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The map label for this gene is csiR [H]

Identifier: 194736700

GI number: 194736700

Start: 2851578

End: 2852255

Strand: Direct

Name: csiR [H]

Synonym: SeSA_A2939

Alternate gene names: 194736700

Gene position: 2851578-2852255 (Clockwise)

Preceding gene: 194736084

Following gene: 194735773

Centisome position: 60.55

GC content: 56.49

Gene sequence:

>678_bases
ATGACCGCCCTTTCCCAACCGACGGCCATAGATGGCTATCGCTGGCTTAAAAATGACATTATTCGCGGCACTTATCAGCC
GGATGAGAAACTGCGGATGAGTTTATTAACCGCCCGCTATGCGCTCGGCGTAGGGCCGCTGCGCGAGGCGCTGTCGCAAC
TGGTGGCGGAACGGCTGGTCACCGTGGTGAATCAAAAAGGCTATCGCGTGGCATCCATGTCAGAGGCGGAACTCCTCGAT
ATTTTTGACGCGCGCGCCAATATGGAAGCGATGCTGGTACGCCTGGCGATTGAACGCGGCGATGATGCGTGGGAGGCGGA
GATCCTGGCGCGAGCGCATATGCTCAGTAAACTGGAAGCCAGCGATGCCAGTGAACATATGCTCGATGAATGGGACCAGC
GCCACCAGGCGTTCCATTCCGCCATTGTCGCCGGGTGCGGCTCCCACTATCTGCTACAGATGCGTGAACGCTTATTTGAC
CTGGCGGCCCGCTACCGCTTTATTTGGTTACGTGAAACCGTTCTGTCCGTCGAGATGCTGGAAGATAAACATATTCAGCA
TCACACGCTAACCGAAGCGATACTGGCGCGCGAGGCGGCACGCGCCAGCGAATTAATGCGTCAGCATTTGCTGACGCCGA
TTCCCATTATTCGCCAGGCGATGGCAGGAAAAATGTAG

Upstream 100 bases:

>100_bases
TGTCTCGCTGGAAAAAACTGATAAGGTGGCAAAAAGCCCCCCTGCAAAACCTACGTTAGTTATTCCCGGCGTCAGCCGGG
AAGCTTCTCAGGAGTAAAAG

Downstream 100 bases:

>100_bases
CCTGGCGCGGCCTGATAGCCATTATTCTTCAGGAATACGCAACACTTGTCCCGGATATATTTTTTCCGGGCTTTTCAGCA
TCGGTTTATTTGCCTCGAAG

Product: DNA-binding transcriptional regulator CsiR

Products: NA

Alternate protein names: Carbon starvation induced regulator [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTALSQPTAIDGYRWLKNDIIRGTYQPDEKLRMSLLTARYALGVGPLREALSQLVAERLVTVVNQKGYRVASMSEAELLD
IFDARANMEAMLVRLAIERGDDAWEAEILARAHMLSKLEASDASEHMLDEWDQRHQAFHSAIVAGCGSHYLLQMRERLFD
LAARYRFIWLRETVLSVEMLEDKHIQHHTLTEAILAREAARASELMRQHLLTPIPIIRQAMAGKM

Sequences:

>Translated_225_residues
MTALSQPTAIDGYRWLKNDIIRGTYQPDEKLRMSLLTARYALGVGPLREALSQLVAERLVTVVNQKGYRVASMSEAELLD
IFDARANMEAMLVRLAIERGDDAWEAEILARAHMLSKLEASDASEHMLDEWDQRHQAFHSAIVAGCGSHYLLQMRERLFD
LAARYRFIWLRETVLSVEMLEDKHIQHHTLTEAILAREAARASELMRQHLLTPIPIIRQAMAGKM
>Mature_224_residues
TALSQPTAIDGYRWLKNDIIRGTYQPDEKLRMSLLTARYALGVGPLREALSQLVAERLVTVVNQKGYRVASMSEAELLDI
FDARANMEAMLVRLAIERGDDAWEAEILARAHMLSKLEASDASEHMLDEWDQRHQAFHSAIVAGCGSHYLLQMRERLFDL
AARYRFIWLRETVLSVEMLEDKHIQHHTLTEAILAREAARASELMRQHLLTPIPIIRQAMAGKM

Specific function: Modulates expression of csiD and lhgO in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082149, Length=217, Percent_Identity=87.5576036866359, Blast_Score=393, Evalue=1e-111,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25693; Mature: 25562

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALSQPTAIDGYRWLKNDIIRGTYQPDEKLRMSLLTARYALGVGPLREALSQLVAERLV
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TVVNQKGYRVASMSEAELLDIFDARANMEAMLVRLAIERGDDAWEAEILARAHMLSKLEA
HHHHCCCCEEECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SDASEHMLDEWDQRHQAFHSAIVAGCGSHYLLQMRERLFDLAARYRFIWLRETVLSVEML
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDKHIQHHTLTEAILAREAARASELMRQHLLTPIPIIRQAMAGKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TALSQPTAIDGYRWLKNDIIRGTYQPDEKLRMSLLTARYALGVGPLREALSQLVAERLV
CCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TVVNQKGYRVASMSEAELLDIFDARANMEAMLVRLAIERGDDAWEAEILARAHMLSKLEA
HHHHCCCCEEECCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SDASEHMLDEWDQRHQAFHSAIVAGCGSHYLLQMRERLFDLAARYRFIWLRETVLSVEML
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDKHIQHHTLTEAILAREAARASELMRQHLLTPIPIIRQAMAGKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8297211; 7984428 [H]