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The map label for this gene is prsA [H]

Identifier: 195977800

GI number: 195977800

Start: 688377

End: 689378

Strand: Direct

Name: prsA [H]

Synonym: Sez_0666

Alternate gene names: 195977800

Gene position: 688377-689378 (Clockwise)

Preceding gene: 195977799

Following gene: 195977801

Centisome position: 34.01

GC content: 38.62

Gene sequence:

>1002_bases
ATGAAAAAATCAACTAAATTACTTGCTGGTATAGTAACCCTAGCATCAGCAATGACCCTAGCAGCCTGTCAGTCTACAAA
TGACAACACAAGTGTCATTACGATGAAGGGCGACACTATCAGTGTTAGTGATTTTTACAACGAAACAAAAAATACAGAGA
TTTCTCAAAGAGCAATGCTAAACCTTGTGGTTAGTCGTGTTTTTGAGGACCAATACGGTAAAAAGGTTTCTAAGAAAAAA
ACAGAAGAAGCCTACAATAAATCAGCTGAGCAATACGGTGCGTCATTCTCTGCAGCCCTTGCGCAGTCTGGCTTGACAAC
AGATACCTACAAGCGTCAAATTCGCTCAGCTATGCTGGTTGAATATGCTGTTAAAGAAGCAGCTAAAAAAGAGCTGACAG
ATGCTGATTACAAAAAAGCCTATGAGTCATACACACCAGAAATGACTACTCAGGTCATTACTCTAGACAATGAAGAAACA
GCTAAGGCTATTTTAGGTGAGGTTAAGGCTGAGGGTGCTGACTTTGCTGCTATTGCTAAGGAAAAGACAACAGCAGCAGA
CAAGAAGGTAGACTATAAGTTTGATTCAGGAGATACTAAGTTACCAGCAGATGTGATCAAAGCCGCTTCAGGATTAAAAG
AGGGTGATATTTCAGAGGTGGTTTCAGTTCTAGATCCAGCGACCTACCAAAACAAATTCTATATTGTTAAGGTAACCAAA
AAAGCTGAAAAGGCTTCTGATTGGAAGAAATATAAGAAACGTTTGAAAGAAATTGTCTTGGCTGAAAAGACACAAAACAT
TGATTTCCAAAACAAGGTCATTGCAAAGGCTTTAGATAAAGCAAATGTTAAGATCAAAGACCAAGCCTTTGCTAATATCT
TGGCACAGTATGCCAATACTGATAAAAAAGCAAGCAAGGCGAACACAAGCAAGTCAGATCAAAAAACATCTTCAGACTCA
AGCAAGGACAGTCAATCTTCCAAATCTAAATCAGAAAAATAG

Upstream 100 bases:

>100_bases
TTCGTAAAAATCAAGCAGATATTCGTTTGTTAGATTAAGTTACGTTTAAGAAATTGTGATATAATATACTGGTTAATGAC
AAAAAGGAGCACAAAATCAC

Downstream 100 bases:

>100_bases
ATTTTCATTGACGAATGGGCAAAAAAGCTTTATACTGGTTTAGTTAAGAATTGTTTATCAAGGATTTGACCCAGAGAAGT
GACGGTTGCTGTGAGTTACG

Product: foldase protein PrsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSDFYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKK
TEEAYNKSAEQYGASFSAALAQSGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVITLDNEET
AKAILGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDISEVVSVLDPATYQNKFYIVKVTK
KAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAKALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKTSSDS
SKDSQSSKSKSEK

Sequences:

>Translated_333_residues
MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSDFYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKK
TEEAYNKSAEQYGASFSAALAQSGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVITLDNEET
AKAILGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDISEVVSVLDPATYQNKFYIVKVTK
KAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAKALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKTSSDS
SKDSQSSKSKSEK
>Mature_333_residues
MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSDFYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKK
TEEAYNKSAEQYGASFSAALAQSGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVITLDNEET
AKAILGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDISEVVSVLDPATYQNKFYIVKVTK
KAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAKALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKTSSDS
SKDSQSSKSKSEK

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 36575; Mature: 36575

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSDFYNETKNTEISQRAML
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHCCCHHHHHHHH
NLVVSRVFEDQYGKKVSKKKTEEAYNKSAEQYGASFSAALAQSGLTTDTYKRQIRSAMLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHH
EYAVKEAAKKELTDADYKKAYESYTPEMTTQVITLDNEETAKAILGEVKAEGADFAAIAK
HHHHHHHHHHHCCCHHHHHHHHHCCCCHHEEEEEECCHHHHHHHHHHHHCCCCCHHHHHH
EKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDISEVVSVLDPATYQNKFYIVKVTK
HHHHHHCCCCCEEECCCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCHHCCCEEEEEECC
KAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAKALDKANVKIKDQAFANILAQYANT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCC
DKKASKANTSKSDQKTSSDSSKDSQSSKSKSEK
CHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSDFYNETKNTEISQRAML
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHCCCHHHHHHHH
NLVVSRVFEDQYGKKVSKKKTEEAYNKSAEQYGASFSAALAQSGLTTDTYKRQIRSAMLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHH
EYAVKEAAKKELTDADYKKAYESYTPEMTTQVITLDNEETAKAILGEVKAEGADFAAIAK
HHHHHHHHHHHCCCHHHHHHHHHCCCCHHEEEEEECCHHHHHHHHHHHHCCCCCHHHHHH
EKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDISEVVSVLDPATYQNKFYIVKVTK
HHHHHHCCCCCEEECCCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCHHCCCEEEEEECC
KAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAKALDKANVKIKDQAFANILAQYANT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCC
DKKASKANTSKSDQKTSSDSSKDSQSSKSKSEK
CHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA