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The map label for this gene is yncB [H]

Identifier: 194737426

GI number: 194737426

Start: 1647831

End: 1648868

Strand: Reverse

Name: yncB [H]

Synonym: SeSA_A1707

Alternate gene names: 194737426

Gene position: 1648868-1647831 (Counterclockwise)

Preceding gene: 194738390

Following gene: 194736903

Centisome position: 35.01

GC content: 53.85

Gene sequence:

>1038_bases
ATGAAGCAACAGACCAACCGAAATCGTCGTTGGGTTTTGGCCTCGCGTCCCCACGGCGCGCCGCAGATGGATAACTTCCG
CCTCGAAGAAGATGACGTCGCGACGCCCGGTGAAGGGCAGGTGCTATTGCGTACCGTTTTTTTATCACTCGACCCTTATA
TGCGTGGCCGCATGAGCGATGAACCCTCTTATGCGCCGCCTGTTGAACCTGGCTGCGTTATGGTTGGCGGTACGGTTAGT
CGCGTTGTCGCGTCAAACCATCCTGATTACCGACCAGACGAATGGGTGTTGAGTTACAATGGTTGGCAGGATTATGACAT
TTCAGATGGCGAAGGGTTGGTAAAGCTGGGTGATAATCCGCAACATCCTTCCTGGTCGCTGGGTATTTTAGGAATGCCGG
GGTTTACCGCCTATATGGGGTTACTGGATATCGGCCAGCCGAAAGAGGGCGAAACGCTGGTTGTCGCCGCCGCCACCGGC
CCAGTAGGCGCAACGGTTGGGCAAATTGGCAAGCTGAAGGGCTGCCGGGTCGTGGGTATTGCTGGCGGCGCGGAAAAATG
CCGTCATGCGACAGACGTTTTGGGATTTGATCTGTGCCTCGATCATCACGCTGATAATTTCCCACAACAGCTTGCGCAGG
CCTGCCCGCAGGGTATCGATATCTATTATGAGAATGTCGGTGGTAAAGTCTTTGACGCCGTCTTACCGCTACTGAATACG
TCGGCGCGGATTCCGCTCTGCGGTCTGGTCAGCGGCTACAATGCGACAGCGTTGCCGGACGGTCCAGACAGACTGCCTCT
GCTGATGGCAACATTACTTAAAAAGCGTATTCGCCTGCAAGGTTTTATCATCAACCAGGACTATGGTCACCGGATACATG
AGTTTCAGCAAGAAATGGGGCGTTGGATAAAAGAAGGGAAAATACATTACCGGGAGCAGATTACTGATGGGCTGGAAAAT
GCGCCAGAAGCGTTTATGGGGCTGCTGGCGGGGAAGAACTTTGGCAAAGTCGTGATACGTTTAGCGGACGATGCGTAA

Upstream 100 bases:

>100_bases
CATAAAAGCGCACAGCCTGATATCTGAGAGTGTTTAACTCCCTCAGAAAGCTAATGTTCGACTATTATTGATGGATTATG
CCAGGCATGAGGAGAATAGA

Downstream 100 bases:

>100_bases
AGAAAAAATGGCGGCATTATGTCGCCATAAAAATGTGCAAATTTTAAAATTCCGGCTTTACTTATATTCATCATTCAGAT
CGCGGTGGGGCAGCTTATCT

Product: putative NADP-dependent oxidoreductase yncb

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSDEPSYAPPVEPGCVMVGGTVS
RVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNPQHPSWSLGILGMPGFTAYMGLLDIGQPKEGETLVVAAATG
PVGATVGQIGKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGKVFDAVLPLLNT
SARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHRIHEFQQEMGRWIKEGKIHYREQITDGLEN
APEAFMGLLAGKNFGKVVIRLADDA

Sequences:

>Translated_345_residues
MKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSDEPSYAPPVEPGCVMVGGTVS
RVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNPQHPSWSLGILGMPGFTAYMGLLDIGQPKEGETLVVAAATG
PVGATVGQIGKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGKVFDAVLPLLNT
SARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHRIHEFQQEMGRWIKEGKIHYREQITDGLEN
APEAFMGLLAGKNFGKVVIRLADDA
>Mature_345_residues
MKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSDEPSYAPPVEPGCVMVGGTVS
RVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNPQHPSWSLGILGMPGFTAYMGLLDIGQPKEGETLVVAAATG
PVGATVGQIGKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGKVFDAVLPLLNT
SARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHRIHEFQQEMGRWIKEGKIHYREQITDGLEN
APEAFMGLLAGKNFGKVVIRLADDA

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=351, Percent_Identity=37.8917378917379, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI226246680, Length=351, Percent_Identity=37.8917378917379, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI22748929, Length=351, Percent_Identity=37.8917378917379, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI226059159, Length=338, Percent_Identity=36.6863905325444, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI226059133, Length=338, Percent_Identity=36.6863905325444, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI226056130, Length=310, Percent_Identity=34.5161290322581, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI28557745, Length=341, Percent_Identity=29.0322580645161, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI226510941, Length=344, Percent_Identity=85.7558139534884, Blast_Score=618, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI133901710, Length=358, Percent_Identity=32.9608938547486, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI133901712, Length=358, Percent_Identity=32.9608938547486, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6323504, Length=370, Percent_Identity=27.027027027027, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37763; Mature: 37763

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSD
CCCCCCCCCEEEEEECCCCCCCCCCCEECCCCCCCCCCCCEEEHHHHHHCCHHHHCCCCC
EPSYAPPVEPGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNP
CCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCC
QHPSWSLGILGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGI
CCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEE
AGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGKVFDAVLPLLNT
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCC
SARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHRIHEFQQEMG
CCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHH
RWIKEGKIHYREQITDGLENAPEAFMGLLAGKNFGKVVIRLADDA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSD
CCCCCCCCCEEEEEECCCCCCCCCCCEECCCCCCCCCCCCEEEHHHHHHCCHHHHCCCCC
EPSYAPPVEPGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNP
CCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCC
QHPSWSLGILGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGI
CCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEE
AGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGKVFDAVLPLLNT
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCC
SARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHRIHEFQQEMG
CCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHH
RWIKEGKIHYREQITDGLENAPEAFMGLLAGKNFGKVVIRLADDA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]