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The map label for this gene is ccdA [C]

Identifier: 194736825

GI number: 194736825

Start: 4607958

End: 4608197

Strand: Direct

Name: ccdA [C]

Synonym: SeSA_A4744

Alternate gene names: 194736825

Gene position: 4607958-4608197 (Clockwise)

Preceding gene: 194735264

Following gene: 194738393

Centisome position: 97.85

GC content: 49.17

Gene sequence:

>240_bases
ATGTCGGGTATGAGTGTACGACATAAAAAAACAGTCAGTGTCACGCTGGAACCTGCATTGCTTCAGCAAGCCCGTGATGC
AGGTATTAATCTGTCTGCGGTGCTTACCGCCGCGCTGAAAGAGGAAATCAGTGCCACAGGCGTTGAACGCTGGAAAGCAG
AAAATAGAGCGGGTTTGCAGGAGCTCAATCGTATTGCTGATGAGCACGGCCTTTTATCGGACGATTACAGGACGTTTTAA

Upstream 100 bases:

>100_bases
GATGTTGCTATCCGAGATAGTCGCCTCTCATTGCCATTTGCTTAAATACTCCCCATACTAGATACATGTGTTTATTACAC
GTGTAATTTCAGGAGGCTCT

Downstream 100 bases:

>100_bases
TCATGCAATACATGGTTTATCGCAATAAAGGAAACAGCAAGGCTTATCCTTATTTACTTGATGTGCAAAGCGATATTATT
GATGAACTGCATACTCGCAT

Product: hypothetical protein

Products: protein histidine; sugar phosphate [C]

Alternate protein names: Post-Segregation Antitoxin CcdA; Antitoxin Of Gyrase Inhibiting xin-Antitoxin System; Antitoxin Of Gyrase; Antitoxin Protein LetA; Protein CcdA; Gyrase Inhibitor Antitoxin

Number of amino acids: Translated: 79; Mature: 78

Protein sequence:

>79_residues
MSGMSVRHKKTVSVTLEPALLQQARDAGINLSAVLTAALKEEISATGVERWKAENRAGLQELNRIADEHGLLSDDYRTF

Sequences:

>Translated_79_residues
MSGMSVRHKKTVSVTLEPALLQQARDAGINLSAVLTAALKEEISATGVERWKAENRAGLQELNRIADEHGLLSDDYRTF
>Mature_78_residues
SGMSVRHKKTVSVTLEPALLQQARDAGINLSAVLTAALKEEISATGVERWKAENRAGLQELNRIADEHGLLSDDYRTF

Specific function: Binds To And Blocks The Activity Of Ccdb. Removes The Bound Letd Protein From The Letd-Gyra Complex By Forming A Leta- Letd Complex. [C]

COG id: COG5302

COG function: function code R; Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 8680; Mature: 8549

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGMSVRHKKTVSVTLEPALLQQARDAGINLSAVLTAALKEEISATGVERWKAENRAGLQ
CCCCCCCCCCEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
ELNRIADEHGLLSDDYRTF
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SGMSVRHKKTVSVTLEPALLQQARDAGINLSAVLTAALKEEISATGVERWKAENRAGLQ
CCCCCCCCCEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
ELNRIADEHGLLSDDYRTF
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-phosphohistidine; sugar [C]

Specific reaction: Protein N-phosphohistidine + sugar = protein histidine + sugar phosphate [C]

General reaction: Removes the bound letD protein from the letD-gyrA complex by forming a letA-letD complex [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA