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The map label for this gene is arcB [H]

Identifier: 195977708

GI number: 195977708

Start: 595742

End: 596755

Strand: Direct

Name: arcB [H]

Synonym: Sez_0570

Alternate gene names: 195977708

Gene position: 595742-596755 (Clockwise)

Preceding gene: 195977707

Following gene: 195977709

Centisome position: 29.43

GC content: 42.41

Gene sequence:

>1014_bases
ATGACACAAGTATTTCAAGGACGTAGCTTCTTAGCAGAAAAAGACTTTACACGTGAGGAATTTGAATACCTCATTGATTT
TGCAGCACACTTGAAAGACCTTAAAAAGCGTGGTATTCCACATCACTATTTAGAAGGTAAAAATATTGCTCTTTTATTTG
AAAAAACATCAACTCGTACACGTGCTGCCTTTACAACTGCAGCAATTGATTTAGGAGCTCATCCTGAATACCTTGGTGCT
AACGATATTCAGCTTGGTAAAAAGGAATCAACAGAGGACACAGCTAAGGTATTGGGTCGTATGTTTGATGGGATTGAATT
CCGTGGCTTTAGCCAACGTATGGTTGAAGAATTGGCAGAATTCTCAGGTGTTCCAGTGTGGAATGGCTTGACTGATGAAT
GGCACCCAACCCAAATGCTTGCGGACTACCTTACTGTCAAGGAAAACTTTGGTAAGCTTGAAGGCTTGACCTTGGTTTAC
TGTGGTGATGGACGCAACAACGTTGCCAATTCACTGTTAGTAGCAGGTACCTTACTAGGTGTGAATGTTCATATCTTCTC
ACCAAAAGAGCTCTTCCCAGCAGAAGACATCGTGAAGCTGGCTGAGGGCTATGCTAAAGCATCAGGTGCGCATGTGTTAG
TTACTGACAATGCTGATGAGGCTGTTAAGGGTGCAGATGTGCTTTACACTGATGTGTGGGTGTCAATGGGTGAAGAAGAC
AAGTTTGAAGAGCGTGTGAAGCTCTTGAAGCCATATCAAGTGAACATGGAGCTTGTTAAAAAAGCAGACAACGACAACCT
TATCTTCTTACATTGCTTGCCAGCCTTCCATGACACAAATACTGTTTACGGAAAAGACGTTGCTGAGAAATTTGGTGTAG
AAGAAATGGAAGTAACAGATGAGGTCTTCCGCAGCAAATACGCTCGCCACTTTGACCAAGCAGAAAACCGTATGCACACT
ATTAAAGCGGTTATGGCCGCAACTCTTGGTAATCTTTTCATTCCAAAAGTGTAA

Upstream 100 bases:

>100_bases
TTTATGAAGGTCTTGGCTATCAAGCCTTTGGCGAGCCTTATGATGAAGACGGTGAGCCTTGTCAATCAGTAGAAAAATAT
TTATAAAAAGGAGAATTTAA

Downstream 100 bases:

>100_bases
GCTGTGATTGGTACCTTTTAATTTATTTTAGCTCATTTCATTAATTTAACATTTAACTACTAAAAAACGTACTTTAACTA
CATGACGAGTCGTTCTGGTT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase 2 [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGA
NDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNADEAVKGADVLYTDVWVSMGEED
KFEERVKLLKPYQVNMELVKKADNDNLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHT
IKAVMAATLGNLFIPKV

Sequences:

>Translated_337_residues
MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGA
NDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNADEAVKGADVLYTDVWVSMGEED
KFEERVKLLKPYQVNMELVKKADNDNLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHT
IKAVMAATLGNLFIPKV
>Mature_336_residues
TQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGAN
DIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYC
GDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNADEAVKGADVLYTDVWVSMGEEDK
FEERVKLLKPYQVNMELVKKADNDNLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTI
KAVMAATLGNLFIPKV

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=326, Percent_Identity=40.4907975460123, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI18105007, Length=332, Percent_Identity=23.4939759036145, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786469, Length=327, Percent_Identity=53.5168195718654, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1790703, Length=329, Percent_Identity=52.5835866261398, Blast_Score=337, Evalue=5e-94,
Organism=Escherichia coli, GI48994908, Length=377, Percent_Identity=25.7294429708223, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367364, Length=343, Percent_Identity=26.8221574344023, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193204318, Length=268, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=335, Percent_Identity=35.8208955223881, Blast_Score=180, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6322331, Length=331, Percent_Identity=26.5861027190332, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24642586, Length=329, Percent_Identity=27.0516717325228, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37881; Mature: 37750

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYLEGKNIALLFEKTSTRT
CCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCH
RAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAE
HHHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVAGTLLG
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHEEE
VNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNADEAVKGADVLYTDVWVSMGEED
EEEEEECCHHHCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCEEEEHHHHHCCCCC
KFEERVKLLKPYQVNMELVKKADNDNLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTD
HHHHHHHHHCCHHCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCCHHHHHH
EVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYLEGKNIALLFEKTSTRT
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCH
RAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAE
HHHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVAGTLLG
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHEEE
VNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNADEAVKGADVLYTDVWVSMGEED
EEEEEECCHHHCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCEEEEHHHHHCCCCC
KFEERVKLLKPYQVNMELVKKADNDNLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTD
HHHHHHHHHCCHHCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCCHHHHHH
EVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12354221 [H]