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The map label for this gene is pnuC [H]

Identifier: 194737810

GI number: 194737810

Start: 886870

End: 887589

Strand: Direct

Name: pnuC [H]

Synonym: SeSA_A0916

Alternate gene names: 194737810

Gene position: 886870-887589 (Clockwise)

Preceding gene: 194733992

Following gene: 194734297

Centisome position: 18.83

GC content: 51.11

Gene sequence:

>720_bases
ATGGATTTTTTTAGTACGCACAACATACTGATTCATATTCCGATTGGCGCTGGCGGGTACGATCTCTCGTGGATCGAAGC
GGTAGGGACCATCGCCGGCCTGCTCTGTATTTGGCTTGCCAGTCTGGAGAAGATCAGCAACTACTTTTTTGGACTGGTTA
ACGTCACCCTGTTTGCGATTATTTTCTTTCAGATCCAGCTTTATGCCAGCCTGTTGCTGCAACTCTTTTTCTTTGCCGCC
AATATTTATGGCTGGTATGCGTGGTCGCGGCAAACAAAGGATAATCAAGCCGAGCTTAAAATCCGCTGGCTGCCGTTGCC
AAAAGCAATGGCATGGCTGGCGATATGTGTGATAGCTATCGGTTTGATGACGCGATATATCGATCCCGTATTCGCCGTCC
TGACGCGCGTGGCCGTCGCCATTATGCAGATGCTGGGGTTACAGGTGACAATGCCCGTACTGCAACCGGACGCTTTCCCG
TTCTGGGACTCTTGCATGATGGTGCTGTCTATCGCGGCGATGATTCTGATGACACGCAAATATGTCGAAAACTGGCTCCT
GTGGGTGATAATCAACGTGATCAGTGTGGTGATTTTTGCTTTGCAGGGCGTCTATGCGATGTCGCTGGAATATCTGATCC
TGACATTTATCGCCGTGAACGGTAGCCGCCTGTGGATAAACAGCGCGCGGGAGCGAGGATCGCGCGCGCTTTCCCGTTAA

Upstream 100 bases:

>100_bases
TGATGCGGCGCTACGCGAGGGCGCATTACTGCCCCTCAACCGAATGCTGGATTTTGCGACTACACTTCGGGCGTAAAGAC
GGAAATCTTTGGGGGAGAGA

Downstream 100 bases:

>100_bases
TGGTGATGAACATGCCCGGATGGCGTCTGATTCAGATGACAGTCCGGGCCGTGACACACTTGATACTCCATCTGAATCGT
AGCGTGCGCAATATGGTATT

Product: protein PnuC

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYFFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NIYGWYAWSRQTKDNQAELKIRWLPLPKAMAWLAICVIAIGLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFP
FWDSCMMVLSIAAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR

Sequences:

>Translated_239_residues
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYFFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NIYGWYAWSRQTKDNQAELKIRWLPLPKAMAWLAICVIAIGLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFP
FWDSCMMVLSIAAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR
>Mature_239_residues
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYFFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NIYGWYAWSRQTKDNQAELKIRWLPLPKAMAWLAICVIAIGLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFP
FWDSCMMVLSIAAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=239, Percent_Identity=88.2845188284519, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 27163; Mature: 27163

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYFFGLVNVTLFAI
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFQIQLYASLLLQLFFFAANIYGWYAWSRQTKDNQAELKIRWLPLPKAMAWLAICVIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHH
GLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFPFWDSCMMVLSIAAMILMTRK
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
YVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYFFGLVNVTLFAI
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFQIQLYASLLLQLFFFAANIYGWYAWSRQTKDNQAELKIRWLPLPKAMAWLAICVIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHH
GLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFPFWDSCMMVLSIAAMILMTRK
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
YVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIAVNGSRLWINSARERGSRALSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]