTCGTCAATTACAAGCATTTAAAATGAATTTAA
AATAGAAAGTGGTGTGACTT

Downstream 100 bases:

>100_bases
AAGAGGGGGTACTAGTATGGCAGGCTCTCTAAGTGAAATTAAGGCTAAAATCATTTCAACCGAAAAAACAAGCAAAATCA
CTAGCGCCATGCGTATGGTT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGLDNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFS
TIREGDEVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPY
AGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIE
TQAGDISAYIATNVISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYRELEAFTQFGS
DLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDAHYDHLFETIRTTKD
LPQEAELDAAIQAFKAQSNFK

Sequences:

>Translated_501_residues
MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGLDNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFS
TIREGDEVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPY
AGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIE
TQAGDISAYIATNVISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYRELEAFTQFGS
DLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDAHYDHLFETIRTTKD
LPQEAELDAAIQAFKAQSNFK
>Mature_500_residues
AINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGLDNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFST
IREGDEVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFEPLQTGLKAIDALVPIGR
GQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPYA
GVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIET
QAGDISAYIATNVISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYRELEAFTQFGSD
LDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDAHYDHLFETIRTTKDL
PQEAELDAAIQAFKAQSNFK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=488, Percent_Identity=58.1967213114754, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI4757810, Length=488, Percent_Identity=58.1967213114754, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI19913426, Length=301, Percent_Identity=29.2358803986711, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913428, Length=301, Percent_Identity=29.2358803986711, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI32189394, Length=427, Percent_Identity=25.5269320843091, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=52.2417153996101, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=34.9264705882353, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1790170, Length=384, Percent_Identity=26.3020833333333, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=503, Percent_Identity=57.2564612326044, Blast_Score=564, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71988080, Length=503, Percent_Identity=57.2564612326044, Blast_Score=562, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988074, Length=503, Percent_Identity=53.0815109343936, Blast_Score=506, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17510931, Length=366, Percent_Identity=27.8688524590164, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=299, Percent_Identity=29.0969899665552, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=429, Percent_Identity=23.3100233100233, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=500, Percent_Identity=56.2, Blast_Score=560, Evalue=1e-160,
Organism=Saccharomyces cerevisiae, GI6319603, Length=304, Percent_Identity=28.9473684210526, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=409, Percent_Identity=24.4498777506112, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24658560, Length=477, Percent_Identity=58.7002096436059, Blast_Score=553, Evalue=1e-157,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=28.9036544850498, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=28.9036544850498, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=28.9036544850498, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28574560, Length=427, Percent_Identity=25.0585480093677, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24638766, Length=409, Percent_Identity=24.6943765281174, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54677; Mature: 54546

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGLDNAMSGELLEFSNGTF
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHCCCCCHHCCCEEEECCCCC
GMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGD
HHHCCCCCCCEEEEEECCCHHHCCCHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
IETTGFRPVETPAPGVMQRKSVFEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCC
AGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQEDLFNSGIRPAIDAG
HHHCCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCEEEEEHHHHCCCCCCHHCCC
SSVSRVGGSAQIKAMKRVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEIL
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
KQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDAHYDHLFETIRTTKD
HHHCCCCCCCCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPQEAELDAAIQAFKAQSNFK
CCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGLDNAMSGELLEFSNGTF
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHCCCCCHHCCCEEEECCCCC
GMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGD
HHHCCCCCCCEEEEEECCCHHHCCCHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
IETTGFRPVETPAPGVMQRKSVFEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCC
AGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQEDLFNSGIRPAIDAG
HHHCCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCEEEEEHHHHCCCCCCHHCCC
SSVSRVGGSAQIKAMKRVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEIL
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
KQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDAHYDHLFETIRTTKD
HHHCCCCCCCCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPQEAELDAAIQAFKAQSNFK
CCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]