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The map label for this gene is ccdB [H]

Identifier: 194738393

GI number: 194738393

Start: 4608200

End: 4608508

Strand: Direct

Name: ccdB [H]

Synonym: SeSA_A4745

Alternate gene names: 194738393

Gene position: 4608200-4608508 (Clockwise)

Preceding gene: 194736825

Following gene: 194737135

Centisome position: 97.86

GC content: 43.37

Gene sequence:

>309_bases
ATGCAATACATGGTTTATCGCAATAAAGGAAACAGCAAGGCTTATCCTTATTTACTTGATGTGCAAAGCGATATTATTGA
TGAACTGCATACTCGCATGGTTATCCCATTGTTTCCTGTGAGCAGGTTGGTAAATAACCCAGTTAAGCGCCTCACGCCCA
CTCTGAATGTGGAAGGTAATGACTATCTGGTGATGACTCACGAAATGGCGAGTATCAGGCTTTCGCAGATTGGTGATGAG
GTGATGGACGTTCGTTCCCACAGGCAAACCATCAAAAATGCTCTCGATTTTATCTTTGACGGGTTCTGA

Upstream 100 bases:

>100_bases
TTGAACGCTGGAAAGCAGAAAATAGAGCGGGTTTGCAGGAGCTCAATCGTATTGCTGATGAGCACGGCCTTTTATCGGAC
GATTACAGGACGTTTTAATC

Downstream 100 bases:

>100_bases
ATGGCTTGCAGGTCAAATGGAGAGTTGTTCACCGTTCTGGAGGGGACTTGACGCGCTTGAACCTGTGGAAGAAGATGAGG
CGTGATTTTAAGTTAGCTGC

Product: cytotoxic protein CcdB

Products: protein histidine; sugar phosphate [C]

Alternate protein names: Protein LetB [H]

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MQYMVYRNKGNSKAYPYLLDVQSDIIDELHTRMVIPLFPVSRLVNNPVKRLTPTLNVEGNDYLVMTHEMASIRLSQIGDE
VMDVRSHRQTIKNALDFIFDGF

Sequences:

>Translated_102_residues
MQYMVYRNKGNSKAYPYLLDVQSDIIDELHTRMVIPLFPVSRLVNNPVKRLTPTLNVEGNDYLVMTHEMASIRLSQIGDE
VMDVRSHRQTIKNALDFIFDGF
>Mature_102_residues
MQYMVYRNKGNSKAYPYLLDVQSDIIDELHTRMVIPLFPVSRLVNNPVKRLTPTLNVEGNDYLVMTHEMASIRLSQIGDE
VMDVRSHRQTIKNALDFIFDGF

Specific function: Killing of plasmid-free segregants. Interferes with the activity of DNA gyrase. Acts to inhibit partitioning of the chromosomal DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002712
- InterPro:   IPR011067 [H]

Pfam domain/function: PF01845 CcdB [H]

EC number: NA

Molecular weight: Translated: 11846; Mature: 11846

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYMVYRNKGNSKAYPYLLDVQSDIIDELHTRMVIPLFPVSRLVNNPVKRLTPTLNVEGN
CCEEEEECCCCCCCCCEEEECHHHHHHHHHHHEECCCCHHHHHHCCCHHHCCCEEEECCC
DYLVMTHEMASIRLSQIGDEVMDVRSHRQTIKNALDFIFDGF
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYMVYRNKGNSKAYPYLLDVQSDIIDELHTRMVIPLFPVSRLVNNPVKRLTPTLNVEGN
CCEEEEECCCCCCCCCEEEECHHHHHHHHHHHEECCCCHHHHHHCCCHHHCCCEEEECCC
DYLVMTHEMASIRLSQIGDEVMDVRSHRQTIKNALDFIFDGF
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-phosphohistidine; sugar [C]

Specific reaction: Protein N-phosphohistidine + sugar = protein histidine + sugar phosphate [C]

General reaction: Acts to inhibit partitioning of the chromosomal DNA [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7926841 [H]