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The map label for this gene is eco [H]

Identifier: 194736714

GI number: 194736714

Start: 2365825

End: 2366331

Strand: Direct

Name: eco [H]

Synonym: SeSA_A2488

Alternate gene names: 194736714

Gene position: 2365825-2366331 (Clockwise)

Preceding gene: 194736026

Following gene: 194735763

Centisome position: 50.24

GC content: 54.04

Gene sequence:

>507_bases
GTGAACAATCAAATGAAGATGTTTGTCCCTGCCGTCGTCTTCGCCGCCCTCGCCAGCGCCTCTGCCTGGGCTAACAATAG
CGATACCGCCCAGCCGCTGGAGAAAATCGCCCCCTATCCGCAGGCGGAAAAAGGAATGAAGCGGCAAGTGATAACCCTTA
CCCCTCAGCAGGATGAATCTACCCTCAAAGTGGAACTGTTGATTGGCCAAACGCTGAATGTGGATTGTAACCAGCATCGC
CTCGGCGGCACGCTGGAAACAAAAACGCTGGAAGGCTGGGGCTATGACTATTATGTCTTTGATAACGTCACCTCTCCGGT
ATCAACCATGATGGCCTGCCCTGAAGGTAAGAAAGAGCAAAAATTCGTCACCGCCTGGCTGGGTGAAGACGGGATGCTGC
GCTACAACAGCAAGCTGCCGATCGTGGTGTATACCCCGGCGAATGTAGACGTGAAATACCGCATCTGGAAAGCGGACGCT
AACGTACAGAACGCCGTCGCGCGATAA

Upstream 100 bases:

>100_bases
ATTAATAATCTTGAAAATATGAGTAAATACAGATTAATAGATAATATGAATGTGTTAATCTGTTGTCCGTGCATACCGAA
AACAGCAGAAAGGAAATACT

Downstream 100 bases:

>100_bases
TGTTACGCTGCCCGGTCACACTTACCGGGCATCTGAACACGCCGGCTCACGCAGCGCTCCGGGGTTCTTTTTAAAACACG
TCTGGAAATCCGCTCGCCCG

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MNNQMKMFVPAVVFAALASASAWANNSDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKVELLIGQTLNVDCNQHR
LGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADA
NVQNAVAR

Sequences:

>Translated_168_residues
MNNQMKMFVPAVVFAALASASAWANNSDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKVELLIGQTLNVDCNQHR
LGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADA
NVQNAVAR
>Mature_168_residues
MNNQMKMFVPAVVFAALASASAWANNSDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKVELLIGQTLNVDCNQHR
LGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADA
NVQNAVAR

Specific function: General inhibitor of pancreatic serine proteases:inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=164, Percent_Identity=79.2682926829268, Blast_Score=277, Evalue=2e-76,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 18736; Mature: 18736

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQMKMFVPAVVFAALASASAWANNSDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDES
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
TLKVELLIGQTLNVDCNQHRLGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQ
EEEEEEEECCEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHCCCCCCCCC
KFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQNAVAR
EEEEEEECCCCEEEECCCCCEEEECCCCCEEEEEEEECCCCHHHHHCC
>Mature Secondary Structure
MNNQMKMFVPAVVFAALASASAWANNSDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDES
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
TLKVELLIGQTLNVDCNQHRLGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQ
EEEEEEEECCEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHCCCCCCCCC
KFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQNAVAR
EEEEEEECCCCEEEECCCCCEEEECCCCCEEEEEEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA