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The map label for this gene is nadA [H]

Identifier: 194733992

GI number: 194733992

Start: 885742

End: 886845

Strand: Direct

Name: nadA [H]

Synonym: SeSA_A0915

Alternate gene names: 194733992

Gene position: 885742-886845 (Clockwise)

Preceding gene: 194736266

Following gene: 194737810

Centisome position: 18.81

GC content: 54.26

Gene sequence:

>1104_bases
GTGGCGTTTATTACGCTTTCATTCGGTTGTTTCGTTAAGTCAGTAAAACGAGAAACCACGATGAGCGTAATGTTTGACCC
ACAAGCCGCAATCTACCCGTTCCCGCCGAAACCAACGCCGTTGAACGACGATGAAAAGCAATTTTATCGTGAGAAAATCA
AACGACTCCTCAGCGAACGGGATGCGGTGATGGTGGCGCACTACTACACCGATCCGGAAATTCAACAGTTGGCAGAAGAA
ACCGGCGGCTGTATTTCCGACTCGCTGGAAATGGCCCGTTTCGGCGCGAAGCACGCCGCATCCACGTTACTGGTAGCGGG
CGTACGGTTTATGGGGGAAACCGCCAAAATCCTCAGCCCGGAAAAAACCATTCTTATGCCTACCCTGGCGGCGGAATGTT
CGCTGGATTTAGGCTGCCCAATAGACGAATTTAGCGCTTTTTGTGATGCGCATCCTGACAGAACCGTAGTGGTCTATGCT
AACACCTCGGCTGCTGTTAAAGCGCGTGCGGACTGGGTTGTGACCTCCAGTATCGCCGTAGAACTGATTGAGCATCTGGA
TAGTTTGGGGGAAAAAATTATCTGGGCGCCGGACAGACACCTGGGGAATTACGTGCAAAAACAGACCGGGGCCGATGTAC
TGTGTTGGCAAGGGGCGTGTATCGTGCATGACGAGTTTAAAACCCAGGCGTTGACCCGTTTAAAAAAAATCTATCCCGAT
GCCGCTCTTCTGGTTCACCCTGAATCGCCGCAGTCCATTGTCGAAATGGCCGATGCGGTGGGCTCCACCAGTCAGCTTAT
TAAGGCGGCAAAAACGCTGCCGCACAGACAGCTTATCGTGGCGACCGATCGCGGCATCTTCTACAAAATGCAGCAGGCGG
TGCCTGAAAAAGAGCTGCTTGAAGCGCCCACGGCTGGCGAGGGGGCGACCTGCCGTAGCTGCGCGCACTGTCCGTGGATG
GCGATGAATGGCCTGAAAACCATTGCTGAAGGGCTGGAGCAGGGAGGCGCGGCGCATGAAATACAGGTTGATGCGGCGCT
ACGCGAGGGCGCATTACTGCCCCTCAACCGAATGCTGGATTTTGCGACTACACTTCGGGCGTAA

Upstream 100 bases:

>100_bases
TAAGACGTTACGCCGCCATCAAACACGGGCTACGTAATTATTGTGACTTTCCTTATTGAATCAGCTATCTTGTTTAGCAT
ATAAAACAAATTAACCGATT

Downstream 100 bases:

>100_bases
AGACGGAAATCTTTGGGGGAGAGAATGGATTTTTTTAGTACGCACAACATACTGATTCATATTCCGATTGGCGCTGGCGG
GTACGATCTCTCGTGGATCG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MAFITLSFGCFVKSVKRETTMSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLSERDAVMVAHYYTDPEIQQLAEE
TGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPEKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYA
NTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPD
AALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELLEAPTAGEGATCRSCAHCPWM
AMNGLKTIAEGLEQGGAAHEIQVDAALREGALLPLNRMLDFATTLRA

Sequences:

>Translated_367_residues
MAFITLSFGCFVKSVKRETTMSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLSERDAVMVAHYYTDPEIQQLAEE
TGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPEKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYA
NTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPD
AALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELLEAPTAGEGATCRSCAHCPWM
AMNGLKTIAEGLEQGGAAHEIQVDAALREGALLPLNRMLDFATTLRA
>Mature_366_residues
AFITLSFGCFVKSVKRETTMSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLSERDAVMVAHYYTDPEIQQLAEET
GGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPEKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYAN
TSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPDA
ALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELLEAPTAGEGATCRSCAHCPWMA
MNGLKTIAEGLEQGGAAHEIQVDAALREGALLPLNRMLDFATTLRA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=347, Percent_Identity=87.8962536023055, Blast_Score=644, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40182; Mature: 40050

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFITLSFGCFVKSVKRETTMSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLSER
CEEEEEEHHHHHHHHHHHHEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
DAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSP
CEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHCCC
EKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
CCEEEEEHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHH
ELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPD
HHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHHCCC
AALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELL
CEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCHHHHH
EAPTAGEGATCRSCAHCPWMAMNGLKTIAEGLEQGGAAHEIQVDAALREGALLPLNRMLD
CCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCHHHHHH
FATTLRA
HHHHHCC
>Mature Secondary Structure 
AFITLSFGCFVKSVKRETTMSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLSER
EEEEEEHHHHHHHHHHHHEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
DAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSP
CEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHCCC
EKTILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
CCEEEEEHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHH
ELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPD
HHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHHCCC
AALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELL
CEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCHHHHH
EAPTAGEGATCRSCAHCPWMAMNGLKTIAEGLEQGGAAHEIQVDAALREGALLPLNRMLD
CCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCHHHHHH
FATTLRA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA