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The map label for this gene is lacA

Identifier: 195977594

GI number: 195977594

Start: 476862

End: 477287

Strand: Direct

Name: lacA

Synonym: Sez_0453

Alternate gene names: 195977594

Gene position: 476862-477287 (Clockwise)

Preceding gene: 195977592

Following gene: 195977595

Centisome position: 23.56

GC content: 44.84

Gene sequence:

>426_bases
ATGGCTATTATTTTGGGTGCAGATGCACATGGCAATGAGTTAAAAGAGGTTCTTAAAAGCTTTCTTCAGCAGGAAGGCTT
TGATGTGACAGACGTGACAGACATAGATAAGGATTTTATTGACAATACCTTGGCAGTTGCTCAGGCGGTCAATGATAAGG
ACACTAATCTTGGTATTATGGTCGATGCTTATGGTGCAGGCCCATTTATGGTGGCGACCAAGCTAAAAGGCATGATAGCA
GCAGAGGTTTCTGATGAGCGCTCTGCCTACATGACACGTGGCCACAATAATGCTCGTATGATTACCCTTGGTGCAAGGAT
TGTTGGTGAGGAGCTGGCAAAAAACATTGCTAAGGCTTTTGTGGTCGGCAGCTACGATGGCGGACGCCATCAAATACGTG
TAGACATGCTCAATAAAATGGCTTAA

Upstream 100 bases:

>100_bases
AAAATATATGTTGATAAATGTTTGTTTTTAATATAAAATAATCTTGTAAACGATTAACAAACAATATCGAACAAAATTAA
TCAAATGTAAAGGAGATGTG

Downstream 100 bases:

>100_bases
CGAAGGGAAGATATCATGAAAATTGCTATTGGCTGTGACCATATTGTGACGAATGAAAAAATGGCTGTTTCAGATTTTTT
GAAATCAAAGGGCTATGAGG

Product: galactose-6-phosphate isomerase subunit LacA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MAIILGADAHGNELKEVLKSFLQQEGFDVTDVTDIDKDFIDNTLAVAQAVNDKDTNLGIMVDAYGAGPFMVATKLKGMIA
AEVSDERSAYMTRGHNNARMITLGARIVGEELAKNIAKAFVVGSYDGGRHQIRVDMLNKMA

Sequences:

>Translated_141_residues
MAIILGADAHGNELKEVLKSFLQQEGFDVTDVTDIDKDFIDNTLAVAQAVNDKDTNLGIMVDAYGAGPFMVATKLKGMIA
AEVSDERSAYMTRGHNNARMITLGARIVGEELAKNIAKAFVVGSYDGGRHQIRVDMLNKMA
>Mature_140_residues
AIILGADAHGNELKEVLKSFLQQEGFDVTDVTDIDKDFIDNTLAVAQAVNDKDTNLGIMVDAYGAGPFMVATKLKGMIAA
EVSDERSAYMTRGHNNARMITLGARIVGEELAKNIAKAFVVGSYDGGRHQIRVDMLNKMA

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family

Homologues:

Organism=Escherichia coli, GI1790528, Length=141, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACA_STREM (B4U1F8)

Other databases:

- EMBL:   CP001129
- RefSeq:   YP_002122838.1
- ProteinModelPortal:   B4U1F8
- EnsemblBacteria:   EBSTRT00000010063
- GeneID:   6761368
- GenomeReviews:   CP001129_GR
- KEGG:   sez:Sez_0453
- GeneTree:   EBGT00050000027285
- HOGENOM:   HBG636953
- OMA:   SAMASNK
- ProtClustDB:   PRK12613
- HAMAP:   MF_01555
- InterPro:   IPR004783
- InterPro:   IPR003500
- Gene3D:   G3DSA:3.40.1400.10
- PIRSF:   PIRSF005384
- TIGRFAMs:   TIGR01118
- TIGRFAMs:   TIGR00689

Pfam domain/function: PF02502 LacAB_rpiB; SSF89623 Rib/Gal_isomrase

EC number: =5.3.1.26

Molecular weight: Translated: 15248; Mature: 15116

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIILGADAHGNELKEVLKSFLQQEGFDVTDVTDIDKDFIDNTLAVAQAVNDKDTNLGIM
CEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
VDAYGAGPFMVATKLKGMIAAEVSDERSAYMTRGHNNARMITLGARIVGEELAKNIAKAF
EEECCCCCCHHHHHHCCCEEECCCCCHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHH
VVGSYDGGRHQIRVDMLNKMA
EEECCCCCCEEEEEEHHHHCC
>Mature Secondary Structure 
AIILGADAHGNELKEVLKSFLQQEGFDVTDVTDIDKDFIDNTLAVAQAVNDKDTNLGIM
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
VDAYGAGPFMVATKLKGMIAAEVSDERSAYMTRGHNNARMITLGARIVGEELAKNIAKAF
EEECCCCCCHHHHHHCCCEEECCCCCHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHH
VVGSYDGGRHQIRVDMLNKMA
EEECCCCCCEEEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA