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The map label for this gene is clpP3 [H]

Identifier: 194737695

GI number: 194737695

Start: 671508

End: 673577

Strand: Direct

Name: clpP3 [H]

Synonym: SeSA_A0695

Alternate gene names: 194737695

Gene position: 671508-673577 (Clockwise)

Preceding gene: 194734641

Following gene: 194738176

Centisome position: 14.26

GC content: 57.49

Gene sequence:

>2070_bases
ATGGCAGCCGCGCGCGGGAAGAACGAAAGCGGCGCTGAATCCTGGTACACCATCCGCGCGGCGGCGAATAACGCGGCCGA
TATCAGTATTTACGATGAAATTGGTGGCTGGGGAATTTCGGCGCACTGGTTTGCCGAAGAGCTGGTGGCCCTGGGGAGTA
TCACGCAGATCAACCTGCATATTCATTCCCCGGGTGGCAGTATTTTCGACGGGCTGGCCATTTACAATCTGCTGAAAAAT
CACCCGGCGAGAAAAGTGGTGTATGTGGACGGTGTGGCCTGTTCGATGGCGTCGGTCATCGCGATGGTGGGCGACCCCGT
CATCATGCCGGAAAACGCGATGATGATGATCCACCGCCCACGCGGTATTGCCGGTGGTGAGTCCTCTGATATCCGCGACT
ATGCCGATCTGCTCGACAAGATGGAAAGCGTCATCATCCCGATTTACGCCGAAAAAACGGGGAAGTCACCGGACGATATT
GCCGCGCTGCTCGCCAGTGAGACCTGGATGAGTGGTGCCGAGTGTGTCCGGGAAGGCTTTGCCGACAAAGTTATTCAGCC
CGTCCGGGCAATGGCTCAGCTGTATTCAAAACGACTTGAGGAATTTGAACATATGCCACAGAACGTCAAAAACATGATTA
TTGCCCCCCAGGGTAACGCCGGGACACTGACGCAGCCGGAGCCGCAGGCCATCGTGACCCCGCCGCCGGTGGCGGTCACC
ACACCGTCGCCACAACCTGCTACCACTGCTCCGGGGACGGATGAAATCACCCTGCGCGCCCGTTTTCAGGAAGAGCAGCG
ACAGCGTATCAGCGGGATCCAGAATGTGTTTGGTATGTTCGGTAACCGCCACGGCGAGCTGATGGCGCAGTGCATTGCGG
ATGTGGACTGCAATGTGGACGCGGCGAAAGACAAACTACTGGAGGCACTGGGCAGGGGGGTGACACCCACCAATACGCTG
GGCGGGACGCAGAACACACATAATCCGATGCTCTCCCATATCTATGCGGGCAACGGTAACTTTGCCGGGGACGGCATCCG
GGCTTCCCTGATGGCACGGGCGGGGTTTGAAAGCAGCCAGGCCGATAACCCGTATAACGCCATGACCATGCGGGAACTGG
CGCGTATGTCACTGACCGAACGTGGCGTGGGTGTCTCGACACTCAATCCGATGCAGATGGTCGGGATGGCGTTCACGCAC
AGCACCTCAGATTTCGGCAATATTCTGCTGGATGTGGCGAACAAGGCCATTCTTCAGGGCTGGGAGGAAGCCCCGGAAAC
CTACGAACAGTGGACGCGCAAAGGCCAGCTTTCTGACTTTAAAACGGCACACCGTGTGGGTATGGGGGGCTTTAATGCCC
TGCGTCAGGTGCGCGAAGGGGCGGAATATAAGTACGTCACCACCGGGGACAAACAGGCCACCATTGCTCTGGCAACCTAC
GGGGAACTGTTCAGCATCACCCGTCAGGCCATCATTAACGACGATCTGAACATGCTGACCGATGTCCCGATGAAGCTGGG
GCGGGCAGCGAAGTCCACCATTGCCGATCTGGTTTATGCCATTCTGACCGCCAACCCGAAAATGTCCACGGACAACGTGA
ACCTGTTCGACAAGGCGAAACACGCGAACGTACTGGAAGGGGCGCTGATGGATGTGGCATCACTGGATAAAGCCCGCCAG
CTGATGCGCACCCAGAAAGAAGGTGAGCGTCACCTGAATATTCGTCCGGCATTCGTGCTGGTGCCGACAGCACTGGAGTC
CGTCACTAACCAGGTGATCAGATCCACGAGTGTGAAAGGCGCGGACATTAACGCCGGCATTATTAACCCGGTGAAAGATT
TTGCGACCGTCATCGCCGAGCCGCGTCTGGACGATAACAGCCAGTCCACCTTTTATCTGGCTGCCGCCAAAGGCACTGAC
ACGATTGAAGTGGCTTATCTCAATGGTGTGGATACACCGTATATCGATCAGCAGGACGGTTTCAGCGTCGACGGCGTGAC
CACCAAAGTGCGTATCGATGCCGGGGTGGCGCCGGTCGATCACCGCGGTCTGGTGAAGTGTTCCGCGTAA

Upstream 100 bases:

>100_bases
AAGCTGGGGCTGGTGTTTGACACCGATCCGGCGCATGAAACCGGAGAACGATCCGATGTTAAAGAGGAAAAAAAGGACCC
TGAACAGTCCACCCAGGGCG

Downstream 100 bases:

>100_bases
CCACCCAAAATAACCATCCGAGTGGCCCGTCAGGGCTTTTTTTACGCCTGAAATCCGGGCATTCGTGACCGGACCGGAGA
AAATCATTATGGCAAAGAAT

Product: ATP-dependent protease

Products: NA

Alternate protein names: Endopeptidase Clp 3 [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MAAARGKNESGAESWYTIRAAANNAADISIYDEIGGWGISAHWFAEELVALGSITQINLHIHSPGGSIFDGLAIYNLLKN
HPARKVVYVDGVACSMASVIAMVGDPVIMPENAMMMIHRPRGIAGGESSDIRDYADLLDKMESVIIPIYAEKTGKSPDDI
AALLASETWMSGAECVREGFADKVIQPVRAMAQLYSKRLEEFEHMPQNVKNMIIAPQGNAGTLTQPEPQAIVTPPPVAVT
TPSPQPATTAPGTDEITLRARFQEEQRQRISGIQNVFGMFGNRHGELMAQCIADVDCNVDAAKDKLLEALGRGVTPTNTL
GGTQNTHNPMLSHIYAGNGNFAGDGIRASLMARAGFESSQADNPYNAMTMRELARMSLTERGVGVSTLNPMQMVGMAFTH
STSDFGNILLDVANKAILQGWEEAPETYEQWTRKGQLSDFKTAHRVGMGGFNALRQVREGAEYKYVTTGDKQATIALATY
GELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADLVYAILTANPKMSTDNVNLFDKAKHANVLEGALMDVASLDKARQ
LMRTQKEGERHLNIRPAFVLVPTALESVTNQVIRSTSVKGADINAGIINPVKDFATVIAEPRLDDNSQSTFYLAAAKGTD
TIEVAYLNGVDTPYIDQQDGFSVDGVTTKVRIDAGVAPVDHRGLVKCSA

Sequences:

>Translated_689_residues
MAAARGKNESGAESWYTIRAAANNAADISIYDEIGGWGISAHWFAEELVALGSITQINLHIHSPGGSIFDGLAIYNLLKN
HPARKVVYVDGVACSMASVIAMVGDPVIMPENAMMMIHRPRGIAGGESSDIRDYADLLDKMESVIIPIYAEKTGKSPDDI
AALLASETWMSGAECVREGFADKVIQPVRAMAQLYSKRLEEFEHMPQNVKNMIIAPQGNAGTLTQPEPQAIVTPPPVAVT
TPSPQPATTAPGTDEITLRARFQEEQRQRISGIQNVFGMFGNRHGELMAQCIADVDCNVDAAKDKLLEALGRGVTPTNTL
GGTQNTHNPMLSHIYAGNGNFAGDGIRASLMARAGFESSQADNPYNAMTMRELARMSLTERGVGVSTLNPMQMVGMAFTH
STSDFGNILLDVANKAILQGWEEAPETYEQWTRKGQLSDFKTAHRVGMGGFNALRQVREGAEYKYVTTGDKQATIALATY
GELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADLVYAILTANPKMSTDNVNLFDKAKHANVLEGALMDVASLDKARQ
LMRTQKEGERHLNIRPAFVLVPTALESVTNQVIRSTSVKGADINAGIINPVKDFATVIAEPRLDDNSQSTFYLAAAKGTD
TIEVAYLNGVDTPYIDQQDGFSVDGVTTKVRIDAGVAPVDHRGLVKCSA
>Mature_688_residues
AAARGKNESGAESWYTIRAAANNAADISIYDEIGGWGISAHWFAEELVALGSITQINLHIHSPGGSIFDGLAIYNLLKNH
PARKVVYVDGVACSMASVIAMVGDPVIMPENAMMMIHRPRGIAGGESSDIRDYADLLDKMESVIIPIYAEKTGKSPDDIA
ALLASETWMSGAECVREGFADKVIQPVRAMAQLYSKRLEEFEHMPQNVKNMIIAPQGNAGTLTQPEPQAIVTPPPVAVTT
PSPQPATTAPGTDEITLRARFQEEQRQRISGIQNVFGMFGNRHGELMAQCIADVDCNVDAAKDKLLEALGRGVTPTNTLG
GTQNTHNPMLSHIYAGNGNFAGDGIRASLMARAGFESSQADNPYNAMTMRELARMSLTERGVGVSTLNPMQMVGMAFTHS
TSDFGNILLDVANKAILQGWEEAPETYEQWTRKGQLSDFKTAHRVGMGGFNALRQVREGAEYKYVTTGDKQATIALATYG
ELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADLVYAILTANPKMSTDNVNLFDKAKHANVLEGALMDVASLDKARQL
MRTQKEGERHLNIRPAFVLVPTALESVTNQVIRSTSVKGADINAGIINPVKDFATVIAEPRLDDNSQSTFYLAAAKGTDT
IEVAYLNGVDTPYIDQQDGFSVDGVTTKVRIDAGVAPVDHRGLVKCSA

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=132, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538017, Length=131, Percent_Identity=34.3511450381679, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129427, Length=133, Percent_Identity=30.8270676691729, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 74408; Mature: 74277

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAARGKNESGAESWYTIRAAANNAADISIYDEIGGWGISAHWFAEELVALGSITQINLH
CCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEE
IHSPGGSIFDGLAIYNLLKNHPARKVVYVDGVACSMASVIAMVGDPVIMPENAMMMIHRP
EECCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEECCCCCEEEEECC
RGIAGGESSDIRDYADLLDKMESVIIPIYAEKTGKSPDDIAALLASETWMSGAECVREGF
CCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
ADKVIQPVRAMAQLYSKRLEEFEHMPQNVKNMIIAPQGNAGTLTQPEPQAIVTPPPVAVT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEECCCCCCCCCCCCCCEEECCCCEEEE
TPSPQPATTAPGTDEITLRARFQEEQRQRISGIQNVFGMFGNRHGELMAQCIADVDCNVD
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
AAKDKLLEALGRGVTPTNTLGGTQNTHNPMLSHIYAGNGNFAGDGIRASLMARAGFESSQ
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCHHHHHHHHCCCCCCC
ADNPYNAMTMRELARMSLTERGVGVSTLNPMQMVGMAFTHSTSDFGNILLDVANKAILQG
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
WEEAPETYEQWTRKGQLSDFKTAHRVGMGGFNALRQVREGAEYKYVTTGDKQATIALATY
HHCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCEEEEEEHH
GELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADLVYAILTANPKMSTDNVNLFDKAK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
HANVLEGALMDVASLDKARQLMRTQKEGERHLNIRPAFVLVPTALESVTNQVIRSTSVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
ADINAGIINPVKDFATVIAEPRLDDNSQSTFYLAAAKGTDTIEVAYLNGVDTPYIDQQDG
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCC
FSVDGVTTKVRIDAGVAPVDHRGLVKCSA
CEECCEEEEEEEECCCCCCCCCCCEEECC
>Mature Secondary Structure 
AAARGKNESGAESWYTIRAAANNAADISIYDEIGGWGISAHWFAEELVALGSITQINLH
CCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEE
IHSPGGSIFDGLAIYNLLKNHPARKVVYVDGVACSMASVIAMVGDPVIMPENAMMMIHRP
EECCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEECCCCCEEEEECC
RGIAGGESSDIRDYADLLDKMESVIIPIYAEKTGKSPDDIAALLASETWMSGAECVREGF
CCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
ADKVIQPVRAMAQLYSKRLEEFEHMPQNVKNMIIAPQGNAGTLTQPEPQAIVTPPPVAVT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEECCCCCCCCCCCCCCEEECCCCEEEE
TPSPQPATTAPGTDEITLRARFQEEQRQRISGIQNVFGMFGNRHGELMAQCIADVDCNVD
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
AAKDKLLEALGRGVTPTNTLGGTQNTHNPMLSHIYAGNGNFAGDGIRASLMARAGFESSQ
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCHHHHHHHHCCCCCCC
ADNPYNAMTMRELARMSLTERGVGVSTLNPMQMVGMAFTHSTSDFGNILLDVANKAILQG
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
WEEAPETYEQWTRKGQLSDFKTAHRVGMGGFNALRQVREGAEYKYVTTGDKQATIALATY
HHCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCEEEEEEHH
GELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADLVYAILTANPKMSTDNVNLFDKAK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
HANVLEGALMDVASLDKARQLMRTQKEGERHLNIRPAFVLVPTALESVTNQVIRSTSVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
ADINAGIINPVKDFATVIAEPRLDDNSQSTFYLAAAKGTDTIEVAYLNGVDTPYIDQQDG
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCC
FSVDGVTTKVRIDAGVAPVDHRGLVKCSA
CEECCEEEEEEEECCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]