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The map label for this gene is lolC [H]

Identifier: 195952832

GI number: 195952832

Start: 394499

End: 395701

Strand: Direct

Name: lolC [H]

Synonym: HY04AAS1_0454

Alternate gene names: 195952832

Gene position: 394499-395701 (Clockwise)

Preceding gene: 195952831

Following gene: 195952833

Centisome position: 25.3

GC content: 33.17

Gene sequence:

>1203_bases
GTGAGATTTAAGGCATTAAAGATAGCTATAAGATATTTGCTCAGTTTTAAAGGAAGTACATTTATCATAAGCTTGATATC
GTTTTTTGGGATTGTGATAAGCACCGCTGGGATACTTCTTACAAACGGCGTTTTTGAAGGATTTCAAGACAATCTTAGAA
TTAAGCTTTTGGGGTCTATGCCAAATTTAATACTGACATACGTAGGAGATAATTCTAAGGCCGATATACCTAAAGTTTTG
GGGCTTTTAGAAAAAAACAAAAAAGATATAAAGATGTTCTCCTATTTCAAGATATATCACGGGGCTATTCAAAGGGGCTC
TTATATAAGTGCTGTCAATGTAGATGCTATGGATTTTGGCAACACTAAAAATTTGAGTTTTTTTGCAAATAAGATAAAAG
GTTCTTTGGATAAAAAAGGTGTTATTCTTGGTAAAGATTTGGCTGCTATGCTTGGGGTGTCAAAAGGTGATTATGTTAGT
ATCATATCGCCTGTGGGTGTACAAACGCCTTTTGGTTATATGCCAAAGGTTCAAAACTTGCCTGTGGTGGGTACTCTTAA
CAGTGGTATATTTGATATAGATTATTCTACCGTGCTTATGGATAACAGTGTTGCAGACAAGCTTTTTGTAAATAATCCGC
CCACAAGAGTCGTTGAGATAAATTTAAAAAATCCATTTTATGCTCCTTCTTTTGCTAAAAGCCTAAAACCTATGATAGGA
GAAAAATTTATAATAACCACTTGGATAGATATGAATAAACCGCTTTTTGAAGCTCTTCAAACCGAAGAAAGAGGTATATT
TTTTGTACTTACTCTCATGATAGTAGTGGCATCTTTTAATATTACAAGCCTTCTTTTTATAAAAGTAAAAGAAAAGCTAA
GAGATATAGCCATATTTAGAGTTTACGGAGAACCAAAATCTTTTATCATGGCTATAATACTTATACAAGGGCTTTTACTT
AGCCTTAGTGGGTTTTTGGTGGGTGTTTTGACGTCTTTTGTTTTGGAGTTTTTTATAAACAAATTTAAACTAATACATGT
CCAAAAAAGCATATACCTTATGTCTTATGTGCCAGTTTCTATATCTTTTAAAGATGTGATGGAGGTCTTTTTGTTGGTGA
TATTTTTAAGCCTTGTGGCAGCTTTTATACCCTCTTATTACGCTGTAAAAGAAAACATAGTAAGGATACTAAGAAATGAC
TGA

Upstream 100 bases:

>100_bases
TACAAACAATCAATCATTGACGCTAAGCTTTTAAAGCCAAAATAGTGGTTTTTGTGTCTTATACATTATATTTTCATTTA
GAATGAGTATAATATAAGCT

Downstream 100 bases:

>100_bases
CGGTATGATAGAACTAAAAAACGTATCAAAAATATACAAAGATAAGCCTGTAGTTGAAGGTTTAAGCCTTTCTATAAAAA
AAGGTGAGTTTGTAGGTATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MRFKALKIAIRYLLSFKGSTFIISLISFFGIVISTAGILLTNGVFEGFQDNLRIKLLGSMPNLILTYVGDNSKADIPKVL
GLLEKNKKDIKMFSYFKIYHGAIQRGSYISAVNVDAMDFGNTKNLSFFANKIKGSLDKKGVILGKDLAAMLGVSKGDYVS
IISPVGVQTPFGYMPKVQNLPVVGTLNSGIFDIDYSTVLMDNSVADKLFVNNPPTRVVEINLKNPFYAPSFAKSLKPMIG
EKFIITTWIDMNKPLFEALQTEERGIFFVLTLMIVVASFNITSLLFIKVKEKLRDIAIFRVYGEPKSFIMAIILIQGLLL
SLSGFLVGVLTSFVLEFFINKFKLIHVQKSIYLMSYVPVSISFKDVMEVFLLVIFLSLVAAFIPSYYAVKENIVRILRND

Sequences:

>Translated_400_residues
MRFKALKIAIRYLLSFKGSTFIISLISFFGIVISTAGILLTNGVFEGFQDNLRIKLLGSMPNLILTYVGDNSKADIPKVL
GLLEKNKKDIKMFSYFKIYHGAIQRGSYISAVNVDAMDFGNTKNLSFFANKIKGSLDKKGVILGKDLAAMLGVSKGDYVS
IISPVGVQTPFGYMPKVQNLPVVGTLNSGIFDIDYSTVLMDNSVADKLFVNNPPTRVVEINLKNPFYAPSFAKSLKPMIG
EKFIITTWIDMNKPLFEALQTEERGIFFVLTLMIVVASFNITSLLFIKVKEKLRDIAIFRVYGEPKSFIMAIILIQGLLL
SLSGFLVGVLTSFVLEFFINKFKLIHVQKSIYLMSYVPVSISFKDVMEVFLLVIFLSLVAAFIPSYYAVKENIVRILRND
>Mature_400_residues
MRFKALKIAIRYLLSFKGSTFIISLISFFGIVISTAGILLTNGVFEGFQDNLRIKLLGSMPNLILTYVGDNSKADIPKVL
GLLEKNKKDIKMFSYFKIYHGAIQRGSYISAVNVDAMDFGNTKNLSFFANKIKGSLDKKGVILGKDLAAMLGVSKGDYVS
IISPVGVQTPFGYMPKVQNLPVVGTLNSGIFDIDYSTVLMDNSVADKLFVNNPPTRVVEINLKNPFYAPSFAKSLKPMIG
EKFIITTWIDMNKPLFEALQTEERGIFFVLTLMIVVASFNITSLLFIKVKEKLRDIAIFRVYGEPKSFIMAIILIQGLLL
SLSGFLVGVLTSFVLEFFINKFKLIHVQKSIYLMSYVPVSISFKDVMEVFLLVIFLSLVAAFIPSYYAVKENIVRILRND

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=391, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787360, Length=403, Percent_Identity=24.5657568238213, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44723; Mature: 44723

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFKALKIAIRYLLSFKGSTFIISLISFFGIVISTAGILLTNGVFEGFQDNLRIKLLGSM
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PNLILTYVGDNSKADIPKVLGLLEKNKKDIKMFSYFKIYHGAIQRGSYISAVNVDAMDFG
CCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
NTKNLSFFANKIKGSLDKKGVILGKDLAAMLGVSKGDYVSIISPVGVQTPFGYMPKVQNL
CCCCHHHHHHHHCCCCCCCCEEECCHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCC
PVVGTLNSGIFDIDYSTVLMDNSVADKLFVNNPPTRVVEINLKNPFYAPSFAKSLKPMIG
CEEEECCCCEEEECCCEEEECCCHHCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHC
EKFIITTWIDMNKPLFEALQTEERGIFFVLTLMIVVASFNITSLLFIKVKEKLRDIAIFR
CCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEE
VYGEPKSFIMAIILIQGLLLSLSGFLVGVLTSFVLEFFINKFKLIHVQKSIYLMSYVPVS
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHEEEEEEECEE
ISFKDVMEVFLLVIFLSLVAAFIPSYYAVKENIVRILRND
ECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFKALKIAIRYLLSFKGSTFIISLISFFGIVISTAGILLTNGVFEGFQDNLRIKLLGSM
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PNLILTYVGDNSKADIPKVLGLLEKNKKDIKMFSYFKIYHGAIQRGSYISAVNVDAMDFG
CCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
NTKNLSFFANKIKGSLDKKGVILGKDLAAMLGVSKGDYVSIISPVGVQTPFGYMPKVQNL
CCCCHHHHHHHHCCCCCCCCEEECCHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCC
PVVGTLNSGIFDIDYSTVLMDNSVADKLFVNNPPTRVVEINLKNPFYAPSFAKSLKPMIG
CEEEECCCCEEEECCCEEEECCCHHCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHC
EKFIITTWIDMNKPLFEALQTEERGIFFVLTLMIVVASFNITSLLFIKVKEKLRDIAIFR
CCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEE
VYGEPKSFIMAIILIQGLLLSLSGFLVGVLTSFVLEFFINKFKLIHVQKSIYLMSYVPVS
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHEEEEEEECEE
ISFKDVMEVFLLVIFLSLVAAFIPSYYAVKENIVRILRND
ECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]