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The map label for this gene is fhuG [H]

Identifier: 195977519

GI number: 195977519

Start: 400164

End: 401186

Strand: Direct

Name: fhuG [H]

Synonym: Sez_0374

Alternate gene names: 195977519

Gene position: 400164-401186 (Clockwise)

Preceding gene: 195977518

Following gene: 195977520

Centisome position: 19.77

GC content: 43.21

Gene sequence:

>1023_bases
ATGCAGCAAGGTAGTCAATATTCTGATCAAGTCACAGCAGCAAGAAAAAGAACCACTAGACTGGTTTATATGATTCTATT
ACTCATGCTGCTGTTTGGCTTAATGCTATATGCGGTCTCTGTTGGGGGCTTATCTGTTTCTTATCAGAGGATATTTAGCG
GCTTATTTGTAGCATATGATCCAGAGGTAGCCCTTATTTATGATTTACGCTTTCCAAGGATTGTGATTACTTTACTGGCT
GGGGCGGGTATATCAACATCTGGAGTCCTGTTTCAGGCGATTTTAAAAAATCCTATTTCAGATCCGGCGATTATTGGGGT
TTGCAGTGGGGCTAGCTTTATGGTCTTGTTATCTAGCCTGCTATTGCCGCAGCTCTTGTTTTATGGTCCTTTGTTATCAT
TTGTGGGAGGCTGTGTTTCTTTTTTGATGATTTATACCTTGTCCTGGAAGAAGGGCTTGCAGCCGATACGTATCATTTTG
ACAGGAATAGCTATCAACGCCTTGTTTTTAGGATTGTCTCGTGCGATTACTGATTTTTCAAAAACCAGCAATCCCTTTGT
CAATGCGCTGCTGTCAGGAAATATTAGCCAAAAAACCTGGGCAGATGTCGGTGTGCTGTGGCCTTATACAGTGCTTGGCT
TGCTGCTTGCGATAGGTCTAGCAAGGCAGTGTGATTTGTTGTTGCTAAACGATGGCTTGATTCGTAATTTAGGCATTGAT
AGTAATTACCTGCGCTTAGGAATCTCACTGGTAGCGGTCTTACTGGCTGCTGTTTCCACCTCGATTGTGGGTGTGGTGTC
ATTTTTAGGCCTGATTGTGCCGCATATTGGCCGCCTTTTAGTTGGTAGTAAGCACAGCTATCTCATTCCTTTTTCTGCCC
TGCTTGGCGCCTTTGTCTTTTTGCTGGCAGATACCTTAGGAAGACAATTGTGTTATCCCTTGGAGATTAGCCCAGCTGTT
ATCATGAGCATTGTCGGGGGACCTTATTTTATTTATCTGTTAAGGAGGTCTGATCTGATATGA

Upstream 100 bases:

>100_bases
TTGGATAATACCCTTTTTGGCATGAGTGCTAAGTTTAACTACAAAGAGGCTTTGAATCATCTGTCACAAATCTTTTATGG
AGCAAAGGAAGTCAACTAAG

Downstream 100 bases:

>100_bases
GTCATGAGCAAGGCTTGATTAGTGTAGAGGATTTGTCCTTTACTTATCGTGATAGGCTTATTTTAGATAGGCTGAGCTTT
ACTATTCCAAAAGGCAAGAT

Product: heme ABC transporter permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQQGSQYSDQVTAARKRTTRLVYMILLLMLLFGLMLYAVSVGGLSVSYQRIFSGLFVAYDPEVALIYDLRFPRIVITLLA
GAGISTSGVLFQAILKNPISDPAIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAIGLARQCDLLLLNDGLIRNLGID
SNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHIGRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAV
IMSIVGGPYFIYLLRRSDLI

Sequences:

>Translated_340_residues
MQQGSQYSDQVTAARKRTTRLVYMILLLMLLFGLMLYAVSVGGLSVSYQRIFSGLFVAYDPEVALIYDLRFPRIVITLLA
GAGISTSGVLFQAILKNPISDPAIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAIGLARQCDLLLLNDGLIRNLGID
SNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHIGRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAV
IMSIVGGPYFIYLLRRSDLI
>Mature_340_residues
MQQGSQYSDQVTAARKRTTRLVYMILLLMLLFGLMLYAVSVGGLSVSYQRIFSGLFVAYDPEVALIYDLRFPRIVITLLA
GAGISTSGVLFQAILKNPISDPAIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAIGLARQCDLLLLNDGLIRNLGID
SNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHIGRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAV
IMSIVGGPYFIYLLRRSDLI

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=322, Percent_Identity=32.6086956521739, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1790741, Length=316, Percent_Identity=33.2278481012658, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1786347, Length=340, Percent_Identity=30.8823529411765, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786804, Length=301, Percent_Identity=29.5681063122924, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786805, Length=290, Percent_Identity=30.6896551724138, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1788004, Length=278, Percent_Identity=27.3381294964029, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36743; Mature: 36743

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQGSQYSDQVTAARKRTTRLVYMILLLMLLFGLMLYAVSVGGLSVSYQRIFSGLFVAYD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHEEEC
PEVALIYDLRFPRIVITLLAGAGISTSGVLFQAILKNPISDPAIIGVCSGASFMVLLSSL
CCEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHH
LLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIILTGIAINALFLGLSRAITDFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAIGLARQCDLLLLNDGLIRNLGID
HCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCC
SNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHIGRLLVGSKHSYLIPFSALLGAFVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHH
LLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLLRRSDLI
HHHHHHHHHCCCCCCCCHHHHHHHHCCHHHEEEEHHCCCC
>Mature Secondary Structure
MQQGSQYSDQVTAARKRTTRLVYMILLLMLLFGLMLYAVSVGGLSVSYQRIFSGLFVAYD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHEEEC
PEVALIYDLRFPRIVITLLAGAGISTSGVLFQAILKNPISDPAIIGVCSGASFMVLLSSL
CCEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHH
LLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIILTGIAINALFLGLSRAITDFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAIGLARQCDLLLLNDGLIRNLGID
HCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCC
SNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHIGRLLVGSKHSYLIPFSALLGAFVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHH
LLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLLRRSDLI
HHHHHHHHHCCCCCCCCHHHHHHHHCCHHHEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]