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The map label for this gene is lacB [H]

Identifier: 195977595

GI number: 195977595

Start: 477303

End: 477818

Strand: Direct

Name: lacB [H]

Synonym: Sez_0454

Alternate gene names: 195977595

Gene position: 477303-477818 (Clockwise)

Preceding gene: 195977594

Following gene: 195977596

Centisome position: 23.58

GC content: 43.02

Gene sequence:

>516_bases
ATGAAAATTGCTATTGGCTGTGACCATATTGTGACGAATGAAAAAATGGCTGTTTCAGATTTTTTGAAATCAAAGGGCTA
TGAGGTGATTGACTGTGGGACCTATGACCATACCCGCACCCATTACCCGATTTTTGGGAAAAGGGTTGGTGAGGCTGTCG
CTAATGGCCGAGCTGATCTTGGTGTCTGTATCTGTGGCACTGGTGTGGGGATTAATAATGCTGTCAACAAGGTTTCTGGC
ATTCGCTCAGCGCTTGTTAGGGATATGACGACAGCACTGTATGCAAAAGAGGAGCTCAATGCAAATGTCATAGGCTTTGG
CGGTAAAATCACAGGCGAGCTTTTAATGTGTGATATTATTGATGCTTTTATCAAGGCAGATTATAGGGAAACTGATGACA
ATAAAAAGCTGCTTGCTAAAATAGCTCATTTAGAGACACAGCACGTCAATCAAGAGGATCCTGACTTTTTCAACGAATTT
CTGGACAAATGGGATCGCGGTGACTACCAGGATTAG

Upstream 100 bases:

>100_bases
AAACATTGCTAAGGCTTTTGTGGTCGGCAGCTACGATGGCGGACGCCATCAAATACGTGTAGACATGCTCAATAAAATGG
CTTAACGAAGGGAAGATATC

Downstream 100 bases:

>100_bases
GAGAGCATATGATTTTAACAGTAACCTTAAATCCTTCTATTGATATTTCCTATCCTTTGGAGGCCTTAGCCTTGGATCGG
GTAAACCGCGTGGAAGCGGT

Product: galactose-6-phosphate isomerase subunit LacB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKIAIGCDHIVTNEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPIFGKRVGEAVANGRADLGVCICGTGVGINNAVNKVSG
IRSALVRDMTTALYAKEELNANVIGFGGKITGELLMCDIIDAFIKADYRETDDNKKLLAKIAHLETQHVNQEDPDFFNEF
LDKWDRGDYQD

Sequences:

>Translated_171_residues
MKIAIGCDHIVTNEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPIFGKRVGEAVANGRADLGVCICGTGVGINNAVNKVSG
IRSALVRDMTTALYAKEELNANVIGFGGKITGELLMCDIIDAFIKADYRETDDNKKLLAKIAHLETQHVNQEDPDFFNEF
LDKWDRGDYQD
>Mature_171_residues
MKIAIGCDHIVTNEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPIFGKRVGEAVANGRADLGVCICGTGVGINNAVNKVSG
IRSALVRDMTTALYAKEELNANVIGFGGKITGELLMCDIIDAFIKADYRETDDNKKLLAKIAHLETQHVNQEDPDFFNEF
LDKWDRGDYQD

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=141, Percent_Identity=39.0070921985816, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004784
- InterPro:   IPR003500 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: =5.3.1.26 [H]

Molecular weight: Translated: 18953; Mature: 18953

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIGCDHIVTNEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPIFGKRVGEAVANGRADL
CEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
GVCICGTGVGINNAVNKVSGIRSALVRDMTTALYAKEELNANVIGFGGKITGELLMCDII
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
DAFIKADYRETDDNKKLLAKIAHLETQHVNQEDPDFFNEFLDKWDRGDYQD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIAIGCDHIVTNEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPIFGKRVGEAVANGRADL
CEEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
GVCICGTGVGINNAVNKVSGIRSALVRDMTTALYAKEELNANVIGFGGKITGELLMCDII
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
DAFIKADYRETDDNKKLLAKIAHLETQHVNQEDPDFFNEFLDKWDRGDYQD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]