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The map label for this gene is yabD [H]

Identifier: 195977402

GI number: 195977402

Start: 276443

End: 277216

Strand: Direct

Name: yabD [H]

Synonym: Sez_0255

Alternate gene names: 195977402

Gene position: 276443-277216 (Clockwise)

Preceding gene: 195977400

Following gene: 195977403

Centisome position: 13.66

GC content: 48.58

Gene sequence:

>774_bases
ATGATAGAGATTTTTGATACCCACACACATTTGAATGTGGATCATTTTAATGGCAAAGAGGACGAGGAATTAGCCCTTGC
CAAGGAGCTGGGCGTTAGCTACCATAATGTCGTTGGCTTTGATCAGGAGACTATTGACCAAGCCCTTGCCTTAGCTGATG
CTTATAGAGAGGTTTATGCAACGATTGGCTGGCACCCGACTGAGGCAGGCTCTTACACACAGGCTGTTGAAGATAGGCTG
ATTGCTTGCTTGAAGCACTCAAAGGTTGTTGCCTTAGGAGAGATTGGCTTGGATTATTATTGGATGGAGGACCCCAAGGA
GGTACAGATAGAGGTTTTTAAGCGTCAGCTGCAGCTTGCTAAGGACCATGACCTTCCTTTTGTGGTGCACACGCGTGATG
CCCTTGAGGATACCTATCAGGTTTTAAAGGAGGCTGGAGTAGGGCCTAGGGGTGGTATCATGCATTCCTACTCAGGCTCG
CTTGAGATGGCTCAACGGTTTGTAGATCTGGGTATGCTGATTTCCTTTTCAGGGGTTGTCACCTTTAAAAAGGCGGTTGA
TGTGCAGGAAGCAGCAAGATACCTGCCGCTGGATAAGCTCTTGGTGGAAACAGATGCCCCCTACCTCGCTCCAGTACCAA
AGCGGGGACGTGAAAACCATACCGCCTATACGCGCTATGTTGTTGAGAAAATCGCGGAGCTACGCGGTTTATCAGTAGAA
GAGATAGCTGCAGCAACGACTGCCAATGCAAAGAGGGTGTTTAGGATTGACTGA

Upstream 100 bases:

>100_bases
ACCAAGAGCTATGCTAAGAATGAAGTAGCTGGTAAGATATGGTATAATAATCGAGCAGGTATCCCCTTTAGGGCAATACA
AGAAAGAGGAATGACTAAGA

Downstream 100 bases:

>100_bases
GAAGCTAAAAATTCACGAGGTTATTGTGGTAGAGGGTAAGGACGACACCGCTAATTTACAGCGCTTCTATGATGTCGATA
CCTATGAAACAAAGGGTTCT

Product: putative deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MIEIFDTHTHLNVDHFNGKEDEELALAKELGVSYHNVVGFDQETIDQALALADAYREVYATIGWHPTEAGSYTQAVEDRL
IACLKHSKVVALGEIGLDYYWMEDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARYLPLDKLLVETDAPYLAPVPKRGRENHTAYTRYVVEKIAELRGLSVE
EIAAATTANAKRVFRID

Sequences:

>Translated_257_residues
MIEIFDTHTHLNVDHFNGKEDEELALAKELGVSYHNVVGFDQETIDQALALADAYREVYATIGWHPTEAGSYTQAVEDRL
IACLKHSKVVALGEIGLDYYWMEDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARYLPLDKLLVETDAPYLAPVPKRGRENHTAYTRYVVEKIAELRGLSVE
EIAAATTANAKRVFRID
>Mature_257_residues
MIEIFDTHTHLNVDHFNGKEDEELALAKELGVSYHNVVGFDQETIDQALALADAYREVYATIGWHPTEAGSYTQAVEDRL
IACLKHSKVVALGEIGLDYYWMEDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARYLPLDKLLVETDAPYLAPVPKRGRENHTAYTRYVVEKIAELRGLSVE
EIAAATTANAKRVFRID

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=206, Percent_Identity=35.4368932038835, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI14042943, Length=260, Percent_Identity=26.9230769230769, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI225903439, Length=181, Percent_Identity=30.3867403314917, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI110349730, Length=270, Percent_Identity=28.5185185185185, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI110349734, Length=270, Percent_Identity=28.5185185185185, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI226061853, Length=278, Percent_Identity=28.4172661870504, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=28.6821705426357, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI226061595, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=41.1538461538462, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=35.1351351351351, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=32.5581395348837, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17559024, Length=284, Percent_Identity=27.4647887323944, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=27.9245283018868, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=185, Percent_Identity=31.3513513513514, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=218, Percent_Identity=29.8165137614679, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24586117, Length=200, Percent_Identity=35, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI221330018, Length=200, Percent_Identity=35, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24648690, Length=281, Percent_Identity=27.0462633451957, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28867; Mature: 28867

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIFDTHTHLNVDHFNGKEDEELALAKELGVSYHNVVGFDQETIDQALALADAYREVYA
CEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
TIGWHPTEAGSYTQAVEDRLIACLKHSKVVALGEIGLDYYWMEDPKEVQIEVFKRQLQLA
HCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHH
KDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGSLEMAQRFVDLGMLISFSGVV
HCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
TFKKAVDVQEAARYLPLDKLLVETDAPYLAPVPKRGRENHTAYTRYVVEKIAELRGLSVE
HHHHHHCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
EIAAATTANAKRVFRID
HHHHHHCCCCCEEEECC
>Mature Secondary Structure
MIEIFDTHTHLNVDHFNGKEDEELALAKELGVSYHNVVGFDQETIDQALALADAYREVYA
CEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
TIGWHPTEAGSYTQAVEDRLIACLKHSKVVALGEIGLDYYWMEDPKEVQIEVFKRQLQLA
HCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHH
KDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGSLEMAQRFVDLGMLISFSGVV
HCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
TFKKAVDVQEAARYLPLDKLLVETDAPYLAPVPKRGRENHTAYTRYVVEKIAELRGLSVE
HHHHHHCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
EIAAATTANAKRVFRID
HHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]