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The map label for this gene is pgsA [H]

Identifier: 195952547

GI number: 195952547

Start: 150932

End: 151576

Strand: Direct

Name: pgsA [H]

Synonym: HY04AAS1_0167

Alternate gene names: 195952547

Gene position: 150932-151576 (Clockwise)

Preceding gene: 195952546

Following gene: 195952548

Centisome position: 9.68

GC content: 34.11

Gene sequence:

>645_bases
TTGAATACTTCAAATATTTTTACAATCCCAAATCTTTTATCATTTTTTAGGCTTTTAATATCTCCATTTTTTTTATTTCT
AGTAAAAGCCGATATAAAGCTAGCGTTTTTTCTATTTATTTTAGTTAGTATCACGGATGCTTTGGACGGGCTTATAGCAA
GGCTTACAAACAGCATAAGCCTTTTGGGCAAACTGCTTGATCCTGTAGCTGATAAAGTTTTGATATTGTCTTTGTCTTTT
GCTTTTATAAGACTAAAGTACCATATGCCAGCTATTCTTTTTAAGCTAATATTGGCTAGAGAGGTGTTTATAATCTTAGG
GAGCTTTTTATTGCTCTATCTTGGTGTAGTGCCAAAGCCCTCTTATCTTGGAAAACTTGCCACGTTTTCTATGATAGTGC
TTTTTTGTGGGCTTTTTATAGAAAATATTAAGAACTACGAAATAAAATTTATAGACTTGCTTTACGATGTAGTAGGTATT
TTTGTAGTGCTTAGTTTCTTAGAATATTTAGAGCGGTGCAACCGCATTTCGGGGCAAAGGAACAGGCATAGCCTCTCCAA
AGCGCAGAGAGCGGCTTGGAAGCACACTTTAAGTATAGGTGTTAGAAATATAATAAGCGCATTAAACCGTAAAGTTTTAA
AATAG

Upstream 100 bases:

>100_bases
CTTTGATGGAAAGTTATAAGATAACCGTTCTTATCATAGAAGAGGACGAAAAGCCCATAGGCATAATACACCTTCACGAC
ATACTGAGGTCTGGTATAAA

Downstream 100 bases:

>100_bases
ATTCATGAAGCTTTTTATAAAGAAGCTTTTTATACTTTTTGTATTTATACTTGTTTTGTTGGCGGCTTCTGGTATAAAAT
CCTTTGGCGTAGGCTCAAGT

Product: CDP-alcohol phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MNTSNIFTIPNLLSFFRLLISPFFLFLVKADIKLAFFLFILVSITDALDGLIARLTNSISLLGKLLDPVADKVLILSLSF
AFIRLKYHMPAILFKLILAREVFIILGSFLLLYLGVVPKPSYLGKLATFSMIVLFCGLFIENIKNYEIKFIDLLYDVVGI
FVVLSFLEYLERCNRISGQRNRHSLSKAQRAAWKHTLSIGVRNIISALNRKVLK

Sequences:

>Translated_214_residues
MNTSNIFTIPNLLSFFRLLISPFFLFLVKADIKLAFFLFILVSITDALDGLIARLTNSISLLGKLLDPVADKVLILSLSF
AFIRLKYHMPAILFKLILAREVFIILGSFLLLYLGVVPKPSYLGKLATFSMIVLFCGLFIENIKNYEIKFIDLLYDVVGI
FVVLSFLEYLERCNRISGQRNRHSLSKAQRAAWKHTLSIGVRNIISALNRKVLK
>Mature_214_residues
MNTSNIFTIPNLLSFFRLLISPFFLFLVKADIKLAFFLFILVSITDALDGLIARLTNSISLLGKLLDPVADKVLILSLSF
AFIRLKYHMPAILFKLILAREVFIILGSFLLLYLGVVPKPSYLGKLATFSMIVLFCGLFIENIKNYEIKFIDLLYDVVGI
FVVLSFLEYLERCNRISGQRNRHSLSKAQRAAWKHTLSIGVRNIISALNRKVLK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI10092647, Length=126, Percent_Identity=38.8888888888889, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI188536108, Length=126, Percent_Identity=38.8888888888889, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1788220, Length=180, Percent_Identity=29.4444444444444, Blast_Score=68, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71984834, Length=119, Percent_Identity=36.9747899159664, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71984838, Length=118, Percent_Identity=37.2881355932203, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320059, Length=196, Percent_Identity=29.5918367346939, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650130, Length=123, Percent_Identity=35.7723577235772, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650126, Length=123, Percent_Identity=35.7723577235772, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650128, Length=123, Percent_Identity=35.7723577235772, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 24350; Mature: 24350

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSNIFTIPNLLSFFRLLISPFFLFLVKADIKLAFFLFILVSITDALDGLIARLTNSIS
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGKLLDPVADKVLILSLSFAFIRLKYHMPAILFKLILAREVFIILGSFLLLYLGVVPKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SYLGKLATFSMIVLFCGLFIENIKNYEIKFIDLLYDVVGIFVVLSFLEYLERCNRISGQR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NRHSLSKAQRAAWKHTLSIGVRNIISALNRKVLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTSNIFTIPNLLSFFRLLISPFFLFLVKADIKLAFFLFILVSITDALDGLIARLTNSIS
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGKLLDPVADKVLILSLSFAFIRLKYHMPAILFKLILAREVFIILGSFLLLYLGVVPKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SYLGKLATFSMIVLFCGLFIENIKNYEIKFIDLLYDVVGIFVVLSFLEYLERCNRISGQR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NRHSLSKAQRAAWKHTLSIGVRNIISALNRKVLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]