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The map label for this gene is creB [H]

Identifier: 194737123

GI number: 194737123

Start: 4695875

End: 4696564

Strand: Direct

Name: creB [H]

Synonym: SeSA_A4839

Alternate gene names: 194737123

Gene position: 4695875-4696564 (Clockwise)

Preceding gene: 194736465

Following gene: 194735190

Centisome position: 99.72

GC content: 58.12

Gene sequence:

>690_bases
ATGCAGCAACCGCAGGTCTGGTTAGTCGAGGATGAACAGGGAATCGCCGATACGCTCATCTACACCCTGCAACTGGAAGG
GTTTACCGTTGAGCTATTCGCTCGCGGGCTGCCCGCGCTGGAAAAAGCGCGTCAGCAACGGCCGGATGCGGTGATTCTCG
ATGTGGGACTGCCGGATATCAGCGGCTTTGAGCTGTGTCGGCAGTTGCTGGAACGCCATCCTGCGCTGCCGATTCTTTTC
CTGACTGCCCGTAGCGATGAAGTGGATCGATTGCTTGGTCTGGAGATCGGCGCAGATGATTATGTCGCCAAGCCGTTCTC
GCCGCGCGAAGTGAGCGCCCGCGTGCGCACGCTGCTGCGCCGGGTGAAAAAGTTTGCTGCGCCGTCGCCGGTGGTGCGTA
CCGGACATTTTGAACTCAATGAACCGGCGGCGCAGATCGCCTGGTTTGGTACGCCGCTCTCGCTGACGCGTTATGAGTTT
CTGCTTCTTAAAACCCTGCTGCTGTCGCCGGAGCGCGTGTACTCGCGTCAGCAATTGATGGATATTGTCTGGTCTGATGC
CCAGGAGACCTACGATCGGACGGTCGATACACACATCAAAACCCTGCGCGCTAAACTACGCGCGATCAACCCGGATCTCT
CGCCAATTAACACGCATCGTGGAATGGGATACAGCCTGAGGAGCGTCTGA

Upstream 100 bases:

>100_bases
GGCGTATCTGGCCTACTCCGACAAAGTAGTCGACGGGTCGCCGAAGAACGCCATCAGCGCGGTGCCGGTCATGCCGTGGC
GACAATAACAGGGAAAGAGT

Downstream 100 bases:

>100_bases
TGCGCATCGGAATGCGTTTGCTACTGGGCTACTTTCTTATTGTCGCCGTCGCCGCCGTGTTTGTGCTGTCTATCTTCGTT
CAGGAGATAAAGCCGGGCGT

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDISGFELCRQLLERHPALPILF
LTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLRRVKKFAAPSPVVRTGHFELNEPAAQIAWFGTPLSLTRYEF
LLLKTLLLSPERVYSRQQLMDIVWSDAQETYDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSV

Sequences:

>Translated_229_residues
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDISGFELCRQLLERHPALPILF
LTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLRRVKKFAAPSPVVRTGHFELNEPAAQIAWFGTPLSLTRYEF
LLLKTLLLSPERVYSRQQLMDIVWSDAQETYDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSV
>Mature_229_residues
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDISGFELCRQLLERHPALPILF
LTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLRRVKKFAAPSPVVRTGHFELNEPAAQIAWFGTPLSLTRYEF
LLLKTLLLSPERVYSRQQLMDIVWSDAQETYDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSV

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=84.7161572052402, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=42.7312775330396, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=35.3982300884956, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.7142857142857, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=36.322869955157, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=36.8421052631579, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=33.7777777777778, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=36.7713004484305, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=32.8828828828829, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=33.7662337662338, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=33.6363636363636, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=31.1111111111111, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790299, Length=146, Percent_Identity=32.1917808219178, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=26.2008733624454, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790437, Length=142, Percent_Identity=28.8732394366197, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26033; Mature: 26033

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDI
CCCCCEEEEECCCCHHHHEEEEEEECCEEEEHHHCCCHHHHHHHHCCCCEEEEECCCCCC
SGFELCRQLLERHPALPILFLTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLR
CHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHH
RVKKFAAPSPVVRTGHFELNEPAAQIAWFGTPLSLTRYEFLLLKTLLLSPERVYSRQQLM
HHHHHCCCCCCEECCCEECCCCHHHEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
DIVWSDAQETYDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDI
CCCCCEEEEECCCCHHHHEEEEEEECCEEEEHHHCCCHHHHHHHHCCCCEEEEECCCCCC
SGFELCRQLLERHPALPILFLTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLR
CHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHH
RVKKFAAPSPVVRTGHFELNEPAAQIAWFGTPLSLTRYEFLLLKTLLLSPERVYSRQQLM
HHHHHCCCCCCEECCCEECCCCHHHEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
DIVWSDAQETYDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]