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The map label for this gene is treC [H]

Identifier: 194737289

GI number: 194737289

Start: 4571114

End: 4572766

Strand: Reverse

Name: treC [H]

Synonym: SeSA_A4705

Alternate gene names: 194737289

Gene position: 4572766-4571114 (Counterclockwise)

Preceding gene: 194737770

Following gene: 194736623

Centisome position: 97.11

GC content: 55.47

Gene sequence:

>1653_bases
ATGACTATTCCCCTCTGGTGGCAAAACGGCGTTATTTATCAGATCTACCCAAAAAGTTTTCAGGACACGACCGGCAGCGG
CACCGGCGATTTACGCGGCGTCACGCAGCACCTTGACTATCTACAGCGACTCGGCGTGGATGCCATCTGGCTCACGCCGT
TTTATATCTCGCCGCAGGTGGATAACGGTTATGACGTCGCAAATTATACGGCCATCGACCCGACCTACGGCACGCTGGAT
GATTTTGACGAGCTGGTCGCGCAGGCGAAAGCACGCGGTATTCGCATCATCCTGGATATGGTGTTTAACCATACTTCTAC
CCAGCACGCCTGGTTTCGCGAAGCGCTGAACAAAGAGAGTCCATACCGTCAGTTTTATATCTGGCGCGATGGCACGCCGG
ATGTCTGCCCGAATAACTGGCAATCCAAATTTGGCGGCAGCGCCTGGCGCTGGCATAGCCAGAGCGAACAATATTATTTA
CACCTTTTCGCGCCTGAACAGGCCGACCTGAACTGGGAAAACCCCGCCGTGCGCGCCGAGCTGAAAAAGGTCTGCGAATT
CTGGGCCGATCGCGGCGTGGATGGCCTGCGTCTGGACGTGGTGAACCTGATCGCCAAAGATCAGGATTTTCCTGACGATC
CGACGGGCGACGGACGCCGCTTTTATACCGACGGACCGCGCGCGCATACGTTTTTACGCGAAATGAACCGTGACGTTTTT
ACGCCGCGTAATCTGATGACGGTAGGCGAAATGTCCTCTACCACGCTGGAAAACTGCCAGCAATATGCCGCGCTTAGCGG
CGACGAACTCTCGATGACCTTCAATTTTCATCATCTGAAGGTGGATTACCCCAATGGCGAAAAGTGGACGCTGGCAAAAC
CTGATTATGTGGCGCTGAAAGCGTTGTTCCGCCACTGGCAACAGGGGATGCATAACGTCGCCTGGAACGCGTTATTCTGG
TGTAATCACGATCAGCCGCGCATCGTTTCCCGCTTTGGCGACGAGGGTGAATACCGGGTTCCAGCCGCGAAAATGTTGGC
GATGGCGCTGCACGGTATGCAAGGGACGCCTTATATCTATCAGGGCGAAGAAATCGGCATGACCAACCCACACTTTACCC
GCATCACCGATTATCGCGACGTGGAAAGCCATAACATGTTTGCCGCGCTACGCGCCGCCGGACGCGACCCCGACGAACTA
CTGGCTATCCTGGCCAGTAAATCCCGCGACAACAGCCGCACGCCGATGCAGTGGAACCACGGTAAAAACGCCGGTTTCAC
CCAGGGCGAGCCGTGGATAAGCCTGTGCGATAACTATACGGAGGTTAATGTCGCGGCGGCATTACGCGATGAAAACTCGG
TGTTTTACACCTATCAAAAGCTGATTGCGCTACGTAAAACCCAGCCTGTACTGATCTGGGGCGATTATCAGGATCTCCTC
CCGGATAGCCCATCAGTATGGTGTTATCGTCGCCAGTGGCAGGGGCAAACCCTGCTGGTTGTCGCCAATCTGAGCGACCA
GTGTCAGGAGTGGCATCCACCGCATATCAAAGGACAGTGGCAGGCGCTACTGCACAATTATGGCGAGGTCGCCAGCCAGC
CAGCCGCGATGACGCTCCGCCCATTTGAAGCCATCTGGTGGTTACAACGCTAA

Upstream 100 bases:

>100_bases
ACCTTTATCTATCAGCGTAAGCATCGTCAGGGCACATTACAAATTGTCTAATACTTCTTCGGGGCGCAGTTGCGTCCCAA
CGCACTTGCAGGAAACAACA

Downstream 100 bases:

>100_bases
CGCGACGTCCTTATACGGATAAACGCCACAGGCCTATTGACACGGGCTGTGGCGTTGCTCCTGGTTACTGTCTGTTTTTG
TTGAATAATTAATCAGATTT

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTIPLWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTQHLDYLQRLGVDAIWLTPFYISPQVDNGYDVANYTAIDPTYGTLD
DFDELVAQAKARGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGTPDVCPNNWQSKFGGSAWRWHSQSEQYYL
HLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLIAKDQDFPDDPTGDGRRFYTDGPRAHTFLREMNRDVF
TPRNLMTVGEMSSTTLENCQQYAALSGDELSMTFNFHHLKVDYPNGEKWTLAKPDYVALKALFRHWQQGMHNVAWNALFW
CNHDQPRIVSRFGDEGEYRVPAAKMLAMALHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESHNMFAALRAAGRDPDEL
LAILASKSRDNSRTPMQWNHGKNAGFTQGEPWISLCDNYTEVNVAAALRDENSVFYTYQKLIALRKTQPVLIWGDYQDLL
PDSPSVWCYRRQWQGQTLLVVANLSDQCQEWHPPHIKGQWQALLHNYGEVASQPAAMTLRPFEAIWWLQR

Sequences:

>Translated_550_residues
MTIPLWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTQHLDYLQRLGVDAIWLTPFYISPQVDNGYDVANYTAIDPTYGTLD
DFDELVAQAKARGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGTPDVCPNNWQSKFGGSAWRWHSQSEQYYL
HLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLIAKDQDFPDDPTGDGRRFYTDGPRAHTFLREMNRDVF
TPRNLMTVGEMSSTTLENCQQYAALSGDELSMTFNFHHLKVDYPNGEKWTLAKPDYVALKALFRHWQQGMHNVAWNALFW
CNHDQPRIVSRFGDEGEYRVPAAKMLAMALHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESHNMFAALRAAGRDPDEL
LAILASKSRDNSRTPMQWNHGKNAGFTQGEPWISLCDNYTEVNVAAALRDENSVFYTYQKLIALRKTQPVLIWGDYQDLL
PDSPSVWCYRRQWQGQTLLVVANLSDQCQEWHPPHIKGQWQALLHNYGEVASQPAAMTLRPFEAIWWLQR
>Mature_549_residues
TIPLWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTQHLDYLQRLGVDAIWLTPFYISPQVDNGYDVANYTAIDPTYGTLDD
FDELVAQAKARGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGTPDVCPNNWQSKFGGSAWRWHSQSEQYYLH
LFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLIAKDQDFPDDPTGDGRRFYTDGPRAHTFLREMNRDVFT
PRNLMTVGEMSSTTLENCQQYAALSGDELSMTFNFHHLKVDYPNGEKWTLAKPDYVALKALFRHWQQGMHNVAWNALFWC
NHDQPRIVSRFGDEGEYRVPAAKMLAMALHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESHNMFAALRAAGRDPDELL
AILASKSRDNSRTPMQWNHGKNAGFTQGEPWISLCDNYTEVNVAAALRDENSVFYTYQKLIALRKTQPVLIWGDYQDLLP
DSPSVWCYRRQWQGQTLLVVANLSDQCQEWHPPHIKGQWQALLHNYGEVASQPAAMTLRPFEAIWWLQR

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=560, Percent_Identity=29.1071428571429, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI65506891, Length=107, Percent_Identity=35.5140186915888, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI61744483, Length=107, Percent_Identity=35.5140186915888, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI61744479, Length=107, Percent_Identity=35.5140186915888, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI61744475, Length=107, Percent_Identity=35.5140186915888, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI61744481, Length=107, Percent_Identity=35.5140186915888, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI61744477, Length=107, Percent_Identity=35.5140186915888, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1790687, Length=548, Percent_Identity=84.4890510948905, Blast_Score=989, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=186, Percent_Identity=32.258064516129, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789995, Length=184, Percent_Identity=28.804347826087, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=490, Percent_Identity=25.5102040816327, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32565753, Length=522, Percent_Identity=23.1800766283525, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321726, Length=578, Percent_Identity=36.159169550173, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6322245, Length=584, Percent_Identity=35.7876712328767, Blast_Score=358, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6322241, Length=578, Percent_Identity=36.5051903114187, Blast_Score=353, Evalue=5e-98,
Organism=Saccharomyces cerevisiae, GI6322021, Length=578, Percent_Identity=36.5051903114187, Blast_Score=353, Evalue=5e-98,
Organism=Saccharomyces cerevisiae, GI6324416, Length=578, Percent_Identity=36.5051903114187, Blast_Score=352, Evalue=6e-98,
Organism=Saccharomyces cerevisiae, GI6321731, Length=588, Percent_Identity=35.2040816326531, Blast_Score=337, Evalue=4e-93,
Organism=Saccharomyces cerevisiae, GI6319776, Length=588, Percent_Identity=35.0340136054422, Blast_Score=335, Evalue=1e-92,
Organism=Drosophila melanogaster, GI24583745, Length=538, Percent_Identity=36.0594795539033, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI24583747, Length=542, Percent_Identity=35.0553505535055, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI24583749, Length=542, Percent_Identity=35.0553505535055, Blast_Score=291, Evalue=8e-79,
Organism=Drosophila melanogaster, GI221330053, Length=535, Percent_Identity=35.5140186915888, Blast_Score=288, Evalue=7e-78,
Organism=Drosophila melanogaster, GI45549022, Length=534, Percent_Identity=35.0187265917603, Blast_Score=274, Evalue=9e-74,
Organism=Drosophila melanogaster, GI24586599, Length=582, Percent_Identity=32.3024054982818, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24586597, Length=537, Percent_Identity=33.5195530726257, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24586587, Length=500, Percent_Identity=33.8, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24586589, Length=530, Percent_Identity=34.5283018867924, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24586593, Length=535, Percent_Identity=32.5233644859813, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI24586591, Length=579, Percent_Identity=31.0880829015544, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI281360393, Length=480, Percent_Identity=30.4166666666667, Blast_Score=186, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63570; Mature: 63439

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPLWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTQHLDYLQRLGVDAIWLTPFYISPQV
CEEEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCC
DNGYDVANYTAIDPTYGTLDDFDELVAQAKARGIRIILDMVFNHTSTQHAWFREALNKES
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHHCCCC
PYRQFYIWRDGTPDVCPNNWQSKFGGSAWRWHSQSEQYYLHLFAPEQADLNWENPAVRAE
CCEEEEEEECCCCCCCCCCCHHHCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHH
LKKVCEFWADRGVDGLRLDVVNLIAKDQDFPDDPTGDGRRFYTDGPRAHTFLREMNRDVF
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCC
TPRNLMTVGEMSSTTLENCQQYAALSGDELSMTFNFHHLKVDYPNGEKWTLAKPDYVALK
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCEEEECCCCHHHHH
ALFRHWQQGMHNVAWNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMALHGMQGTPYIY
HHHHHHHHHHHHHHCEEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEEE
QGEEIGMTNPHFTRITDYRDVESHNMFAALRAAGRDPDELLAILASKSRDNSRTPMQWNH
ECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCC
GKNAGFTQGEPWISLCDNYTEVNVAAALRDENSVFYTYQKLIALRKTQPVLIWGDYQDLL
CCCCCCCCCCCHHHHCCCCCEEEEEEEEECCCCEEHHHHHHHHHHCCCCEEEECCHHHHC
PDSPSVWCYRRQWQGQTLLVVANLSDQCQEWHPPHIKGQWQALLHNYGEVASQPAAMTLR
CCCCCEEEEEEECCCCEEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEC
PFEAIWWLQR
HHHHHHEECC
>Mature Secondary Structure 
TIPLWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTQHLDYLQRLGVDAIWLTPFYISPQV
EEEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCC
DNGYDVANYTAIDPTYGTLDDFDELVAQAKARGIRIILDMVFNHTSTQHAWFREALNKES
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHHCCCC
PYRQFYIWRDGTPDVCPNNWQSKFGGSAWRWHSQSEQYYLHLFAPEQADLNWENPAVRAE
CCEEEEEEECCCCCCCCCCCHHHCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHH
LKKVCEFWADRGVDGLRLDVVNLIAKDQDFPDDPTGDGRRFYTDGPRAHTFLREMNRDVF
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCC
TPRNLMTVGEMSSTTLENCQQYAALSGDELSMTFNFHHLKVDYPNGEKWTLAKPDYVALK
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCEEEECCCCHHHHH
ALFRHWQQGMHNVAWNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMALHGMQGTPYIY
HHHHHHHHHHHHHHCEEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEEE
QGEEIGMTNPHFTRITDYRDVESHNMFAALRAAGRDPDELLAILASKSRDNSRTPMQWNH
ECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCC
GKNAGFTQGEPWISLCDNYTEVNVAAALRDENSVFYTYQKLIALRKTQPVLIWGDYQDLL
CCCCCCCCCCCHHHHCCCCCEEEEEEEEECCCCEEHHHHHHHHHHCCCCEEEECCHHHHC
PDSPSVWCYRRQWQGQTLLVVANLSDQCQEWHPPHIKGQWQALLHNYGEVASQPAAMTLR
CCCCCEEEEEEECCCCEEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEC
PFEAIWWLQR
HHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]