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The map label for this gene is lptA [H]

Identifier: 194737776

GI number: 194737776

Start: 3382208

End: 3382762

Strand: Direct

Name: lptA [H]

Synonym: SeSA_A3510

Alternate gene names: 194737776

Gene position: 3382208-3382762 (Clockwise)

Preceding gene: 194736180

Following gene: 194735191

Centisome position: 71.82

GC content: 53.15

Gene sequence:

>555_bases
ATGAAATTCAAAACAAACAAACTCAGCCTTAATCTTATGCTTGCCGGCTCGCTGCTGGCCGCCAGCATTCCGGCTTTCGC
CGTCACGGGCGATACCGAACAGCCTATTCATATTGACTCGGATCAACAGTCGCTGGATATGCAAGGCAACGTCGTGACCT
TTACGGGCAACGTGGTGATGACCCAGGGCACGATTAAGATCAACGCCGATAAAGTCGTGGTTACCCGCCCTGGCGGCGAA
CAGGGGAAAGAGGTGATCGACGGTTACGGCAATCCGGCCACCTTCTACCAGATGCAGGACAACGGTAAGCCGGTGAAAGG
CCACGCTTCCCATATGCACTACGAGCTGGCGAAAGATTTTGTGGTGCTAACCGGCAACGCTTATCTGGAGCAGCTTGACA
GCAACATTACCGGCGACAAAATCACCTACCTGGTGAAAGAGCAGAAAATGCAGGCCTTCAGCGAGAAAGGCAAACGCGTC
ACCACCGTTCTGGTGCCGTCGCAGTTGCAAGACAAAAACAAAGGCCAGACTCCGGCGCAAAAGAAGAGTAACTAA

Upstream 100 bases:

>100_bases
GTGACGTTATACGGCACAACATTTAACTCCAGCGGACTGAAAATGCGCGGTAACTTACGCAGCAAGAACGCCGAGCTGAT
TGAAAAGGTTAGAACCTCTT

Downstream 100 bases:

>100_bases
TTCGTTATGGCAACATTAACTGCAAAGAATCTGGCGAAGGCCTATAAAGGCCGTCGCGTAGTGGAAGATGTCAGTCTGAC
CGTTAACTCCGGGGAGATTG

Product: lipopolysaccharide transport periplasmic protein LptA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MKFKTNKLSLNLMLAGSLLAASIPAFAVTGDTEQPIHIDSDQQSLDMQGNVVTFTGNVVMTQGTIKINADKVVVTRPGGE
QGKEVIDGYGNPATFYQMQDNGKPVKGHASHMHYELAKDFVVLTGNAYLEQLDSNITGDKITYLVKEQKMQAFSEKGKRV
TTVLVPSQLQDKNKGQTPAQKKSN

Sequences:

>Translated_184_residues
MKFKTNKLSLNLMLAGSLLAASIPAFAVTGDTEQPIHIDSDQQSLDMQGNVVTFTGNVVMTQGTIKINADKVVVTRPGGE
QGKEVIDGYGNPATFYQMQDNGKPVKGHASHMHYELAKDFVVLTGNAYLEQLDSNITGDKITYLVKEQKMQAFSEKGKRV
TTVLVPSQLQDKNKGQTPAQKKSN
>Mature_184_residues
MKFKTNKLSLNLMLAGSLLAASIPAFAVTGDTEQPIHIDSDQQSLDMQGNVVTFTGNVVMTQGTIKINADKVVVTRPGGE
QGKEVIDGYGNPATFYQMQDNGKPVKGHASHMHYELAKDFVVLTGNAYLEQLDSNITGDKITYLVKEQKMQAFSEKGKRV
TTVLVPSQLQDKNKGQTPAQKKSN

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=185, Percent_Identity=91.8918918918919, Blast_Score=347, Evalue=4e-97,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 20059; Mature: 20059

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKTNKLSLNLMLAGSLLAASIPAFAVTGDTEQPIHIDSDQQSLDMQGNVVTFTGNVVM
CCEECCEEEEEEEEECCHHHHCCCEEEEECCCCCCEEECCCCCCCCCCCCEEEEECCEEE
TQGTIKINADKVVVTRPGGEQGKEVIDGYGNPATFYQMQDNGKPVKGHASHMHYELAKDF
EECEEEECCCEEEEECCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHEECCCCE
VVLTGNAYLEQLDSNITGDKITYLVKEQKMQAFSEKGKRVTTVLVPSQLQDKNKGQTPAQ
EEEECCHHHHHHCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEEECCHHCCCCCCCCCCC
KKSN
CCCC
>Mature Secondary Structure
MKFKTNKLSLNLMLAGSLLAASIPAFAVTGDTEQPIHIDSDQQSLDMQGNVVTFTGNVVM
CCEECCEEEEEEEEECCHHHHCCCEEEEECCCCCCEEECCCCCCCCCCCCEEEEECCEEE
TQGTIKINADKVVVTRPGGEQGKEVIDGYGNPATFYQMQDNGKPVKGHASHMHYELAKDF
EECEEEECCCEEEEECCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHEECCCCE
VVLTGNAYLEQLDSNITGDKITYLVKEQKMQAFSEKGKRVTTVLVPSQLQDKNKGQTPAQ
EEEECCHHHHHHCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEEECCHHCCCCCCCCCCC
KKSN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]