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The map label for this gene is fixA [H]

Identifier: 194737337

GI number: 194737337

Start: 88678

End: 89448

Strand: Direct

Name: fixA [H]

Synonym: SeSA_A0085

Alternate gene names: 194737337

Gene position: 88678-89448 (Clockwise)

Preceding gene: 194736996

Following gene: 194738218

Centisome position: 1.88

GC content: 51.88

Gene sequence:

>771_bases
ATGAAGATAATTACTTGCTACAAATGCGTACCTGATGAGCAGGATATTGCGATTAATAATGCTGACGGAACACTCGATTT
CAGCAAAGCGGATAGCAAAATCAGCCAATATGATCTGAATGCAATTGAAGCTGCTTGCCAGTTAAAACAGCAGTTGGGAG
ACGCTCAGGTTGTCGCCATGAGCGTTGGCGGCAAAGCGCTGACTAATGCAAAAGGGCGCAAAGATGTCCTCTCTCGTGGC
CCTGATGAACTGATTGTGGTCATTGACGATCAATTTGAGCAGGCGCTGCCGCAACACACCGCTACCGCGCTGGCCGCTGC
CGCGCAAAAATCAGGTTTCGATCTGCTTATCTGCGGCGACGGTTCTTCCGATCTTTATGCTCAGCAGGTTGGTTTGCTGG
TGGGCGAAGCGTTGAACATTCCGGCGATTAACGGCGTGAGTAAGATCCTCTCTCTTACCGACAGCACATTGACGGTAGAA
CGCGAACTGGAAGATGAAGTTGAAACGCTGAGCATCCCGCTCCCGGCGGTGATCGCGGTTTCCACCGACATTAACACCCC
ACAAATCCCTTCGATGAAAGCCATTCTTGGCGCGGCGAAAAAACCGGTTCAGGTCTGGTCGCCTGCGGATATCGGGCTGA
ACAGCGTACCCGCGTATTCCGCACAACAGGTTACCGTACCGAAGCAGCGCGAGCGTCAGCGTGTGGTGATTGAAGGTGAC
GGTGAAGAACAAATCGCCGCGTTTGTCGAGAATCTGCGCAAAATCATTTAA

Upstream 100 bases:

>100_bases
ATATTGGTGATTAAGGTTTTATTTCCGAATTAAAGAGCGTGATATCTGTATTTAACACCGCCGATATAAATACGTTTCCT
TCATGATTTCTGGAGATGCA

Downstream 100 bases:

>100_bases
TTATCAGGGGATGTTATGAACAAATTTTCCAGTGTCTGGGTATTCAGCGATACCCCTTCTCGTCTGCCCGAACTGATGAG
TGGCGCGCAGGCTGTAGGTG

Product: putative electron transfer flavoprotein FixA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVE
RELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSAQQVTVPKQRERQRVVIEGD
GEEQIAAFVENLRKII

Sequences:

>Translated_256_residues
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVE
RELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSAQQVTVPKQRERQRVVIEGD
GEEQIAAFVENLRKII
>Mature_256_residues
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVE
RELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSAQQVTVPKQRERQRVVIEGD
GEEQIAAFVENLRKII

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI62420877, Length=192, Percent_Identity=30.2083333333333, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87081682, Length=256, Percent_Identity=87.109375, Blast_Score=436, Evalue=1e-124,
Organism=Escherichia coli, GI2367123, Length=255, Percent_Identity=56.078431372549, Blast_Score=266, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI25141345, Length=200, Percent_Identity=25, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 27280; Mature: 27280

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS01065 ETF_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAM
CCEEEEEECCCCCCCEEEECCCCCEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
SVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGD
ECCCCHHCCCCCHHHHHHCCCCEEEEEEECHHHHHCHHHHHHHHHHHHHCCCCEEEEECC
GSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVERELEDEVETLSIPLPAVIAV
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCEEEEE
STDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSAQQVTVPKQRERQRVVIEGD
ECCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECC
GEEQIAAFVENLRKII
CHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEAACQLKQQLGDAQVVAM
CCEEEEEECCCCCCCEEEECCCCCEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
SVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQHTATALAAAAQKSGFDLLICGD
ECCCCHHCCCCCHHHHHHCCCCEEEEEEECHHHHHCHHHHHHHHHHHHHCCCCEEEEECC
GSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVERELEDEVETLSIPLPAVIAV
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCEEEEE
STDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPAYSAQQVTVPKQRERQRVVIEGD
ECCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECC
GEEQIAAFVENLRKII
CHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA