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The map label for this gene is argS [H]

Identifier: 195952792

GI number: 195952792

Start: 358046

End: 359665

Strand: Direct

Name: argS [H]

Synonym: HY04AAS1_0414

Alternate gene names: 195952792

Gene position: 358046-359665 (Clockwise)

Preceding gene: 195952791

Following gene: 195952793

Centisome position: 22.96

GC content: 32.96

Gene sequence:

>1620_bases
ATGAAACAACTAATAAAAGAAATTGTTCAAAAAACCATCAAAAATTTGTACGATGTTGAGATAGAACCCCAGATACAGCT
TCCAAAAGAAGAATCTTACGGAAATTTTGCCTCAAATATAGCTTTTATACTCTCAAAAGCCCTAAAACAAAAACCTCAGG
ATATAGCAATAACTATCGCAGATAACCTAAAAAATCTCCCTCATTTTGAAAAAGTAGAAGCGCTAAATGGCTTTGTAAAT
ATGAAACTATCAAGCGTTTTTTACGAGGGACTTTTGTTTGAGTTTTTAGAAAATCCTATAAACTATATAAAAGATGATGC
CATTTTTGAGGCTTTTGGTATAAAAAAAGAAGATAAGATAAATTTAGAGTATGTGAGTGCAAATCCCACAGGACCCCTTC
ATCTTGGACACGGAAGAGGAGCCGTAATAGGAGATGTGCTTTATAGGCTGTTTAGATTTTTTGATATAAAAGTTGATAGA
GAATACTACATAAACGATGCAGGCAATCAGGTAAACTTACTGGCAAAAAGTGTAATGCATTATATAAACCAGGATTTATA
CCCATTTCCAGAAGATGGCTACAAAGGAGATTATATAAAAGATATAGCAGAGGCGTTTTTAAAAGAGCATAACAAAAGCA
ATATAAACCTCGAAATAAACCTAGAAAGAGTCAAGGATTTTGCAATATCAAAGATGATGGAAGATATAAAGAATACGTTG
AAGCTTTTAAATGTAGAGTTTGATATATATTTTAGTGAAAAGACCCTAAAAGATAAGGTAGAAAAAGTTTTAGAGCTTTT
AAAAGAGAAAAATCTTATAGAAGAAAAAGAAGGGGCTATTTGGTTTAAATCAAAAGATGAAGACAAAGATAGAGTGCTAA
GAAAAAGCGATGGGTCTTATACATACTTTGCTTCTGATATAGCTTATCATCTTGACAAATACCAAAGAGGATACAAAAAA
GCTATAGACCTATGGGGAGCAGATCATCATGGATATATACCACGTTTAAAAGCAGCTTTGGAAGCTCTTGATATACCACA
AGATTGGCTTAGTGTGGAGCTTTTCCAAATCGTAAAGCTTTTTGAAAACGGTCAAGAAGTAAGGATGTCAAAACGCACCG
GCAAGATGCTAAAGCTAATAGATGTAATAGAGGACATAGGAGCAGATAATCTAAGGTTTATGTTCTTAACCAAAAAAGCC
GATACACCCCTTGATATAGATATAAATTTAGTAAAAGCCCAAAACTCTGAAAACCCAGTGTTTTATGTGCAATACGCCTA
TGCAAGGACAATGGGTATAAAAAGACAACTAAAAGAGCCCTTTGTATTTGGCTTTTACAAGGATAAATATACATACGAAG
AAGAGGAATTAGATCTTATAAAACGAATTCTTTCTTCAAAGGACGTGCTTTTTGAAGGAGTTATCAAAAAAGACCCAAGC
CTCGTGGTAAAGTTATCCCTTGATATAGCTAAAAGCTTTCACAAATTTTACAACACCCATAAAGTAATCACTTCAGATGA
AATCACCACAAAAAAACGTATATCCTTAGTTTATGCCACTCAAAAGATATTTGATATTATATTTGATATTTTAAGCATAA
AAGCCCCAGAGATGATGTAA

Upstream 100 bases:

>100_bases
AACCTACGGAAAGTTTATAAAGATAGTAAGCCCGTTCTTGATAATAGCTGGTATATGTGTGATACTTCTGGCAGTTATAA
GACCCTCTTGAGGAGTATAT

Downstream 100 bases:

>100_bases
AAACAAAAGGTCGTAAAGCCCTTTGCCTACCAAATTAGTACCATTGTTTTCGTTGACTAGTACAGAATCCATTTGTCTTA
CAGCCAAGTTGCATATATAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MKQLIKEIVQKTIKNLYDVEIEPQIQLPKEESYGNFASNIAFILSKALKQKPQDIAITIADNLKNLPHFEKVEALNGFVN
MKLSSVFYEGLLFEFLENPINYIKDDAIFEAFGIKKEDKINLEYVSANPTGPLHLGHGRGAVIGDVLYRLFRFFDIKVDR
EYYINDAGNQVNLLAKSVMHYINQDLYPFPEDGYKGDYIKDIAEAFLKEHNKSNINLEINLERVKDFAISKMMEDIKNTL
KLLNVEFDIYFSEKTLKDKVEKVLELLKEKNLIEEKEGAIWFKSKDEDKDRVLRKSDGSYTYFASDIAYHLDKYQRGYKK
AIDLWGADHHGYIPRLKAALEALDIPQDWLSVELFQIVKLFENGQEVRMSKRTGKMLKLIDVIEDIGADNLRFMFLTKKA
DTPLDIDINLVKAQNSENPVFYVQYAYARTMGIKRQLKEPFVFGFYKDKYTYEEEELDLIKRILSSKDVLFEGVIKKDPS
LVVKLSLDIAKSFHKFYNTHKVITSDEITTKKRISLVYATQKIFDIIFDILSIKAPEMM

Sequences:

>Translated_539_residues
MKQLIKEIVQKTIKNLYDVEIEPQIQLPKEESYGNFASNIAFILSKALKQKPQDIAITIADNLKNLPHFEKVEALNGFVN
MKLSSVFYEGLLFEFLENPINYIKDDAIFEAFGIKKEDKINLEYVSANPTGPLHLGHGRGAVIGDVLYRLFRFFDIKVDR
EYYINDAGNQVNLLAKSVMHYINQDLYPFPEDGYKGDYIKDIAEAFLKEHNKSNINLEINLERVKDFAISKMMEDIKNTL
KLLNVEFDIYFSEKTLKDKVEKVLELLKEKNLIEEKEGAIWFKSKDEDKDRVLRKSDGSYTYFASDIAYHLDKYQRGYKK
AIDLWGADHHGYIPRLKAALEALDIPQDWLSVELFQIVKLFENGQEVRMSKRTGKMLKLIDVIEDIGADNLRFMFLTKKA
DTPLDIDINLVKAQNSENPVFYVQYAYARTMGIKRQLKEPFVFGFYKDKYTYEEEELDLIKRILSSKDVLFEGVIKKDPS
LVVKLSLDIAKSFHKFYNTHKVITSDEITTKKRISLVYATQKIFDIIFDILSIKAPEMM
>Mature_539_residues
MKQLIKEIVQKTIKNLYDVEIEPQIQLPKEESYGNFASNIAFILSKALKQKPQDIAITIADNLKNLPHFEKVEALNGFVN
MKLSSVFYEGLLFEFLENPINYIKDDAIFEAFGIKKEDKINLEYVSANPTGPLHLGHGRGAVIGDVLYRLFRFFDIKVDR
EYYINDAGNQVNLLAKSVMHYINQDLYPFPEDGYKGDYIKDIAEAFLKEHNKSNINLEINLERVKDFAISKMMEDIKNTL
KLLNVEFDIYFSEKTLKDKVEKVLELLKEKNLIEEKEGAIWFKSKDEDKDRVLRKSDGSYTYFASDIAYHLDKYQRGYKK
AIDLWGADHHGYIPRLKAALEALDIPQDWLSVELFQIVKLFENGQEVRMSKRTGKMLKLIDVIEDIGADNLRFMFLTKKA
DTPLDIDINLVKAQNSENPVFYVQYAYARTMGIKRQLKEPFVFGFYKDKYTYEEEELDLIKRILSSKDVLFEGVIKKDPS
LVVKLSLDIAKSFHKFYNTHKVITSDEITTKKRISLVYATQKIFDIIFDILSIKAPEMM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=320, Percent_Identity=26.25, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788184, Length=607, Percent_Identity=23.2289950576606, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320548, Length=564, Percent_Identity=21.0992907801418, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321883, Length=226, Percent_Identity=25.6637168141593, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI18859963, Length=574, Percent_Identity=24.9128919860627, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28571570, Length=285, Percent_Identity=29.1228070175439, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62658; Mature: 62658

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLIKEIVQKTIKNLYDVEIEPQIQLPKEESYGNFASNIAFILSKALKQKPQDIAITIA
CHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEE
DNLKNLPHFEKVEALNGFVNMKLSSVFYEGLLFEFLENPINYIKDDAIFEAFGIKKEDKI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NLEYVSANPTGPLHLGHGRGAVIGDVLYRLFRFFDIKVDREYYINDAGNQVNLLAKSVMH
EEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHEEECCEEEECCCCCHHHHHHHHHHH
YINQDLYPFPEDGYKGDYIKDIAEAFLKEHNKSNINLEINLERVKDFAISKMMEDIKNTL
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
KLLNVEFDIYFSEKTLKDKVEKVLELLKEKNLIEEKEGAIWFKSKDEDKDRVLRKSDGSY
HHHEEEEEEEECCHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCCCHHHHHHCCCCCE
TYFASDIAYHLDKYQRGYKKAIDLWGADHHGYIPRLKAALEALDIPQDWLSVELFQIVKL
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FENGQEVRMSKRTGKMLKLIDVIEDIGADNLRFMFLTKKADTPLDIDINLVKAQNSENPV
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCE
FYVQYAYARTMGIKRQLKEPFVFGFYKDKYTYEEEELDLIKRILSSKDVLFEGVIKKDPS
EEEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCC
LVVKLSLDIAKSFHKFYNTHKVITSDEITTKKRISLVYATQKIFDIIFDILSIKAPEMM
EEEEEEHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQLIKEIVQKTIKNLYDVEIEPQIQLPKEESYGNFASNIAFILSKALKQKPQDIAITIA
CHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEE
DNLKNLPHFEKVEALNGFVNMKLSSVFYEGLLFEFLENPINYIKDDAIFEAFGIKKEDKI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NLEYVSANPTGPLHLGHGRGAVIGDVLYRLFRFFDIKVDREYYINDAGNQVNLLAKSVMH
EEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHEEECCEEEECCCCCHHHHHHHHHHH
YINQDLYPFPEDGYKGDYIKDIAEAFLKEHNKSNINLEINLERVKDFAISKMMEDIKNTL
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
KLLNVEFDIYFSEKTLKDKVEKVLELLKEKNLIEEKEGAIWFKSKDEDKDRVLRKSDGSY
HHHEEEEEEEECCHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCCCHHHHHHCCCCCE
TYFASDIAYHLDKYQRGYKKAIDLWGADHHGYIPRLKAALEALDIPQDWLSVELFQIVKL
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FENGQEVRMSKRTGKMLKLIDVIEDIGADNLRFMFLTKKADTPLDIDINLVKAQNSENPV
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCE
FYVQYAYARTMGIKRQLKEPFVFGFYKDKYTYEEEELDLIKRILSSKDVLFEGVIKKDPS
EEEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCC
LVVKLSLDIAKSFHKFYNTHKVITSDEITTKKRISLVYATQKIFDIIFDILSIKAPEMM
EEEEEEHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]