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The map label for this gene is etfA [H]

Identifier: 194737170

GI number: 194737170

Start: 980604

End: 981557

Strand: Direct

Name: etfA [H]

Synonym: SeSA_A1007

Alternate gene names: 194737170

Gene position: 980604-981557 (Clockwise)

Preceding gene: 194736689

Following gene: 194735942

Centisome position: 20.82

GC content: 41.72

Gene sequence:

>954_bases
ATGGCTTCTTTAGTTATTGCTGAACATAACGGCAATACTCTTTTACCTTCAACACTCAGTACTATCACTGCGGCAAAAGC
CATTAATAGTGATATAGATATACTTATGTTAGGATATGGTATAGAAAGTATTGCAGTTAAAGCCAGTCATATTCAGGGGA
TATCCACTGTATTTGTTGCTGACAGCCCACTATTCGAACACCTTCTGGCAGAGAATGTGGAAAAACAGATCAGCTATTTT
TTGAATAGTGGGAAAAATCATTATCAGTCCATTCTTTTTCCTGCAAGCTCTTTTGGAAAAAACTGTGCGCCACGCTTAGC
AGCAAAACTTGATGTATCTCAGATTAGTGATATTACGCGTGTCATTGATCAACATACCTTTGAACGTCCAATCTATGCGG
GTAACGCTATTGCCACAGTACACAGTGATGATGAATATAAAGTGATAACTGTTCGTCCTACCTCATTTGCGGCTGCGGCT
GCGGTTGCGGAAGATGAGGGAAAAGCCCCCATTGAATTTACAGAGGTTGTTCTTGGTTCAGATCAGGTAAAATTTATTAG
CCAACATGTTAATAAAAGTAACCGTCCAGACTTACAATCCGCCAGAGTTGTAGTATCAGGTGGACGAGGAGTAGGAAGTG
CACAGGCATTCAAAGAACTTGTTGATAACCTGGCAGATAAATTAGGCGCTGCCGTGGGGGCAAGCCGGGCTGCTGTAGAT
GCTGGTTATGCACCAAATGATTATCAGATTGGCCAGACCGGAAAAATCGTTGCGCCTCAACTTTATATTGCTCTGGGAAT
TTCTGGCGCCATACAACATCTTGCCGGGATGAAAGAGTCAGGCGTCATTGTCGCTATTAATAAGGATCCTGACGCTCCTA
TCTTTTCTATTGCGGATTATGGTTTGGTAGCTGATATTTTCAAAGCTGTACCTGAACTTATCGATAAATTATAA

Upstream 100 bases:

>100_bases
GATGAGCCAGCAAGAAGGAAAGCAGGCATAATCGTTCCAGATATTAACACGCTGCTAGATAAATTAAAAAACGAAGAAAA
AGTAATTTAAGGAGAAAAAT

Downstream 100 bases:

>100_bases
ATCATATTTTTTCCTCCTTAAAGGTAACTTTTATGCAATATACTGATATTCAAATTTGGCAGCTTGGCATTCTGCGCAAC
ACCGATTATCTTAACCCCGG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MASLVIAEHNGNTLLPSTLSTITAAKAINSDIDILMLGYGIESIAVKASHIQGISTVFVADSPLFEHLLAENVEKQISYF
LNSGKNHYQSILFPASSFGKNCAPRLAAKLDVSQISDITRVIDQHTFERPIYAGNAIATVHSDDEYKVITVRPTSFAAAA
AVAEDEGKAPIEFTEVVLGSDQVKFISQHVNKSNRPDLQSARVVVSGGRGVGSAQAFKELVDNLADKLGAAVGASRAAVD
AGYAPNDYQIGQTGKIVAPQLYIALGISGAIQHLAGMKESGVIVAINKDPDAPIFSIADYGLVADIFKAVPELIDKL

Sequences:

>Translated_317_residues
MASLVIAEHNGNTLLPSTLSTITAAKAINSDIDILMLGYGIESIAVKASHIQGISTVFVADSPLFEHLLAENVEKQISYF
LNSGKNHYQSILFPASSFGKNCAPRLAAKLDVSQISDITRVIDQHTFERPIYAGNAIATVHSDDEYKVITVRPTSFAAAA
AVAEDEGKAPIEFTEVVLGSDQVKFISQHVNKSNRPDLQSARVVVSGGRGVGSAQAFKELVDNLADKLGAAVGASRAAVD
AGYAPNDYQIGQTGKIVAPQLYIALGISGAIQHLAGMKESGVIVAINKDPDAPIFSIADYGLVADIFKAVPELIDKL
>Mature_316_residues
ASLVIAEHNGNTLLPSTLSTITAAKAINSDIDILMLGYGIESIAVKASHIQGISTVFVADSPLFEHLLAENVEKQISYFL
NSGKNHYQSILFPASSFGKNCAPRLAAKLDVSQISDITRVIDQHTFERPIYAGNAIATVHSDDEYKVITVRPTSFAAAAA
VAEDEGKAPIEFTEVVLGSDQVKFISQHVNKSNRPDLQSARVVVSGGRGVGSAQAFKELVDNLADKLGAAVGASRAAVDA
GYAPNDYQIGQTGKIVAPQLYIALGISGAIQHLAGMKESGVIVAINKDPDAPIFSIADYGLVADIFKAVPELIDKL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=322, Percent_Identity=51.5527950310559, Blast_Score=299, Evalue=2e-81,
Organism=Homo sapiens, GI189181759, Length=282, Percent_Identity=52.8368794326241, Blast_Score=267, Evalue=9e-72,
Organism=Escherichia coli, GI1787990, Length=251, Percent_Identity=35.0597609561753, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786226, Length=232, Percent_Identity=34.051724137931, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082157, Length=227, Percent_Identity=31.7180616740088, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17506929, Length=318, Percent_Identity=51.2578616352201, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6325261, Length=275, Percent_Identity=44, Blast_Score=222, Evalue=7e-59,
Organism=Drosophila melanogaster, GI17136898, Length=317, Percent_Identity=54.2586750788643, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24652801, Length=317, Percent_Identity=54.2586750788643, Blast_Score=305, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33516; Mature: 33385

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLVIAEHNGNTLLPSTLSTITAAKAINSDIDILMLGYGIESIAVKASHIQGISTVFVA
CCEEEEEECCCCEECCHHHHHHHHHHHHCCCCCEEEEECCHHHHEEEHHHHCCCEEEEEE
DSPLFEHLLAENVEKQISYFLNSGKNHYQSILFPASSFGKNCAPRLAAKLDVSQISDITR
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCHHHCCCCHHHHHHHCCHHHHHHHHH
VIDQHTFERPIYAGNAIATVHSDDEYKVITVRPTSFAAAAAVAEDEGKAPIEFTEVVLGS
HHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHEECCC
DQVKFISQHVNKSNRPDLQSARVVVSGGRGVGSAQAFKELVDNLADKLGAAVGASRAAVD
HHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHC
AGYAPNDYQIGQTGKIVAPQLYIALGISGAIQHLAGMKESGVIVAINKDPDAPIFSIADY
CCCCCCCCEECCCCCEECCEEEEEECHHHHHHHHHCCCCCCEEEEECCCCCCCEEEHHHH
GLVADIFKAVPELIDKL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASLVIAEHNGNTLLPSTLSTITAAKAINSDIDILMLGYGIESIAVKASHIQGISTVFVA
CEEEEEECCCCEECCHHHHHHHHHHHHCCCCCEEEEECCHHHHEEEHHHHCCCEEEEEE
DSPLFEHLLAENVEKQISYFLNSGKNHYQSILFPASSFGKNCAPRLAAKLDVSQISDITR
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCHHHCCCCHHHHHHHCCHHHHHHHHH
VIDQHTFERPIYAGNAIATVHSDDEYKVITVRPTSFAAAAAVAEDEGKAPIEFTEVVLGS
HHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHEECCC
DQVKFISQHVNKSNRPDLQSARVVVSGGRGVGSAQAFKELVDNLADKLGAAVGASRAAVD
HHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHC
AGYAPNDYQIGQTGKIVAPQLYIALGISGAIQHLAGMKESGVIVAINKDPDAPIFSIADY
CCCCCCCCEECCCCCEECCEEEEEECHHHHHHHHHCCCCCCEEEEECCCCCCCEEEHHHH
GLVADIFKAVPELIDKL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]