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The map label for this gene is hcr [H]

Identifier: 194738339

GI number: 194738339

Start: 1022385

End: 1023356

Strand: Reverse

Name: hcr [H]

Synonym: SeSA_A1053

Alternate gene names: 194738339

Gene position: 1023356-1022385 (Counterclockwise)

Preceding gene: 194734432

Following gene: 194737868

Centisome position: 21.73

GC content: 56.07

Gene sequence:

>972_bases
ATGATGACGATGCCAACCTCACAATGTCCCTGGCGAATGCAGGTGCATCACATCCGTCAGGAGACGCCGGATGTATGGAC
AATTGCGCTATTATGCCATGACTACTACCCTTACCGCGCCGGGCAGTATGCGCTGGTGAGCGTGCGTAATTCAGCGGAAA
CGCTGCGCGCCTACACCCTTTCGTCTACGCCGGGCGTCAGTGAATATATCACGCTGACCGTTCGTCGGATTGAAGATGGC
ACGGGTTCACAGTGGTTGACCCATGACATCAAGCGCGGCGATTACATCTGGCTGTCTGATGCAATGGGCGATTTTACCTG
TGACGATAAAACAGAAGATAAGTTTCTGCTGCTCGCCGCCGGTTGTGGCGTAACGCCAATCATGTCGATGCGTCGCTGGC
TGGCGAAATACCGCCCGCAGGCCGATGTGCAGGTCATCTTTAACGTCCGTTCGCCGGATGATGTGATTTTTGCCGACGAG
TGGCGACAGTATCCGGTCACGCTAGTGGCGGAAAATCATGCCACGGAAGGTTTTGTCGCGGGCCGTCTGACCACGGAATT
GTTACAGCGCGTACCGGATTTGGCATCGCGCACCATCATGACCTGCGGCCCGGCGCCCTATATGGATTTCGTCGAACAGG
GCGTGAAAGCGCTTGGCGTAACGCGCTTCTTTAAAGAGAAGTTCTTCACGCCGGTGGCGGAAACGGCAACCAGCGGCCTG
AAATTCACCAAACTACAGCCAGCGCAGGAATTTTATGCCCCGATCGGTACAACGCTGTTGGAGGCGCTGGAGAGTAATAA
AGTACCGGTTGCCGCTGCCTGTCGGGCAGGTGTTTGCGGCTGCTGTAAAACCAAAGTCGTTTCCGGCGACTATACGGTGA
GCAGCACCATGACGCTGAGCGAGGCGGAGATTGCCGAAGGTTACGTACTGGCCTGCTCCTGCCATCCGCAGGGCGATCTT
GTTCTCGCATAA

Upstream 100 bases:

>100_bases
CGCCGGATCTGCTGGCTATCCTCAACGAGAAGTTCGGTCTGCGCTCCGTGACCACCGTTGAAGAAGACATGAAGCAATTG
CTGAGCGCGTAAGGAGGCCA

Downstream 100 bases:

>100_bases
TCGGTAAACGTTCCATAGTAGGCCCGGTAAGCGTTAGCGCCACCGGGCGATTTACCACTCACTTCATCCTTTCGCCCCTC
TCTTCGCCAAAGAAAAACGT

Product: HCP oxidoreductase, NADH-dependent

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTLSSTPGVSEYITLTVRRIEDG
TGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAAGCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADE
WRQYPVTLVAENHATEGFVAGRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTRFFKEKFFTPVAETATSGL
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLSEAEIAEGYVLACSCHPQGDL
VLA

Sequences:

>Translated_323_residues
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTLSSTPGVSEYITLTVRRIEDG
TGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAAGCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADE
WRQYPVTLVAENHATEGFVAGRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTRFFKEKFFTPVAETATSGL
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLSEAEIAEGYVLACSCHPQGDL
VLA
>Mature_323_residues
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTLSSTPGVSEYITLTVRRIEDG
TGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAAGCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADE
WRQYPVTLVAENHATEGFVAGRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTRFFKEKFFTPVAETATSGL
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLSEAEIAEGYVLACSCHPQGDL
VLA

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=322, Percent_Identity=89.1304347826087, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1787658, Length=342, Percent_Identity=26.9005847953216, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788104, Length=323, Percent_Identity=27.2445820433437, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35875; Mature: 35875

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTL
CCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCEEEEEECCCHHHEEEEEE
SSTPGVSEYITLTVRRIEDGTGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAA
CCCCCCCCEEEEEEEEECCCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEE
GCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADEWRQYPVTLVAENHATEGFVA
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCEEEEECCCCCCCEEH
GRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTRFFKEKFFTPVAETATSGL
HHHHHHHHHHCHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCE
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLS
EEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCCEEEECEEEEC
EAEIAEGYVLACSCHPQGDLVLA
HHHHCCCEEEEEEECCCCCEEEC
>Mature Secondary Structure
MMTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYALVSVRNSAETLRAYTL
CCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCEEEEEECCCHHHEEEEEE
SSTPGVSEYITLTVRRIEDGTGSQWLTHDIKRGDYIWLSDAMGDFTCDDKTEDKFLLLAA
CCCCCCCCEEEEEEEEECCCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEE
GCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADEWRQYPVTLVAENHATEGFVA
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCEEEEECCCCCCCEEH
GRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALGVTRFFKEKFFTPVAETATSGL
HHHHHHHHHHCHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCE
KFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAGVCGCCKTKVVSGDYTVSSTMTLS
EEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCCEEEECEEEEC
EAEIAEGYVLACSCHPQGDLVLA
HHHHCCCEEEEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]