| Definition | Streptococcus equi subsp. zooepidemicus MGCS10565, complete genome. |
|---|---|
| Accession | NC_011134 |
| Length | 2,024,171 |
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The map label for this gene is yvgN [H]
Identifier: 195977619
GI number: 195977619
Start: 499418
End: 500257
Strand: Direct
Name: yvgN [H]
Synonym: Sez_0478
Alternate gene names: 195977619
Gene position: 499418-500257 (Clockwise)
Preceding gene: 195977618
Following gene: 195977620
Centisome position: 24.67
GC content: 47.62
Gene sequence:
>840_bases ATGATTAAAACAGTAACAATGGCTAATGGTCTTGCTATTCCAGTGCTTGGCTTTGGGACCTTTAAGGCTGCTGATGGTGA GGAGGCCTACCAATCCACCCTAGCAGCGATTAAGGCAGGCTATCGTCATATTGACACAGCTGCCATTTATCACAATGAAA AAAGTGTTGGACAGGCCATTCGGGATTCGGGCGTTCCTCGTGAAGAGCTCTTTATTACCACTAAGCTCTGGAATGACGCT CATAGCTATGATGGCGCTAAGGCAGCCTTAGCAGATTCTCTTGAACGTCTTGGACTAGAGTATGTAGACCTTTATCTGAT TCACTGGCCAAATCCTAAGGCTCTTAGGGATTGCTGGCAAGCAGCCAATGCAGCAGCTTGGTCTTATATGGAGGAGGCTG TTGAAGCGGGCTTGGTCCGCTCGATTGGTGTCAGCAACTTTATGGTTCACCATCTGGAGGCTCTACAAAAGACAGCCACC ATTACACCAGCAGTCAATCAGATTCGCTTGGCGCCTGGCTGCTATCAAAAAGAGACGGTTGATTATTGCCGCAGGCATCA CATTTTGCTAGAGGCCTGGAGTCCGCTAGGACAAGGAGAGATATTTACCGATGATACCATGCAGGCATTGGCTAAAAAGT ACAACAAGACAGTGGCTCAGCTAGCCCTTGCTTGGTCTATTGCTGAGGGCTTTATTCCTCTACCTAAGTCGGTGCACAAG GAACGCATAGTAGAAAATATGGCTATTTTTGATTGTGAGATTAGTCCAGAGGATTCAGAGCGCATTCGTTGCCTGCCGGG TATGTCAGCTATCCCAGATCCTGATACCAAGGACTTTTAG
Upstream 100 bases:
>100_bases CCTTTGAGGCTTGATACGGTAAAGGAATTGGGCTAGTGATCAGCTCAATTCTTTTTGCTTTGCTTATCATTGTGCTACAA TAAAAAAGGAGGTTTTAGAT
Downstream 100 bases:
>100_bases CAAGAGCTGCAGGGACTAAGTGGGTTGCCTTAGTAGCTCTTGCTTATTGTTTTATCGATTAATAATTGTCTAATTTTTAT AATGTGAATTAAATCACTTG
Product: 2,5-diketo-D-gluconic acid reductase
Products: NA
Alternate protein names: GR; Methylglyoxal reductase [H]
Number of amino acids: Translated: 279; Mature: 279
Protein sequence:
>279_residues MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHIDTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDA HSYDGAKAALADSLERLGLEYVDLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALQKTAT ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWSPLGQGEIFTDDTMQALAKKYNKTVAQLALAWSIAEGFIPLPKSVHK ERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDTKDF
Sequences:
>Translated_279_residues MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHIDTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDA HSYDGAKAALADSLERLGLEYVDLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALQKTAT ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWSPLGQGEIFTDDTMQALAKKYNKTVAQLALAWSIAEGFIPLPKSVHK ERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDTKDF >Mature_279_residues MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHIDTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDA HSYDGAKAALADSLERLGLEYVDLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALQKTAT ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWSPLGQGEIFTDDTMQALAKKYNKTVAQLALAWSIAEGFIPLPKSVHK ERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDTKDF
Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=288, Percent_Identity=34.375, Blast_Score=179, Evalue=2e-45, Organism=Homo sapiens, GI5174391, Length=288, Percent_Identity=34.375, Blast_Score=179, Evalue=2e-45, Organism=Homo sapiens, GI310109920, Length=300, Percent_Identity=36, Blast_Score=178, Evalue=5e-45, Organism=Homo sapiens, GI5453543, Length=300, Percent_Identity=35.6666666666667, Blast_Score=176, Evalue=1e-44, Organism=Homo sapiens, GI45446745, Length=300, Percent_Identity=35.3333333333333, Blast_Score=174, Evalue=8e-44, Organism=Homo sapiens, GI4503285, Length=300, Percent_Identity=35.3333333333333, Blast_Score=174, Evalue=8e-44, Organism=Homo sapiens, GI310109922, Length=286, Percent_Identity=35.6643356643357, Blast_Score=174, Evalue=1e-43, Organism=Homo sapiens, GI24497585, Length=300, Percent_Identity=35.3333333333333, Blast_Score=170, Evalue=1e-42, Organism=Homo sapiens, GI24497583, Length=293, Percent_Identity=35.1535836177474, Blast_Score=169, Evalue=2e-42, Organism=Homo sapiens, GI5174695, Length=293, Percent_Identity=34.8122866894198, Blast_Score=169, Evalue=3e-42, Organism=Homo sapiens, GI223468663, Length=290, Percent_Identity=34.8275862068965, Blast_Score=165, Evalue=4e-41, Organism=Homo sapiens, GI4502049, Length=286, Percent_Identity=37.4125874125874, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI300116273, Length=277, Percent_Identity=34.6570397111913, Blast_Score=160, Evalue=2e-39, Organism=Homo sapiens, GI93277124, Length=294, Percent_Identity=32.6530612244898, Blast_Score=154, Evalue=8e-38, Organism=Homo sapiens, GI291291012, Length=256, Percent_Identity=33.59375, Blast_Score=140, Evalue=1e-33, Organism=Homo sapiens, GI300116271, Length=280, Percent_Identity=31.0714285714286, Blast_Score=130, Evalue=9e-31, Organism=Homo sapiens, GI310109926, Length=114, Percent_Identity=47.3684210526316, Blast_Score=106, Evalue=3e-23, Organism=Homo sapiens, GI207028673, Length=114, Percent_Identity=45.6140350877193, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI310109924, Length=146, Percent_Identity=32.1917808219178, Blast_Score=82, Evalue=7e-16, Organism=Escherichia coli, GI87082198, Length=275, Percent_Identity=41.4545454545455, Blast_Score=212, Evalue=2e-56, Organism=Escherichia coli, GI1786400, Length=259, Percent_Identity=37.8378378378378, Blast_Score=178, Evalue=3e-46, Organism=Escherichia coli, GI1788081, Length=273, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1788070, Length=309, Percent_Identity=23.6245954692557, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI48994888, Length=216, Percent_Identity=28.2407407407407, Blast_Score=66, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71998625, Length=259, Percent_Identity=37.8378378378378, Blast_Score=176, Evalue=2e-44, Organism=Caenorhabditis elegans, GI17561298, Length=269, Percent_Identity=34.9442379182156, Blast_Score=169, Evalue=2e-42, Organism=Caenorhabditis elegans, GI17537075, Length=305, Percent_Identity=33.7704918032787, Blast_Score=168, Evalue=2e-42, Organism=Caenorhabditis elegans, GI17537077, Length=305, Percent_Identity=34.0983606557377, Blast_Score=168, Evalue=3e-42, Organism=Caenorhabditis elegans, GI17552492, Length=263, Percent_Identity=33.4600760456274, Blast_Score=163, Evalue=1e-40, Organism=Caenorhabditis elegans, GI17538386, Length=271, Percent_Identity=34.3173431734317, Blast_Score=157, Evalue=4e-39, Organism=Caenorhabditis elegans, GI17537079, Length=294, Percent_Identity=31.6326530612245, Blast_Score=154, Evalue=6e-38, Organism=Caenorhabditis elegans, GI17550248, Length=287, Percent_Identity=34.4947735191638, Blast_Score=151, Evalue=3e-37, Organism=Caenorhabditis elegans, GI17564128, Length=295, Percent_Identity=30.8474576271186, Blast_Score=150, Evalue=9e-37, Organism=Caenorhabditis elegans, GI17566692, Length=277, Percent_Identity=34.2960288808664, Blast_Score=147, Evalue=4e-36, Organism=Caenorhabditis elegans, GI17561300, Length=254, Percent_Identity=31.1023622047244, Blast_Score=138, Evalue=4e-33, Organism=Caenorhabditis elegans, GI17562292, Length=279, Percent_Identity=29.7491039426523, Blast_Score=135, Evalue=2e-32, Organism=Saccharomyces cerevisiae, GI6320576, Length=279, Percent_Identity=42.2939068100358, Blast_Score=214, Evalue=1e-56, Organism=Saccharomyces cerevisiae, GI6324694, Length=287, Percent_Identity=39.3728222996516, Blast_Score=206, Evalue=3e-54, Organism=Saccharomyces cerevisiae, GI6322556, Length=265, Percent_Identity=37.3584905660377, Blast_Score=173, Evalue=3e-44, Organism=Saccharomyces cerevisiae, GI6319625, Length=269, Percent_Identity=39.0334572490706, Blast_Score=158, Evalue=1e-39, Organism=Saccharomyces cerevisiae, GI6321896, Length=290, Percent_Identity=31.7241379310345, Blast_Score=144, Evalue=2e-35, Organism=Saccharomyces cerevisiae, GI6320079, Length=282, Percent_Identity=32.6241134751773, Blast_Score=138, Evalue=8e-34, Organism=Drosophila melanogaster, GI20129731, Length=275, Percent_Identity=40, Blast_Score=193, Evalue=1e-49, Organism=Drosophila melanogaster, GI24657054, Length=275, Percent_Identity=40.3636363636364, Blast_Score=187, Evalue=4e-48, Organism=Drosophila melanogaster, GI24663317, Length=280, Percent_Identity=37.1428571428571, Blast_Score=187, Evalue=5e-48, Organism=Drosophila melanogaster, GI21356425, Length=282, Percent_Identity=37.9432624113475, Blast_Score=179, Evalue=2e-45, Organism=Drosophila melanogaster, GI45553081, Length=285, Percent_Identity=35.7894736842105, Blast_Score=171, Evalue=4e-43, Organism=Drosophila melanogaster, GI24644950, Length=297, Percent_Identity=36.7003367003367, Blast_Score=170, Evalue=8e-43, Organism=Drosophila melanogaster, GI24662785, Length=278, Percent_Identity=38.8489208633094, Blast_Score=164, Evalue=8e-41, Organism=Drosophila melanogaster, GI221378297, Length=317, Percent_Identity=34.384858044164, Blast_Score=163, Evalue=1e-40, Organism=Drosophila melanogaster, GI24662789, Length=288, Percent_Identity=36.1111111111111, Blast_Score=162, Evalue=2e-40, Organism=Drosophila melanogaster, GI24662781, Length=281, Percent_Identity=37.7224199288256, Blast_Score=162, Evalue=2e-40, Organism=Drosophila melanogaster, GI281366140, Length=248, Percent_Identity=36.2903225806452, Blast_Score=154, Evalue=5e-38,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.283 [H]
Molecular weight: Translated: 30922; Mature: 30922
Theoretical pI: Translated: 5.58; Mature: 5.58
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHIDTAAIYHNEKSVGQAI CCEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHH RDSGVPREELFITTKLWNDAHSYDGAKAALADSLERLGLEYVDLYLIHWPNPKALRDCWQ HHCCCCHHHEEEEEHHHCCHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHH AANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALQKTATITPAVNQIRLAPGCYQKETV HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHH DYCRRHHILLEAWSPLGQGEIFTDDTMQALAKKYNKTVAQLALAWSIAEGFIPLPKSVHK HHHHHHHHHEECCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH ERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDTKDF HHHHHHHHEEEEECCCCCCCCEEECCCCCCCCCCCCCCC >Mature Secondary Structure MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHIDTAAIYHNEKSVGQAI CCEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHH RDSGVPREELFITTKLWNDAHSYDGAKAALADSLERLGLEYVDLYLIHWPNPKALRDCWQ HHCCCCHHHEEEEEHHHCCHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHH AANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALQKTATITPAVNQIRLAPGCYQKETV HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHH DYCRRHHILLEAWSPLGQGEIFTDDTMQALAKKYNKTVAQLALAWSIAEGFIPLPKSVHK HHHHHHHHHEECCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH ERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDTKDF HHHHHHHHEEEEECCCCCCCCEEECCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9639930; 9384377 [H]