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The map label for this gene is yafC [H]

Identifier: 194737606

GI number: 194737606

Start: 297900

End: 298814

Strand: Reverse

Name: yafC [H]

Synonym: SeSA_A0286

Alternate gene names: 194737606

Gene position: 298814-297900 (Counterclockwise)

Preceding gene: 194734347

Following gene: 194735955

Centisome position: 6.35

GC content: 50.6

Gene sequence:

>915_bases
ATGAAAGCCACCTCCGAAGAACTTGCAATTTTTGTCGCTGTCGTGGAAAGCGGCAGCTTCAGCCGGGCGGCAGAGCAGCT
TGGACAGGCCAATTCCGCTGTCAGCCGGGCAGTTAAAAAGCTGGAGATGAAGCTCGGCGTCAGTCTGCTTAATCGTACGA
CCCGACAGCTGAGCCTGACTGAAGAAGGAGAGCGATACTTCAGGCGTGTGCAGCAGATACTGCAAGAAATGGCCGCTGCA
GAAACGGAAATCATGGAGTCGCGTAATACCCCGCGCGGCTTACTGCGTATCGATGCGGCAACGCCGGTAATGCTGCATTT
CCTGATGCCGCTGATTAAACCTTTTCGTGAACGGTATCCTGAAATAACGTTGTCTCTTGTCTCCTCAGAAACGTTCATCA
ATCTTATTGAACGAAAAGTGGATGTTGCGATACGCGCAGGCACGTTGACAGATTCAAGTCTGCGCGCGCGTCCGTTATTT
ACCAGTTATCGTAAGATTATCGCTTCACCGGATTATATTGCCCGTTTTGGCAAGCCAGAGACCGTTGAAGAGTTAAAACG
GCATCTGTGCCTGGGGTTCTCAGAACCTGTTTCGCTCAATACCTGGCCAATAGCCTGTAGCGATGGGCAGCTCCATGAGG
TTGAATGTGGGATTTCTTCCAACAGCGGGGAAACGTTAAAACAACTTTGCCTGAACGGTAACGGCATTGCATGTCTTTCA
GATTATATGATTGATAAAGAGATCGCGCGGGGAGAACTGGTGGAACTGCTGGCCGATAAACGTCTGCCGGTAGAAATGCC
TTTCAGCGCCGTTTACTACAGCGATCGCGCCGTCAGCACACGCATTCGGGCATTTATCGACTTTTTGAGCGAATATATAA
GAACAGCTCCCGAAGGAGCTGTGAAAGAGGGGTAA

Upstream 100 bases:

>100_bases
AACTCCATAACAACAGTAATCAGATGACACGCAGTATGCCTGGATGTTTTAATGACAAAAATAGCCAAAATATCAATTTA
ATTTTGCTGCAGGAGCAAAA

Downstream 100 bases:

>100_bases
AGGGTACAAAGGGTCAGGCAATTAATCCCACTCAGGGGCCAGACCTTCCGGGCTAACCAGGCGGTCGTTGCAATCCAGTG
CCGCGATCGCATTTTTATCT

Product: LysR substrate binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKATSEELAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLEMKLGVSLLNRTTRQLSLTEEGERYFRRVQQILQEMAAA
ETEIMESRNTPRGLLRIDAATPVMLHFLMPLIKPFRERYPEITLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLF
TSYRKIIASPDYIARFGKPETVEELKRHLCLGFSEPVSLNTWPIACSDGQLHEVECGISSNSGETLKQLCLNGNGIACLS
DYMIDKEIARGELVELLADKRLPVEMPFSAVYYSDRAVSTRIRAFIDFLSEYIRTAPEGAVKEG

Sequences:

>Translated_304_residues
MKATSEELAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLEMKLGVSLLNRTTRQLSLTEEGERYFRRVQQILQEMAAA
ETEIMESRNTPRGLLRIDAATPVMLHFLMPLIKPFRERYPEITLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLF
TSYRKIIASPDYIARFGKPETVEELKRHLCLGFSEPVSLNTWPIACSDGQLHEVECGISSNSGETLKQLCLNGNGIACLS
DYMIDKEIARGELVELLADKRLPVEMPFSAVYYSDRAVSTRIRAFIDFLSEYIRTAPEGAVKEG
>Mature_304_residues
MKATSEELAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLEMKLGVSLLNRTTRQLSLTEEGERYFRRVQQILQEMAAA
ETEIMESRNTPRGLLRIDAATPVMLHFLMPLIKPFRERYPEITLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLF
TSYRKIIASPDYIARFGKPETVEELKRHLCLGFSEPVSLNTWPIACSDGQLHEVECGISSNSGETLKQLCLNGNGIACLS
DYMIDKEIARGELVELLADKRLPVEMPFSAVYYSDRAVSTRIRAFIDFLSEYIRTAPEGAVKEG

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=304, Percent_Identity=90.1315789473684, Blast_Score=570, Evalue=1e-164,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=34.0277777777778, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=29.7297297297297, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=28.5714285714286, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=31.4878892733564, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=29.2096219931272, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=28.4722222222222, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789173, Length=282, Percent_Identity=29.0780141843972, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI157672245, Length=172, Percent_Identity=35.4651162790698, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788706, Length=298, Percent_Identity=26.510067114094, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=25.752508361204, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786448, Length=259, Percent_Identity=27.4131274131274, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082132, Length=301, Percent_Identity=28.2392026578073, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI145693105, Length=164, Percent_Identity=30.4878048780488, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=126, Percent_Identity=34.9206349206349, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786508, Length=260, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790262, Length=170, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787806, Length=169, Percent_Identity=26.6272189349112, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789506, Length=311, Percent_Identity=23.1511254019293, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789492, Length=261, Percent_Identity=26.0536398467433, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33945; Mature: 33945

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATSEELAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLEMKLGVSLLNRTTRQLSLT
CCCCHHHHEEEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EEGERYFRRVQQILQEMAAAETEIMESRNTPRGLLRIDAATPVMLHFLMPLIKPFRERYP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCC
EITLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLFTSYRKIIASPDYIARFGKPE
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCH
TVEELKRHLCLGFSEPVSLNTWPIACSDGQLHEVECGISSNSGETLKQLCLNGNGIACLS
HHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEHH
DYMIDKEIARGELVELLADKRLPVEMPFSAVYYSDRAVSTRIRAFIDFLSEYIRTAPEGA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHCCCCCC
VKEG
CCCC
>Mature Secondary Structure
MKATSEELAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLEMKLGVSLLNRTTRQLSLT
CCCCHHHHEEEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EEGERYFRRVQQILQEMAAAETEIMESRNTPRGLLRIDAATPVMLHFLMPLIKPFRERYP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCC
EITLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLFTSYRKIIASPDYIARFGKPE
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCH
TVEELKRHLCLGFSEPVSLNTWPIACSDGQLHEVECGISSNSGETLKQLCLNGNGIACLS
HHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEHH
DYMIDKEIARGELVELLADKRLPVEMPFSAVYYSDRAVSTRIRAFIDFLSEYIRTAPEGA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHCCCCCC
VKEG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]